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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 23671 |
Name | TMEFF2 |
Synonym | CT120.2|HPP1|TENB2|TPEF|TR;transmembrane protein with EGF-like and two follistatin-like domains 2;TMEFF2;transmembrane protein with EGF-like and two follistatin-like domains 2 |
Definition | TR-2|cancer/testis antigen family 120, member 2|hyperplastic polyposis protein 1|tomoregulin|tomoregulin-2|transmembrane protein TENB2 |
Position | 2q32.3 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
potential | the tumor suppressor activity of TMEFF2 requires the cytoplasmic/transmembrane portion of the protein and correlates with its ability to bind to SARDH and to modulate the level of sarcosine. |
potential | data provides evidence to support the role of HPP1 as a tumor suppressor gene; activation of the STAT1 pathway likely represents the principal mediator of HPP1's tumor suppressive properties. |
| More detail of all 2 literatures about TMEFF2 | |
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Pathways and Diseases |
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Pathway | Validated targets of C-MYC transcriptional repression;PID Curated;200171 |
Disease | Diabetes (incident);NHGRI |
Disease | METABOLIC;GAD |
Disease | diabetes (incident);GAD |
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External Links |
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Links to Entrez Gene | 23671 |
Links to all GeneRIF Items | 23671 |
Links to iHOP | 23671 |
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Sequence Information |
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Nucleotide Sequence |
>23671 : length: 1125 atggtgctgtgggagtccccgcggcagtgcagcagctggacactttgcgagggcttttgc tggctgctgctgctgcccgtcatgctactcatcgtagcccgcccggtgaagctcgctgct ttccctacctccttaagtgactgccaaacgcccaccggctggaattgctctggttatgat gacagagaaaatgatctcttcctctgtgacaccaacacctgtaaatttgatggggaatgt ttaagaattggagacactgtgacttgcgtctgtcagttcaagtgcaacaatgactatgtg cctgtgtgtggctccaatggggagagctaccagaatgagtgttacctgcgacaggctgca tgcaaacagcagagtgagatacttgtggtgtcagaaggatcatgtgccacagatgcagga tcaggatctggagatggagtccatgaaggctctggagaaactagtcaaaaggagacatcc acctgtgatatttgccagtttggtgcagaatgtgacgaagatgccgaggatgtctggtgt gtgtgtaatattgactgttctcaaaccaacttcaatcccctctgcgcttctgatgggaaa tcttatgataatgcatgccaaatcaaagaagcatcgtgtcagaaacaggagaaaattgaa gtcatgtctttgggtcgatgtcaagataacacaactacaactactaagtctgaagatggg cattatgcaagaacagattatgcagagaatgctaacaaattagaagaaagtgccagagaa caccacataccttgtccggaacattacaatggcttctgcatgcatgggaagtgtgagcat tctatcaatatgcaggagccatcttgcaggtgtgatgctggttatactggacaacactgt gaaaaaaaggactacagtgttctatacgttgttcccggtcctgtacgatttcagtatgtc ttaatcgcagctgtgattggaacaattcagattgctgtcatctgtgtggtggtcctctgc atcacaaggaaatgccccagaagcaacagaattcacagacagaagcaaaatacagggcac tacagttcagacaatacaacaagagcgtccacgaggttaatctaa |
Protein Sequence |
>23671 : length: 374 MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPTGWNCSGYD DRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAA CKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWC VCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDG HYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHC EKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGH YSSDNTTRASTRLI |