Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

3175

Name

ONECUT1

Synonym

HNF-6|HNF6|HNF6A;one cut homeobox 1;ONECUT1;one cut homeobox 1

Definition

hepatocyte nuclear factor 6|hepatocyte nuclear factor 6, alpha|one cut domain family member 1|one cut domain, family member 1

Position

15q21.3

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

potential

"ONECUT1 expression is lost in pancreatic cancer cells, suggesting a tumor suppressor function in this malignancy."
More detail of all 1 literatures about ONECUT1

Pathways and Diseases

Pathway

Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells;PID Reactome;500520

Pathway

Regulation of beta-cell development;PID Reactome;500518

Pathway

Maturity onset diabetes of the young;KEGG PATHWAY;hsa04950

Pathway

FOXM1 transcription factor network;PID Curated;200120

Pathway

Regulation of beta-cell development;Reactome;REACT:13698

Pathway

Regulation of gene expression in early pancreatic precursor cells;PID Reactome;500519

Disease

Cancer;FunDO

External Links

Links to Entrez Gene

3175

Links to all GeneRIF Items

3175

Links to iHOP

3175

Sequence Information

Nucleotide Sequence

>3175 : length: 1398
atgaacgcgcagctgaccatggaagcgatcggcgagctgcacggggtgagccatgagccg
gtgcccgcccctgccgacctgctgggcggcagcccccacgcgcgcagctccgtggcgcac
cgcggcagccacctgccccccgcgcacccgcgctccatgggcatggcgtccctgctggac
ggcggcagcggcggcggagattaccaccaccaccaccgggcccctgagcacagcctggcc
ggccccctgcatcccaccatgaccatggcctgcgagactcccccaggtatgagcatgccc
accacctacaccaccttgacccctctgcagccgctgcctcccatctccacagtctcggac
aagttcccccaccatcaccaccaccaccatcaccaccaccacccgcaccaccaccagcgc
ctggcgggcaacgtgagcggtagcttcacgctcatgcgggatgagcgcgggctggcctcc
atgaataacctctataccccctaccacaaggacgtggccggcatgggccagagcctctcg
cccctctccagctccggtctgggcagcatccacaactcccagcaagggctcccccactat
gcccacccgggggccgccatgcccaccgacaagatgctcacccccaacggcttcgaagcc
caccacccggccatgctcggccgccacggggagcagcacctcacgcccacctcggccggc
atggtgcccatcaacggccttcctccgcaccatccccacgcccacctgaacgcccagggc
cacgggcaactcctgggcacagcccgggagcccaacccttcggtgaccggcgcgcaggtc
agcaatggaagtaattcagggcagatggaagagatcaataccaaagaggtggcgcagcgt
atcaccaccgagctcaagcgctacagcatcccacaggccatcttcgcgcagagggtgctc
tgccgctcccaggggaccctctcggacctgctgcgcaaccccaaaccctggagcaaactc
aaatccggccgggagaccttccggaggatgtggaagtggctgcaggagccggagttccag
cgcatgtccgcgctccgcttagcagcatgcaaaaggaaagaacaagaacatgggaaggat
agaggcaacacacccaaaaagcccaggttggtcttcacagatgtccagcgtcgaactcta
catgcaatattcaaggaaaataagcgtccatccaaagaattgcaaatcaccatttcccag
cagctggggttggagctgagcactgtcagcaacttcttcatgaacgcaagaaggaggagt
ctggacaagtggcaggacgagggcagctccaattcaggcaactcatcttcttcatcaagc
acttgtaccaaagcatga

Protein Sequence

>3175 : length: 465
MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLD
GGSGGGDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSD
KFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLS
PLSSSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAG
MVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQR
ITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQ
RMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQ
QLGLELSTVSNFFMNARRRSLDKWQDEGSSNSGNSSSSSSTCTKA



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