Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

27232

Name

GNMT

Synonym

-;glycine N-methyltransferase;GNMT;glycine N-methyltransferase

Definition

-

Position

6p12

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

reviewed

"GNMT is a tumor suppressor gene for liver cancer, and it is associated with gender disparity in liver cancer susceptibility as shown in humans and in mouse models".
More detail of all 1 literatures about GNMT

Pathways and Diseases

Pathway

Glycine, serine and threonine metabolism;KEGG PATHWAY;hsa00260

Disease

homocyteine;GAD

Disease

Glycine N-methyltransferase deficiency;OMIM

Disease

prostate cancer;GAD

Disease

CANCER;GAD

Disease

Liver disease;FunDO

Disease

METABOLIC;GAD

Disease

Liver cancer;FunDO

External Links

Links to Entrez Gene

27232

Links to all GeneRIF Items

27232

Links to iHOP

27232

Sequence Information

Nucleotide Sequence

>27232 : length: 888
atggtggacagcgtgtaccggacccgctccctgggggtggcggccgaagggctcccggac
cagtacgcggacggggaggcggcgcgcgtgtggcagctgtatatcggagacacccgcagc
cgcaccgccgagtacaaggcatggctgcttgggctgctgcgccagcacggctgccagcgg
gtgctcgacgtagcctgtggcactggggtggactccattatgctggtggaagagggcttc
agtgtgacgagtgtggatgccagtgacaagatgctgaagtatgcacttaaggagcgctgg
aaccggcggcacgagcccgccttcgacaagtgggtcatcgaagaagccaactggatgact
ctggacaaagatgtgccccagtcagcagagggtggctttgatgctgtcatctgccttgga
aacagtttcgctcacttgccagactgcaaaggggaccagagtgagcaccggctggcgctg
aaaaacattgcgagcatggtgcgggcagggggcctactggtcattgatcatcgcaactac
gaccacatcctcagtacaggctgtgcacccccagggaagaacatctactataagagtgac
ttgaccaaggacgtcacaacatcagtgctgatagtgaacaacaaggcccacatggtgacc
ctggactatacggtgcaggtgccgggggctggccaggatggctctcctggcttgagtaag
ttccggctctcctactacccacactgtctggcatccttcacggagctgctccaagcagcc
ttcggaggtaagtgccagcacagcgtcctgggcgacttcaagccttacaagccaggccaa
acctacattccctgctacttcatccacgtgctcaagaggacagactga

Protein Sequence

>27232 : length: 295
MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQR
VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMT
LDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNY
DHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSK
FRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD



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