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| General information | Expression | Regulation | Mutation | Interaction |
Basic Information | |
|---|---|
Gene ID | 3175 |
Name | ONECUT1 |
Synonym | HNF-6|HNF6|HNF6A;one cut homeobox 1;ONECUT1;one cut homeobox 1 |
Definition | hepatocyte nuclear factor 6|hepatocyte nuclear factor 6, alpha|one cut domain family member 1|one cut domain, family member 1 |
Position | 15q21.3 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
Evidence Status | Description |
potential | "ONECUT1 expression is lost in pancreatic cancer cells, suggesting a tumor suppressor function in this malignancy." |
| More detail of all 1 literatures about ONECUT1 | |
Pathways and Diseases | |
Pathway | Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells;PID Reactome;500520 |
Pathway | Regulation of beta-cell development;PID Reactome;500518 |
Pathway | Maturity onset diabetes of the young;KEGG PATHWAY;hsa04950 |
Pathway | FOXM1 transcription factor network;PID Curated;200120 |
Pathway | Regulation of beta-cell development;Reactome;REACT:13698 |
Pathway | Regulation of gene expression in early pancreatic precursor cells;PID Reactome;500519 |
Disease | Cancer;FunDO |
External Links | |
Links to Entrez Gene | 3175 |
Links to all GeneRIF Items | 3175 |
Links to iHOP | 3175 |
Sequence Information | |
Nucleotide Sequence | >3175 : length: 1398 atgaacgcgcagctgaccatggaagcgatcggcgagctgcacggggtgagccatgagccg gtgcccgcccctgccgacctgctgggcggcagcccccacgcgcgcagctccgtggcgcac cgcggcagccacctgccccccgcgcacccgcgctccatgggcatggcgtccctgctggac ggcggcagcggcggcggagattaccaccaccaccaccgggcccctgagcacagcctggcc ggccccctgcatcccaccatgaccatggcctgcgagactcccccaggtatgagcatgccc accacctacaccaccttgacccctctgcagccgctgcctcccatctccacagtctcggac aagttcccccaccatcaccaccaccaccatcaccaccaccacccgcaccaccaccagcgc ctggcgggcaacgtgagcggtagcttcacgctcatgcgggatgagcgcgggctggcctcc atgaataacctctataccccctaccacaaggacgtggccggcatgggccagagcctctcg cccctctccagctccggtctgggcagcatccacaactcccagcaagggctcccccactat gcccacccgggggccgccatgcccaccgacaagatgctcacccccaacggcttcgaagcc caccacccggccatgctcggccgccacggggagcagcacctcacgcccacctcggccggc atggtgcccatcaacggccttcctccgcaccatccccacgcccacctgaacgcccagggc cacgggcaactcctgggcacagcccgggagcccaacccttcggtgaccggcgcgcaggtc agcaatggaagtaattcagggcagatggaagagatcaataccaaagaggtggcgcagcgt atcaccaccgagctcaagcgctacagcatcccacaggccatcttcgcgcagagggtgctc tgccgctcccaggggaccctctcggacctgctgcgcaaccccaaaccctggagcaaactc aaatccggccgggagaccttccggaggatgtggaagtggctgcaggagccggagttccag cgcatgtccgcgctccgcttagcagcatgcaaaaggaaagaacaagaacatgggaaggat agaggcaacacacccaaaaagcccaggttggtcttcacagatgtccagcgtcgaactcta catgcaatattcaaggaaaataagcgtccatccaaagaattgcaaatcaccatttcccag cagctggggttggagctgagcactgtcagcaacttcttcatgaacgcaagaaggaggagt ctggacaagtggcaggacgagggcagctccaattcaggcaactcatcttcttcatcaagc acttgtaccaaagcatga |
Protein Sequence | >3175 : length: 465 MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLD GGSGGGDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSD KFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLS PLSSSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAG MVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQR ITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQ RMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQ QLGLELSTVSNFFMNARRRSLDKWQDEGSSNSGNSSSSSSTCTKA |