Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

2972

Name

BRF1

Synonym

BRF|BRF-1|GTF3B|TAF3B2|TAF3C|TAFIII90|TF3B90|TFIIIB90|hBRF;BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae);BRF1;BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)

Definition

B - related factor 1|TATA box binding protein (TBP)-associated factor 3C|TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2|TBP - associated factor, RNA polymerase III, 90kD|general transcription factor IIIB, 90kD subuni

Position

14q

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

potential

Brf1 gene was identified in the genome-wide loss-of-function genetic screen as putative tumor suppressor located at 14q32.33.
More detail of all 1 literatures about BRF1

Pathways and Diseases

Pathway

General transcription regulation;PANTHER;P00023

Pathway

Transcription regulation by bZIP transcription factor;PANTHER;P00055

Pathway

Transcription;Reactome;REACT:1788

Pathway

rna polymerase iii transcription;PID BioCarta;100039

External Links

Links to Entrez Gene

2972

Links to all GeneRIF Items

2972

Links to iHOP

2972

Sequence Information

Nucleotide Sequence

>2972 : length: 2034
atgacgggccgcgtgtgccgcggttgcggcggcacggacatcgagctggacgcggcgcgc
ggggacgcggtgtgcaccgcctgcggctcagtgctggaggacaacatcatcgtgtccgag
gtgcagttcgtggagagcagcggcggcggctcctcggccgtgggccagttcgtgtccctg
gacggtgctggcaaaaccccgactctgggtggcggcttccacgtgaatctggggaaggag
tcgagagcgcagaccctgcagaatgggaggcgccacatccaccacctggggaaccagctg
cagctgaaccagcactgcctggacaccgccttcaacttcttcaagatggccgtgagcagg
cacctgacccgcggccggaagatggcccacgtgattgctgcctgcctctacctggtctgc
cgtacggagggcacgccgcacatgctcctggacctcagcgacctgctccaggtgaatgtg
tacgtgcttggaaagacgtttcttctcttggcaagagagctctgcatcaatgcgccggcc
atagacccgtgcctgtatattccacgctttgcgcacctgctggaattcggggagaagaac
cacgaggtgtccatgactgccctgaggctcctacagaggatgaagcgggactggatgcac
acaggccggcgcccctcgggcctctgcggagcagcgctcctggttgcagccagaatgcat
gacttcaggaggactgtgaaggaggtcatcagtgtggtcaaagtgtgtgagtccacgctg
cggaagaggctcacggaatttgaagacacccccaccagtcagttgaccattgatgagttc
atgaagatcgacctggaggaggagtgcgaccccccctcgtacacagctgggcagaggaag
ctgcggatgaagcagcttgaacaagtcctgtcaaaaaaactggaggaggttgaaggtgaa
atatccagttaccaggatgcaattgagattgaactagaaaacagccggccaaaggccaag
gggggcctggccagcctggcaaaagatggctccaccgaggacaccgcgtccagcttgtgt
ggcgaggaggacacagaggacgaggagctggaagccgcggccagccacctgaacaaagac
ttataccgggagctccttggtggtgcccccggcagctcggaagcagcaggaagccccgag
tggggcggcagacctccggccctggggtccctgctggaccccctccccactgcagccagc
ctgggcatctcagactccatccgcgaatgcatctcctctcagagcagcgaccccaaagat
gcttcaggagacggtgagctggacctcagtggcattgatgacctggagattgacaggtac
atcctgaatgagtcggaagcccgcgtgaaggccgagctgtggatgagggagaacgccgag
tacctgcgggaacagagggaaaaagaagcaagaatagcgaaagagaaggagctcggcatc
tacaaggaacacaagcccaagaagtcttgcaagcgacgggagccaattcaggccagtacc
gccagggaggccatcgagaagatgctggagcagaagaagatctccagcaagatcaattat
agcgtgctccggggcctcagcagcgccggcgggggcagtccgcacagggaggatgcacag
cccgagcatagcgccagtgccaggaagctgtcacgaaggaggacgccggccagcagaagt
ggggctgaccctgtgaccagtgtggggaaaaggttgaggcctctggtgtctacgcagcca
gcaaagaaggtggccacgggagaggctttgctcccaagctctcccaccctcggagctgag
cctgccaggccccaggcggtgctggtggagagcgggcccgtgtcataccacgccgacgag
gaggctgacgaggaggagcctgacgaggaggacggggagccctgcgtcagtgccctgcag
atgatgggcagcaacgactatggctgtgatggcgatgaggacgacggctactga

Protein Sequence

>2972 : length: 677
MTGRVCRGCGGTDIELDAARGDAVCTACGSVLEDNIIVSEVQFVESSGGGSSAVGQFVSL
DGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGNQLQLNQHCLDTAFNFFKMAVSR
HLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPA
IDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMH
DFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRK
LRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGGLASLAKDGSTEDTASSLC
GEEDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGSPEWGGRPPALGSLLDPLPTAAS
LGISDSIRECISSQSSDPKDASGDGELDLSGIDDLEIDRYILNESEARVKAELWMRENAE
YLREQREKEARIAKEKELGIYKEHKPKKSCKRREPIQASTAREAIEKMLEQKKISSKINY
SVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQP
AKKVATGEALLPSSPTLGAEPARPQAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQ
MMGSNDYGCDGDEDDGY



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