|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3490 |
Name | IGFBP7 |
Synonym | AGM|FSTL2|IBP-7|IGFBP-7|IGFBP-7v|IGFBPRP1|MAC25|PSF|RAMSVPS|TAF;insulin-like growth factor binding protein 7;IGFBP7;insulin-like growth factor binding protein 7 |
Definition | IGF-binding protein 7|IGFBP-rP1|PGI2-stimulating factor|angiomodulin|insulin-like growth factor-binding protein 7|prostacyclin-stimulating factor|tumor-derived adhesion factor |
Position | 4q12 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 4 PubMed records as below. |
|
Evidence Status |
Description |
potential | Insulin-like growth factor-binding protein-7 functions as a potential tumor suppressor in hepatocellular carcinoma. |
potential | IGFBP7 plays a potential tumor suppressor role in colorectal carcinogenesis. |
potential | IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis and its expression is associated with DNA hypomethylation of exon 1. |
reviewed | "A secreted tumor-suppressor, mac25, with activin-binding activity." |
| More detail of all 4 literatures about IGFBP7 | |
|
External Links |
|
Links to Entrez Gene | 3490 |
Links to all GeneRIF Items | 3490 |
Links to iHOP | 3490 |
|
Sequence Information |
|
Nucleotide Sequence |
>3490 : length: 849 atggagcggccgtcgctgcgcgccctgctcctcggcgccgctgggctgctgctcctgctc ctgcccctctcctcttcctcctcttcggacacctgcggcccctgcgagccggcctcctgc ccgcccctgcccccgctgggctgcctgctgggcgagacccgcgacgcgtgcggctgctgc cctatgtgcgcccgcggcgagggcgagccgtgcgggggtggcggcgccggcagggggtac tgcgcgccgggcatggagtgcgtgaagagccgcaagaggcggaagggtaaagccggggca gcagccggcggtccgggtgtaagcggcgtgtgcgtgtgcaagagccgctacccggtgtgc ggcagcgacggcaccacctacccgagcggctgccagctgcgcgccgccagccagagggcc gagagccgcggggagaaggccatcacccaggtcagcaagggcacctgcgagcaaggtcct tccatagtgacgccccccaaggacatctggaatgtcactggtgcccaggtgtacttgagc tgtgaggtcatcggaatcccgacacctgtcctcatctggaacaaggtaaaaaggggtcac tatggagttcaaaggacagaactcctgcctggtgaccgggacaacctggccattcagacc cggggtggcccagaaaagcatgaagtaactggctgggtgctggtatctcctctaagtaag gaagatgctggagaatatgagtgccatgcatccaattcccaaggacaggcttcagcatca gcaaaaattacagtggttgatgccttacatgaaataccagtgaaaaaaggtgaaggtgcc gagctataa |
Protein Sequence |
>3490 : length: 282 MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCC PMCARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVC GSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK EDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL |