Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

3732

Name

CD82

Synonym

4F9|C33|GR15|IA4|KAI1|R2|SAR2|ST6|TSPAN27;CD82 molecule;CD82;CD82 molecule

Definition

C33 antigen|CD82 antigen|inducible membrane protein R2|kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))|metastasis suppressor Kangai-1|tetraspanin-27|tspan-27

Position

11p11.2

Gene Type

protein-coding

Source

Count: 3; Pubmed_search,TAG,Generif

Literature support

Count: 2 PubMed records as below.

Evidence Status

Description

reviewed

"tumor suppressor KAI1 affects integrin alphavbeta3-mediated ovarian cancer cell adhesion, motility, and proliferation."

reviewed

KAI1 is a tumor metastasis suppressor gene in digestive tract carcinomas and cancer cells.
More detail of all 2 literatures about CD82

Pathways and Diseases

Pathway

p53 pathway;PANTHER;P00059

Pathway

Direct p53 effectors;PID Curated;200101

Pathway

p53 signaling pathway;KEGG PATHWAY;hsa04115

Disease

Cancer;FunDO

Disease

Prostate cancer, susceptibility to;OMIM

Disease

Penile disease;FunDO

External Links

Links to Entrez Gene

3732

Links to all GeneRIF Items

3732

Links to iHOP

3732

Sequence Information

Nucleotide Sequence

>3732 : length: 729
atgggctcagcctgtatcaaagtcaccaaatactttctcttcctcttcaacttgatcttc
tttatcctgggcgcagtgatcctgggcttcggggtgtggatcctggccgacaagagcagt
ttcatctctgtcctgcaaacctcctccagctcgcttaggatgggggcctatgtcttcatc
ggcgtgggggcagtcactatgctcatgggcttcctgggctgcatcggcgccgtcaacgag
gtccgctgcctgctggggctgctgaagcaggagatgggcggcatcgtgactgagctcatt
cgagactacaacagcagtcgcgaggacagcctgcaggatgcctgggactacgtgcaggct
caggtgaagtgctgcggctgggtcagcttctacaactggacagacaacgctgagctcatg
aatcgccctgaggtcacctacccctgttcctgcgaagtcaagggggaagaggacaacagc
ctttctgtgaggaagggcttctgcgaggcccccggcaacaggacccagagtggcaaccac
cctgaggactggcctgtgtaccaggagggctgcatggagaaggtgcaggcgtggctgcag
gagaacctgggcatcatcctcggcgtgggcgtgggtgtggccatcatcgagctcctgggg
atggtcctgtccatctgcttgtgccggcacgtccattccgaagactacagcaaggtcccc
aagtactga

Protein Sequence

>3732 : length: 242
MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI
GVGAVTMLMGFLGCIGAVNEVRCLLGLLKQEMGGIVTELIRDYNSSREDSLQDAWDYVQA
QVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNSLSVRKGFCEAPGNRTQSGNH
PEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRHVHSEDYSKVP
KY



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