Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

3164

Name

NR4A1

Synonym

GFRP1|HMR|N10|NAK-1|NGFIB|NP10|NUR77|TR3;nuclear receptor subfamily 4, group A, member 1;NR4A1;nuclear receptor subfamily 4, group A, member 1

Definition

ST-59|TR3 orphan receptor|early response protein NAK1|growth factor-inducible nuclear protein N10|hormone receptor|nerve growth factor IB nuclear receptor variant 1|nuclear hormone receptor NUR/77|nuclear receptor subfamily 4 group A member 1|orphan nucle

Position

12q13

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

reviewed

NUR77 is a critical tumor suppressor of myeloid leukemogenesis that is downregulated in leukemic blasts from acute myeloid leukemia patients.
More detail of all 1 literatures about NR4A1

Pathways and Diseases

Pathway

Glucocorticoid receptor regulatory network;PID Curated;200077

Pathway

RXR and RAR heterodimerization with other nuclear receptor;PID Curated;200112

Pathway

Role of Calcineurin-dependent NFAT signaling in lymphocytes;PID Curated;200076

Pathway

MAPK signaling pathway;KEGG PATHWAY;hsa04010

Pathway

AKT phosphorylates targets in the nucleus;PID Reactome;500641

Pathway

role of mef2d in t-cell apoptosis;PID BioCarta;100109

Pathway

Signalling by NGF;Reactome;REACT:11061

Pathway

Gene Expression;Reactome;REACT:71

External Links

Links to Entrez Gene

3164

Links to all GeneRIF Items

3164

Links to iHOP

3164

Sequence Information

Nucleotide Sequence

>3164 : length: 1836
atgtggttggccaaggcctgttggtccatccagagtgagatgccctgtatccaagcccaa
tatgggacaccagcaccgagtccgggaccccgtgaccacctggcaagcgaccccctgacc
cctgagttcatcaagcccaccatggacctggccagccccgaggcagcccccgctgccccc
actgccctgcccagcttcagcaccttcatggacggctacacaggagagtttgacaccttc
ctctaccagctgccaggaacagtccagccatgctcctcagcctcctcctcggcctcctcc
acatcctcgtcctcagccacctcccctgcctctgcctccttcaagttcgaggacttccag
gtgtacggctgctaccccggccccctgagcggcccagtggatgaggccctgtcctccagt
ggctctgactactatggcagcccctgctcggccccgtcgccctccacgcccagcttccag
ccgccccagctctctccctgggatggctccttcggccacttctcgcccagccagacttac
gaaggcctgcgggcatggacagagcagctgcccaaagcctctgggcccccacagcctcca
gccttcttttccttcagtcctcccaccggccccagccccagcctggcccagagccccctg
aagttgttcccctcacaggccacccaccagctgggggagggagagagctattccatgcct
acggccttcccaggtttggcacccacttctccacaccttgagggctcggggatactggat
acacccgtgacctcaaccaaggcccggagcggggccccaggtggaagtgaaggccgctgt
gctgtgtgtggggacaacgcttcatgccagcattatggtgtccgcacatgtgagggctgc
aagggcttcttcaagcgcacagtgcagaaaaacgccaagtacatctgcctggctaacaag
gactgccctgtggacaagaggcggcgaaaccgctgccagttctgccgcttccagaagtgc
ctggcggtgggcatggtgaaggaagttgtccgaacagacagcctgaaggggcggcggggc
cggctaccttcaaaacccaagcagcccccagatgcctcccctgccaatctcctcacttcc
ctggtccgtgcacacctggactcagggcccagcactgccaaactggactactccaagttc
caggagctggtgctgccccactttgggaaggaagatgctggggatgtacagcagttctac
gacctgctctccggttctctggaggtcatccgcaagtgggcggagaagatccctggcttt
gctgagctgtcaccggctgaccaggacctgttgctggagtcggccttcctggagctcttc
atcctccgcctggcgtacaggtctaagccaggcgagggcaagctcatcttctgctcaggc
ctggtgctacaccggctgcagtgtgcccgtggcttcggggactggattgacagtatcctg
gccttctcaaggtccctgcacagcttgcttgtcgatgtccctgccttcgcctgcctctct
gcccttgtcctcatcaccgaccggcatgggctgcaggagccgcggcgggtggaggagctg
cagaaccgcatcgccagctgcctgaaggagcacgtggcagctgtggcgggcgagccccag
ccagccagctgcctgtcacgtctgttgggcaaactgcccgagctgcggaccctgtgcacc
cagggcctgcagcgcatcttctacctcaagctggaggacttggtgccccctccacccatc
attgacaagatcttcatggacacgctgcccttctga

Protein Sequence

>3164 : length: 611
MWLAKACWSIQSEMPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAP
TALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQ
VYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTY
EGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMP
TAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGC
KGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRG
RLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFY
DLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSG
LVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEEL
QNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPI
IDKIFMDTLPF



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