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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 4013 |
Name | VWA5A |
Synonym | BCSC-1|BCSC1|LOH11CR2A;von Willebrand factor A domain containing 5A;VWA5A;von Willebrand factor A domain containing 5A |
Definition | breast cancer suppressor candidate 1|loss of heterozygosity 11 chromosomal region 2 gene A protein|loss of heterozygosity, 11, chromosomal region 2, gene A|ortholog of mouse AW551984|von Willebrand factor A domain-containing protein 5A |
Position | 11q24.1 |
Gene Type | protein-coding |
Source | Count: 4; Pubmed_search,TAG,UniProt,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
potential | The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene. |
reviewed | tumor suppressor function of BCSC-1 in nasopharyngeal carcinoma. |
reviewed | increased E-cadherin and alpha-catenin expression and reduced Wnt signaling might be involved in the mechanisms of tumor suppressor function of BCSC-1. |
| More detail of all 2 literatures about VWA5A | |
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External Links |
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Links to Entrez Gene | 4013 |
Links to all GeneRIF Items | 4013 |
Links to iHOP | 4013 |
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Sequence Information |
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Nucleotide Sequence |
>4013 : length: 2361 atggtgcacttctgtggcctactcaccctccaccgggagccagtgccgctgaagagtatc tctgtgagcgtgaacatttacgagtttgtggctggtgtgtctgcaactttgaactacgag aatgaggagaaagttcctttggaggccttctttgtgttccccatggatgaagactctgct gtttacagctttgaggccttggtggatgggaagaaaattgtagcagaattacaagacaag atgaaggcccgcaccaactatgagaaagccatctcccagggccaccaggccttcttattg gagggggacagcagctccagggatgtcttctcttgcaatgtgggtaacctccaacctggg tcgaaggcggcagtcaccctgaagtatgtgcaggagctgcctctggaagcagatggggct ctgcgctttgtgctcccagctgtcctgaatcctagataccagttctctgggtcgtctaag gacagttgccttaatgtgaagactcctatagtccctgtggaggacctgccctacacactc agcatggtcgccaccatagattcccagcatggcattgagaaggtccaatccaactgcccc ttgagtcctaccgagtacctaggagaggacaagacttctgctcaggtttccctggctgct ggacacaagtttgatcgggacgtggaactcctgatttactacaatgaggtgcataccccc agcgtggttttggagatggggatgcctaacatgaagccaggtcatttgatgggagatcca tctgcaatggtgagtttctatccaaatatcccagaagatcaaccatcaaatacctgtgga gagtttatctttctcatggaccgctcgggaagtatgcagagccccatgagtagccaggat acatctcagctgcgaatacaggcagccaaggaaacactgattttgctgctgaagagttta cctataggctgttatttcaacatctatggatttggctcttcctatgaggcatgctttccg gagagtgtgaagtacactcagcaaacaatggaggaggctctggggagagtgaagcttatg caggccgacctagggggcactgaaatcttggcaccactccagaacatttacaggggaccc tccatcccaggccaccccctacagctttttgtctttacagatggagaagttacagacacg tttagtgtaattaaagaagttaggatcaacagacagaaacacaggtgtttctcatttggt attggagaaggcacctccaccagcctaataaaaggtattgcccgggcatcagggggcacc tcagaatttatcacaggcaaagacaggatgcagtccaaggctctcaggactctgaaacgc tctctgcagcctgtggtagaggatgtctctctgagctggcatttgcctcctggtctgtct gctaaaatgctttccccagaacagactgtcatctttaggggtcagagattaatcagctat gcccagctgaccgggaggatgccagcagcagagacaacaggagaagtatgcctcaaatat acactccagggcaagacttttgaggataaggtgacatttcctctacaacccaagcctgat gtcaacctcaccattcaccgccttgctgccaagtccttgctccagaccaaggacatgggc ctcagggagactccagcaagtgataaaaaagatgcattgaaccttagccttgagtctggt gtcataagctccttcacagctttcattgctatcaataaggagctcaacaagccggttcag gggcctctggctcatagggacgtcccaaggccaattctgttgggtgcttctgccccattg aagataaaatgccaatcaggttttcgaaaggccttacactctgaccgtcctccttctgca tctcagcccagaggggaacttatgtgttataaggccaagacattccagatggacgattac agtctctgtgggttgataagtcacaaggaccagcacagtccaggctttggagagaatcac cttgtgcagctgatttaccaccaaaatgcaaatggttcctgggatctgaatgaagatcta gccaagatcctaggtatgagtttggaagaaataatggctgcacagcctgccgagcttgtg gattcctcaggctgggccaccatcctggccgtgatctggctgcacagcaatggtaaggac ttgaagtgtgaatgggagcttctggaaaggaaggccgtggcctggatgcgtgcccatgca ggctccaccatgccttcggttgtgaaagctgctattactttcctgaagtcatctgtggat cctgctatctttgccttttga |
Protein Sequence |
>4013 : length: 786 MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSA VYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPG SKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTL SMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTP SVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQD TSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLM QADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFG IGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLS AKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPD VNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQ GPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSASQPRGELMCYKAKTFQMDDY SLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELV DSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAGSTMPSVVKAAITFLKSSVD PAIFAF |