Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

2878

Name

GPX3

Synonym

GPx-P|GSHPx-3|GSHPx-P;glutathione peroxidase 3 (plasma);GPX3;glutathione peroxidase 3 (plasma)

Definition

GPx-3|extracellular glutathione peroxidase|glutathione peroxidase 3|plasma glutathione peroxidase

Position

5q23

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

reviewed

The tumor suppressor activity of GPx3 seems to relate to its ability to suppress the expression of c-met.

reviewed

GPx3 is a novel tumor suppressor gene.
More detail of all 1 literatures about GPX3

Pathways and Diseases

Pathway

glutathione redox reactions I;BioCyc;PWY-4081

Pathway

Glutathione metabolism;KEGG PATHWAY;hsa00480

Pathway

Arachidonic acid metabolism;KEGG PATHWAY;hsa00590

Disease

CARDIOVASCULAR;GAD

Disease

stroke, ischemic;GAD

External Links

Links to Entrez Gene

2878

Links to all GeneRIF Items

2878

Links to iHOP

2878

Sequence Information

Nucleotide Sequence

>2878 : length: 681
atggcccggctgctgcaggcgtcctgcctgctttccctgctcctggccggcttcgtctcg
cagagccggggacaagagaagtcgaagatggactgccatggtggcataagtggcaccatt
tacgagtacggagccctcaccattgatggggaggagtacatccccttcaagcagtatgct
ggcaaatacgtcctctttgtcaacgtggccagctactgaggcctgacgggccagtacatt
gaactgaatgcactacaggaagagcttgcaccattcggtctggtcattctgggctttccc
tgcaaccaatttggaaaacaggaaccaggagagaactcagagatccttcctaccctcaag
tatgtccgaccaggtggaggctttgtccctaatttccagctctttgagaaaggggatgtc
aatggagagaaagagcagaaattctacactttcctaaagaactcctgtcctcccacctcg
gagctcctgggtacatctgaccgcctcttctgggaacccatgaaggttcacgacatccgc
tggaactttgagaagttcctggtggggccagatggtatacccatcatgcgctggcaccac
cggaccacggtcagcaacgtcaagatggacatcctgtcctacatgaggcggcaggcagcc
ctgggggtcaagaggaagtaa

Protein Sequence

>2878 : length: 226
MARLLQASCLLSLLLAGFVSQSRGQEKSKMDCHGGISGTIYEYGALTIDGEEYIPFKQYA
GKYVLFVNVASYUGLTGQYIELNALQEELAPFGLVILGFPCNQFGKQEPGENSEILPTLK
YVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTSELLGTSDRLFWEPMKVHDIR
WNFEKFLVGPDGIPIMRWHHRTTVSNVKMDILSYMRRQAALGVKRK



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