Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

407042

Name

MIR34C

Synonym

MIRN34C|miRNA34C;microRNA 34c;MIR34C;microRNA 34c

Definition

-

Position

11q23.1

Gene Type

miscRNA

Source

Count: 1; Generif

Literature support

Count: 3 PubMed records as below.

Evidence Status

Description

reviewed

These results suggest differential tumor suppressor roles for miR-34c-3p and miR-34c-5p and provide new insights in the understanding of miRNA biology.

potential

"This study, we performed a comprehensive analysis of putative human miRNA oncogenes and tumor suppressors. We found that miRNA oncogenes and tumor suppressors clearly show different patterns in function, evolutionary rate, expression, chromosome distribution, molecule size, free energy, transcription factors, and targets."

reviewed

"miR-34b/c and BTG4 are novel tumor suppressors in colorectal cancer (CRC) and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC".
More detail of all 3 literatures about MIR34C

External Links

Links to Entrez Gene

407042

Links to all GeneRIF Items

407042

Links to iHOP

407042

Sequence Information

Nucleotide Sequence

>407042 : length: 23
aggcagtgtagttagctgattgc



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