Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

3400

Name

ID4

Synonym

IDB4|bHLHb27;inhibitor of DNA binding 4, dominant negative helix-loop-helix protein;ID4;inhibitor of DNA binding 4, dominant negative helix-loop-helix protein

Definition

DNA-binding protein inhibitor ID-4|class B basic helix-loop-helix protein 27

Position

6p22.3

Gene Type

protein-coding

Source

Count: 2; Pubmed_search,Generif

Literature support

Count: 2 PubMed records as below.

Evidence Status

Description

potential

Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia.

potential

ID4 gene is a potential tumor suppressor gene for which methylation status may play an important role in the CRC progression.
More detail of all 2 literatures about ID4

Pathways and Diseases

Pathway

TGF-beta signaling pathway;KEGG PATHWAY;hsa04350

Disease

Rett syndrome;FunDO

Disease

Cancer;FunDO

Disease

CHEMDEPENDENCY;GAD

Disease

alcohol dependence;GAD

External Links

Links to Entrez Gene

3400

Links to all GeneRIF Items

3400

Links to iHOP

3400

Sequence Information

Nucleotide Sequence

>3400 : length: 486
atgaaggcggtgagcccggtgcgcccctcgggccgcaaggcgccgtcgggctgcggcggc
ggggagctggcgctgcgctgcctggccgagcacggccacagcctgggtggctccgcagcc
gcggcggcggcggcggcggcagcgcgctgtaaggcggccgaggcggcggccgacgagccg
gcgctgtgcctgcagtgcgatatgaacgactgctatagccgcctgcggaggctggtgccc
accatcccgcccaacaagaaagtcagcaaagtggagatcctgcagcacgttatcgactac
atcctggacctgcagctggcgctggagacgcacccggccctgctgaggcagccaccaccg
cccgcgccgccacaccacccggccgggacctgtccagccgcgccgccgcggaccccgctc
actgcgctcaacaccgacccggccggcgcggtgaacaagcagggcgacagcattctgtgc
cgctga

Protein Sequence

>3400 : length: 161
MKAVSPVRPSGRKAPSGCGGGELALRCLAEHGHSLGGSAAAAAAAAAARCKAAEAAADEP
ALCLQCDMNDCYSRLRRLVPTIPPNKKVSKVEILQHVIDYILDLQLALETHPALLRQPPP
PAPPHHPAGTCPAAPPRTPLTALNTDPAGAVNKQGDSILCR



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