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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 26959 |
Name | HBP1 |
Synonym | -;HMG-box transcription factor 1;HBP1;HMG-box transcription factor 1 |
Definition | HMG box transcription factor 1|HMG box-containing protein 1|high mobility group box transcription factor 1 |
Position | 7q22-q31 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
reviewed | The tumor suppressor protein HBP1 is a novel c-myc-binding protein that negatively regulates c-myc transcriptional activity. |
potential | in myeloid cells HBP1 may serve as a tumor suppressor and a general differentiation inducer and may synergize with chemical differentiating agents to enhance lineage-specific differentiation. |
| More detail of all 2 literatures about HBP1 | |
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Pathways and Diseases |
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Pathway | Regulation of Wnt-mediated beta catenin signaling and target gene transcription;PID Curated;200106 |
Pathway | E2F transcription factor network;PID Curated;200027 |
Pathway | Signaling mediated by p38-alpha and p38-beta;PID Curated;200154 |
Pathway | C-MYC pathway;PID Curated;200093 |
Disease | Cancer;FunDO |
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External Links |
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Links to Entrez Gene | 26959 |
Links to all GeneRIF Items | 26959 |
Links to iHOP | 26959 |
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Sequence Information |
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Nucleotide Sequence |
>26959 : length: 1545 atggtgtgggaagtgaagacaaatcagatgcctaatgcagtacagaaactcctgttggtg atggacaagagagcctcaggaatgaatgactcattggagttgctgcagtgtaatgagaat ttgccatcttcacctggatataactcctgtgatgaacacatggagcttgatgaccttcct gaacttcaggcagttcaaagtgatcctacccaatctggcatgtaccagctgagttcagat gtttcacatcaagaatacccaagatcatcttggaaccaaaatacctcagacataccagaa actacttaccgtgaaaatgaggtggactggctaacagaattggcaaatatcgcgaccagt ccacaaagtccactgatgcagtgctcattttacaatagatcatctcctgtacacatcata gccactagcaaaagtttacattcctatgcacgccctccaccagtgtcctcttcttcgaag agtgaaccagccttccctcatcaccattggaaggaggaaacaccagtaagacacgaaagg gcaaatagtgagtcagaatctggcattttctgcatgtcctccctgtcagatgatgatgat ttgggatggtgcaattcctggccttcaactgtctggcactgttttttgaaaggcacacga ctgtgctttcataagggaagcaataaggaatggcaagatgttgaagattttgctagagct gaaggctgtgataatgaggaagatcttcaaatgggcattcacaagggctatggttctgat ggtctaaagttgttatcacatgaagaaagtgtatcatttggcgagtctgtactgaagttg acttttgatcctggtacagtagaagatggtttacttaccgtagagtgtaagctggaccac cctttctatgttaaaaataaaggttggtcatcattttatccaagcttgactgtggtacag catggcattccatgttgtgaagttcatattggcgatgtatgtctacctcctggacacccc gatgccattaattttgatgattcaggtgtttttgatacatttaaaagctatgacttcaca cctatggattcttctgcagtttatgtgttaagtagtatggctcgccagcgtcgtgcatct ttgtcttgtggaggacctggtggtcaagactttgcaagatctggattcagtaaaaactgt ggctcacctggatcatcacagctctcttccaattctttgtatgctaaagctgtcaaaaac cacagctcagggactgtgagtgccacttctcctaataagtgcaaaagaccaatgaatgcc ttcatgctttttgccaaaaaatacagagttgaatatactcagatgtatccagggaaagat aacagagccataagtgtgatccttggtgacaggtggaagaaaatgaagaatgaagagaga agaatgtacacattagaagcaaaggctttggctgaagaacagaaacgtttaaatcctgac tgttggaagaggaaaagaaccaattcaggctcacaacaacattaa |
Protein Sequence |
>26959 : length: 514 MVWEVKTNQMPNAVQKLLLVMDKRASGMNDSLELLQCNENLPSSPGYNSCDEHMELDDLP ELQAVQSDPTQSGMYQLSSDVSHQEYPRSSWNQNTSDIPETTYRENEVDWLTELANIATS PQSPLMQCSFYNRSSPVHIIATSKSLHSYARPPPVSSSSKSEPAFPHHHWKEETPVRHER ANSESESGIFCMSSLSDDDDLGWCNSWPSTVWHCFLKGTRLCFHKGSNKEWQDVEDFARA EGCDNEEDLQMGIHKGYGSDGLKLLSHEESVSFGESVLKLTFDPGTVEDGLLTVECKLDH PFYVKNKGWSSFYPSLTVVQHGIPCCEVHIGDVCLPPGHPDAINFDDSGVFDTFKSYDFT PMDSSAVYVLSSMARQRRASLSCGGPGGQDFARSGFSKNCGSPGSSQLSSNSLYAKAVKN HSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEER RMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH |