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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 3164 |
Name | NR4A1 |
Synonym | GFRP1|HMR|N10|NAK-1|NGFIB|NP10|NUR77|TR3;nuclear receptor subfamily 4, group A, member 1;NR4A1;nuclear receptor subfamily 4, group A, member 1 |
Definition | ST-59|TR3 orphan receptor|early response protein NAK1|growth factor-inducible nuclear protein N10|hormone receptor|nerve growth factor IB nuclear receptor variant 1|nuclear hormone receptor NUR/77|nuclear receptor subfamily 4 group A member 1|orphan nucle |
Position | 12q13 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
reviewed | NUR77 is a critical tumor suppressor of myeloid leukemogenesis that is downregulated in leukemic blasts from acute myeloid leukemia patients. |
| More detail of all 1 literatures about NR4A1 | |
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Pathways and Diseases |
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Pathway | Glucocorticoid receptor regulatory network;PID Curated;200077 |
Pathway | RXR and RAR heterodimerization with other nuclear receptor;PID Curated;200112 |
Pathway | Role of Calcineurin-dependent NFAT signaling in lymphocytes;PID Curated;200076 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | AKT phosphorylates targets in the nucleus;PID Reactome;500641 |
Pathway | role of mef2d in t-cell apoptosis;PID BioCarta;100109 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Gene Expression;Reactome;REACT:71 |
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External Links |
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Links to Entrez Gene | 3164 |
Links to all GeneRIF Items | 3164 |
Links to iHOP | 3164 |
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Sequence Information |
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Nucleotide Sequence |
>3164 : length: 1836 atgtggttggccaaggcctgttggtccatccagagtgagatgccctgtatccaagcccaa tatgggacaccagcaccgagtccgggaccccgtgaccacctggcaagcgaccccctgacc cctgagttcatcaagcccaccatggacctggccagccccgaggcagcccccgctgccccc actgccctgcccagcttcagcaccttcatggacggctacacaggagagtttgacaccttc ctctaccagctgccaggaacagtccagccatgctcctcagcctcctcctcggcctcctcc acatcctcgtcctcagccacctcccctgcctctgcctccttcaagttcgaggacttccag gtgtacggctgctaccccggccccctgagcggcccagtggatgaggccctgtcctccagt ggctctgactactatggcagcccctgctcggccccgtcgccctccacgcccagcttccag ccgccccagctctctccctgggatggctccttcggccacttctcgcccagccagacttac gaaggcctgcgggcatggacagagcagctgcccaaagcctctgggcccccacagcctcca gccttcttttccttcagtcctcccaccggccccagccccagcctggcccagagccccctg aagttgttcccctcacaggccacccaccagctgggggagggagagagctattccatgcct acggccttcccaggtttggcacccacttctccacaccttgagggctcggggatactggat acacccgtgacctcaaccaaggcccggagcggggccccaggtggaagtgaaggccgctgt gctgtgtgtggggacaacgcttcatgccagcattatggtgtccgcacatgtgagggctgc aagggcttcttcaagcgcacagtgcagaaaaacgccaagtacatctgcctggctaacaag gactgccctgtggacaagaggcggcgaaaccgctgccagttctgccgcttccagaagtgc ctggcggtgggcatggtgaaggaagttgtccgaacagacagcctgaaggggcggcggggc cggctaccttcaaaacccaagcagcccccagatgcctcccctgccaatctcctcacttcc ctggtccgtgcacacctggactcagggcccagcactgccaaactggactactccaagttc caggagctggtgctgccccactttgggaaggaagatgctggggatgtacagcagttctac gacctgctctccggttctctggaggtcatccgcaagtgggcggagaagatccctggcttt gctgagctgtcaccggctgaccaggacctgttgctggagtcggccttcctggagctcttc atcctccgcctggcgtacaggtctaagccaggcgagggcaagctcatcttctgctcaggc ctggtgctacaccggctgcagtgtgcccgtggcttcggggactggattgacagtatcctg gccttctcaaggtccctgcacagcttgcttgtcgatgtccctgccttcgcctgcctctct gcccttgtcctcatcaccgaccggcatgggctgcaggagccgcggcgggtggaggagctg cagaaccgcatcgccagctgcctgaaggagcacgtggcagctgtggcgggcgagccccag ccagccagctgcctgtcacgtctgttgggcaaactgcccgagctgcggaccctgtgcacc cagggcctgcagcgcatcttctacctcaagctggaggacttggtgccccctccacccatc attgacaagatcttcatggacacgctgcccttctga |
Protein Sequence |
>3164 : length: 611 MWLAKACWSIQSEMPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAP TALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQ VYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTY EGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMP TAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGC KGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRG RLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFY DLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSG LVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEEL QNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPI IDKIFMDTLPF |