Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

3621

Name

ING1

Synonym

p24ING1c|p33|p33ING1|p33ING1b|p47|p47ING1a;inhibitor of growth family, member 1;ING1;inhibitor of growth family, member 1

Definition

growth inhibitor ING1|growth inhibitory protein ING1|inhibitor of growth protein 1|tumor suppressor ING1

Position

13q34

Gene Type

protein-coding

Source

Count: 4; Pubmed_search,TAG,Generif,UniProt

Literature support

Count: 27 PubMed records as below.

Evidence Status

Description

potential

Localization of the candidate tumor suppressor gene ING1 to human chromosome 13q34.

potential

Cellular localization and chromosome mapping of a novel candidate tumor suppressor gene (ING1).

potential

Extension of the replicative life span of human diploid fibroblasts by inhibition of the p33ING1 candidate tumor suppressor.

potential

"A novel candidate tumor suppressor, ING1, is involved in the regulation of apoptosis."

reviewed

The tumor suppressor p33ING1b upregulates p16INK4a expression and induces cellular senescence.

reviewed

Genetic alterations of tumor suppressor ING1 in human non-small cell lung cancer.

reviewed

The tumor suppressor ING1 contributes to epigenetic control of cellular senescence.

reviewed

HECT ubiquitin ligase Smurf1 targets the tumor suppressor ING2 for ubiquitination and degradation.

reviewed

Nuclear exclusion of p33ING1b tumor suppressor protein: explored in HCC cells using a new highly specific antibody.

reviewed

Tethering by laminin A stabilizes and targets the ING1 tumor suppressor.
More detail of all 27 literatures about ING1

External Links

Links to Entrez Gene

3621

Links to all GeneRIF Items

3621

Links to iHOP

3621

Sequence Information

Nucleotide Sequence

>3621 : length: 1269
atgtccttcgtggaatgtccttatcattcccctgcggaacgattggtcgctgaggcggat
gaaggcgggcctagcgcaataactggtatgggtctgtgtttccgctgtcttcttttttct
ttttcggggaggagcggggtggagggtggacgagttgatttgaacgtcttcgggtcgctc
ggcctccagccttggattggttcttctcgctgctggggcgggccgtgctcttccgccctg
cggtgtggttggttctcctcctggcctccgccctccaaatcggcgattcccataggcggc
ggctctcggggtgcggggcgagtctcccgctggcctcctccccattggctggaggcctgg
cgggtgtcgcccctgcccctctccccgctcagcccggccactttcgggcgcggatttata
gcagtagcagtgatcccgggcctgtgggctcggggccggggctgcagttcggaccgcctc
ccgcgacccgcggggccggctcggagacagtttcaggccgcatctctgctgacccgaggg
tggggccgcgcgtggccgtggaaacagatcctgaaggagctagacgagtgctacgagcgc
ttcagtcgcgagacagacggggcgcagaagcggcggatgctgcactgtgtgcagcgcgcg
ctgatccgcagccaggagctgggcgacgagaagatccagatcgtgagccagatggtggag
ctggtggagaaccgcacgcggcaggtggacagccacgtggagctgttcgaggcgcagcag
gagctgggcgacacagcgggcaacagcggcaaggctggcgcggacaggcccaaaggcgag
gcggcagcgcaggctgacaagcccaacagcaagcgctcacggcggcagcgcaacaacgag
aaccgtgagaacgcgtccagcaaccacgaccacgacgacggcgcctcgggcacacccaag
gagaagaaggccaagacctccaagaagaagaagcgctccaaggccaaggcggagcgagag
gcgtcccctgccgacctccccatcgaccccaacgaacccacgtactgtctgtgcaaccag
gtctcctatggggagatgatcggctgcgacaacgacgagtgccccatcgagtggttccac
ttctcgtgcgtggggctcaatcataaacccaagggcaagtggtactgtcccaagtgccgg
ggggagaacgagaagaccatggacaaagccctggagaaatccaaaaaagagagggcttac
aacaggtag

Protein Sequence

>3621 : length: 422
MSFVECPYHSPAERLVAEADEGGPSAITGMGLCFRCLLFSFSGRSGVEGGRVDLNVFGSL
GLQPWIGSSRCWGGPCSSALRCGWFSSWPPPSKSAIPIGGGSRGAGRVSRWPPPHWLEAW
RVSPLPLSPLSPATFGRGFIAVAVIPGLWARGRGCSSDRLPRPAGPARRQFQAASLLTRG
WGRAWPWKQILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVE
LVENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNE
NRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQ
VSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAY
NR



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