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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 29997 |
Name | GLTSCR2 |
Synonym | PICT-1|PICT1;glioma tumor suppressor candidate region gene 2;GLTSCR2;glioma tumor suppressor candidate region gene 2 |
Definition | glioma tumor suppressor candidate region gene 2 protein|p60|protein interacting with carboxyl terminus 1 |
Position | 19q13.3 |
Gene Type | protein-coding |
Source | Count: 3; Pubmed_search,TAG,Generif |
Literature support | Count: 5 PubMed records as below. |
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Evidence Status |
Description |
potential | "The expression of GLTSCR2, a candidate tumor suppressor, is reduced in seborrheic keratosis compared to normal skin." |
potential | "study describes a novel interaction between KS-Bcl-2 & PICT-1 cellular protein, encoded by a candidate tumor suppressor gene, GLTSCR2; show this interaction specifically targets KS-Bcl-2 to the nucleolus & decreases its antiapoptotic activity". |
potential | The putative tumor suppressor gene GLTSCR2 induces PTEN-modulated cell death. |
potential | "Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation." |
potential | Regulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein. |
| More detail of all 5 literatures about GLTSCR2 | |
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External Links |
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Links to Entrez Gene | 29997 |
Links to all GeneRIF Items | 29997 |
Links to iHOP | 29997 |
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Sequence Information |
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Nucleotide Sequence |
>29997 : length: 1437 atggcggcaggaggcagtggcgttggtgggaagcgcagctcgaaaagcgatgccgattct ggtttcctggggctgcggcccacttcggtggacccagcgctgaggcggcggcggcgaggc ccaagaaataagaagcggggctggcggcggcttgctcaggagccgctggggctggaggtt gaccagttcctggaagacgtgcggctacaggagcgcacgagcggtggcttgttgtcagag gccccaaatgaaaaactcttcttcgtggacactggctccaaggaaaaagggctgacaaag aagagaaccaaagtccagaagaagtcactgcttctcaagaaaccccttcgggttgacctc atcctcgagaacacatccaaagtccctgcccccaaagacgtcctcgcccaccaggtcccc aacgccaagaagctcaggcggaaggagcagctatgggagaagctggccaagcagggcgag ctgccccgggaggtgcgcagggcccaggcccggctcctcaacccttctgcaacaagggcc aagcccgggccccaggacaccgtagagcggcccttctacgacctctgggcctcagacaac cccctggacaggccgttggttggccaggatgagtttttcctggagcagaccaagaagaaa ggagtgaagcggccagcacgcctgcacaccaagccgtcccaggcacccgccgtggaggtg gcgcctgccggagcttcctacaatccatcctttgaagaccaccagaccctgctctcagcg gcccacgaggtggagttgcagcggcagaaggaggcggagaagctggagcggcagctggcc ctgcccgccacggagcaggccgccacccaggagtccacattccaggagctgtgcgagggg ctgctggaggagtcggatggtgagggggagccaggccagggcgaggggccggaggctggg gatgccgaggtctgtcccacgcccgcccgcctggccaccacagagaagaagacggagcag cagcggcggcgggagaaggctgtgcacaggctgcgggtacagcaggccgcgttgcgggcc gcccggctccggcaccaggagctgttccggctgcgcgggatcaaggcccaggtggccctg aggctggcggagctggcgcggcggcagaggcggcggcaggcgcggcgggaggctgaggct gacaagccccgaaggctggggcggctcaagtaccaggcacctgacatcgacgtgcagctg agctcggagctgacagactcgctcaggaccctgaagcccgagggcaacatccttcgagac cggttcaagagcttccagaggaggaatatgatcgagcctcgagagagagccaagttcaaa cgcaagtacaaggtgaagctggtggagaagcgggcgttccgtgagatccagttgtag |
Protein Sequence |
>29997 : length: 478 MAAGGSGVGGKRSSKSDADSGFLGLRPTSVDPALRRRRRGPRNKKRGWRRLAQEPLGLEV DQFLEDVRLQERTSGGLLSEAPNEKLFFVDTGSKEKGLTKKRTKVQKKSLLLKKPLRVDL ILENTSKVPAPKDVLAHQVPNAKKLRRKEQLWEKLAKQGELPREVRRAQARLLNPSATRA KPGPQDTVERPFYDLWASDNPLDRPLVGQDEFFLEQTKKKGVKRPARLHTKPSQAPAVEV APAGASYNPSFEDHQTLLSAAHEVELQRQKEAEKLERQLALPATEQAATQESTFQELCEG LLEESDGEGEPGQGEGPEAGDAEVCPTPARLATTEKKTEQQRRREKAVHRLRVQQAALRA ARLRHQELFRLRGIKAQVALRLAELARRQRRRQARREAEADKPRRLGRLKYQAPDIDVQL SSELTDSLRTLKPEGNILRDRFKSFQRRNMIEPRERAKFKRKYKVKLVEKRAFREIQL |