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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 3170 |
Name | FOXA2 |
Synonym | HNF3B|TCF3B;forkhead box A2;FOXA2;forkhead box A2 |
Definition | HNF-3-beta|HNF-3B|TCF-3B|forkhead box protein A2|hepatic nuclear factor-3-beta|hepatocyte nuclear factor 3, beta|hepatocyte nuclear factor 3-beta|transcription factor 3B |
Position | 20p11 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
reviewed | "Expression of HNF3 beta led to significant growth reduction, proliferation arrest, apoptosis, and loss of clonogenic ability, suggesting additionally that HNF3 beta is a novel tumor suppressor in lung cancer." |
| More detail of all 1 literatures about FOXA2 | |
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Pathways and Diseases |
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Pathway | FOXA1 transcription factor network;PID Curated;200194 |
Pathway | Hedgehog signaling events mediated by Gli proteins;PID Curated;200147 |
Pathway | Maturity onset diabetes of the young;KEGG PATHWAY;hsa04950 |
Pathway | FOXA transcription factor networks;PID Curated;200163 |
Pathway | FOXA2 and FOXA3 transcription factor networks;PID Curated;200073 |
Pathway | Regulation of gene expression in beta cells;PID Reactome;500522 |
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External Links |
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Links to Entrez Gene | 3170 |
Links to all GeneRIF Items | 3170 |
Links to iHOP | 3170 |
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Sequence Information |
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Nucleotide Sequence |
>3170 : length: 1392 atgcactcggcttccagtatgctgggagcggtgaagatggaagggcacgagccgtccgac tggagcagctactatgcagagcccgagggctactcctccgtgagcaacatgaacgccggc ctggggatgaacggcatgaacacgtacatgagcatgtcggcggccgccatgggcagcggc tcgggcaacatgagcgcgggctccatgaacatgtcgtcgtacgtgggcgctggcatgagc ccgtccctggcggggatgtcccccggcgcgggcgccatggcgggcatgggcggctcggcc ggggcggccggcgtggcgggcatggggccgcacttgagtcccagcctgagcccgctcggg gggcaggcggccggggccatgggcggcctggccccctacgccaacatgaactccatgagc cccatgtacgggcaggcgggcctgagccgcgcccgcgaccccaagacctacaggcgcagc tacacgcacgcaaagccgccctactcgtacatctcgctcatcaccatggccatccagcag agccccaacaagatgctgacgctgagcgagatctaccagtggatcatggacctcttcccc ttctaccggcagaaccagcagcgctggcagaactccatccgccactcgctctccttcaac gactgtttcctgaaggtgccccgctcgcccgacaagcccggcaagggctccttctggacc ctgcaccctgactcgggcaacatgttcgagaacggctgctacctgcgccgccagaagcgc ttcaagtgcgagaagcagctggcgctgaaggaggccgcaggcgccgccggcagcggcaag aaggcggccgccggagcccaggcctcacaggctcaactcggggaggccgccgggccggcc tccgagactccggcgggcaccgagtcgcctcactcgagcgcctccccgtgccaggagcac aagcgagggggcctgggagagctgaaggggacgccggctgcggcgctgagccccccagag ccggcgccctctcccgggcagcagcagcaggccgcggcccacctgctgggcccgccccac cacccgggcctgccgcctgaggcccacctgaagccggaacaccactacgccttcaaccac ccgttctccatcaacaacctcatgtcctcggagcagcagcaccaccacagccaccaccac caccaaccccacaaaatggacctcaaggcctacgaacaggtgatgcactaccccggctac ggttcccccatgcctggcagcttggccatgggcccggtcacgaacaaaacgggcctggac gcctcgcccctggccgcagatacctcctactaccagggggtgtactcccggcccattatg aactcctcttaa |
Protein Sequence |
>3170 : length: 463 MHSASSMLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNAGLGMNGMNTYMSMSAAAMGSG SGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLG GQAAGAMGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQ SPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWT LHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPA SETPAGTESPHSSASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGPPH HPGLPPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGY GSPMPGSLAMGPVTNKTGLDASPLAADTSYYQGVYSRPIMNSS |