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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 4485 |
Name | MST1 |
Synonym | D3F15S2|DNF15S2|HGFL|MSP|NF15S2;macrophage stimulating 1 (hepatocyte growth factor-like);MST1;macrophage stimulating 1 (hepatocyte growth factor-like) |
Definition | hepatocyte growth factor-like protein|hepatocyte growth factor-like protein homolog|macrophage stimulatory protein|macrophage-stimulating protein |
Position | 3p21 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
reviewed | "the oncogenic effect of BRAF(V600E) is associated with the inhibition of MST1 tumor suppressor pathways, and that the activity of RASSF1A-MST1-FoxO3 pathways determines the phenotypes of BRAF(V600E) tumors." |
| More detail of all 1 literatures about MST1 | |
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Pathways and Diseases |
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Pathway | a6b1 and a6b4 Integrin signaling;PID Curated;200162 |
Pathway | FoxO family signaling;PID Curated;200091 |
Disease | IMMUNE;GAD |
Disease | Crohn's disease;GAD |
Disease | Ulcerative colitis;NHGRI |
Disease | Crohn's disease;NHGRI |
Disease | Endometriosis;FunDO |
Disease | ulcerative colitis;GAD |
Disease | Breast cancer;FunDO |
Disease | Neoplasm metastasis;FunDO |
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External Links |
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Links to Entrez Gene | 4485 |
Links to all GeneRIF Items | 4485 |
Links to iHOP | 4485 |
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Sequence Information |
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Nucleotide Sequence |
>4485 : length: 2178 atggggctgtggtgggtcacagtgcagcctccagccagaaggatggggtggctcccactc ctgctgcttctgactcaatgcttaggggtccctgggcagcgctcgccattgaatgacttc caagtgctccggggcacagagctacagcacctgctacatgcggtggtgcccgggccttgg caggaggatgtggcagatgctgaagagtgtgctggtcgctgtgggcccttaatggactgc cgggccttccactacaacgtgagcagccatggttgccaactgctgccatggactcaacac tcgccccacacgaggctgcggcgttctgggcgctgtgacctcttccagaagaaagactac gtacggacctgcatcatgaacaatggggttgggtaccggggcaccatggccacgaccgtg ggtggcctgccctgccaggcttggagccacaagttcccaaatgatcacaagtacacgccc actctccggaatggcctggaagagaacttctgccgtaaccctgatggcgaccccggaggt ccttggtgctacacaacagaccctgctgtgcgcttccagagctgcggcatcaaatcctgc cgggaggccgcgtgtgtctggtgcaatggcgaggaataccgcggcgcggtagaccgcacg gagtcagggcgcgagtgccagcgctgggatcttcagcacccgcaccagcaccccttcgag ccgggcaagttcctcgaccaaggtctggacgacaactattgccggaatcctgacggctcc gagcggccatggtgctacactacggatccgcagatcgagcgagagttctgtgacctcccc cgctgcgggtccgaggcacagccccgccaagaggccacaactgtcagctgcttccgcggg aagggtgagggctaccggggcacagccaataccaccactgcgggcgtaccttgccagcgt tgggacgcgcaaatcccgcatcagcaccgatttacgccagaaaaatacgcgtgcaaagac cttcgggagaacttctgccggaaccccgacggctcagaggcgccctggtgcttcacactg cggcccggcatgcgcgcggccttttgctaccagatccggcgttgtacagacgacgtgcgg ccccaggactgctaccacggcgcaggggagcagtaccgcggcacggtcagcaagacccgc aagggtgtccagtgccagcgctggtccgctgagacgccgcacaagccgcagttcacgttt acctccgaaccgcatgcacaactggaggagaacttctgccggaacccagatggggatagc catgggccctggtgctacacgatggacccaaggaccccattcgactactgtgccctgcga cgctgcgctgatgaccagccgccatcaatcctggaccccccagaccaggtgcagtttgag aagtgtggcaagagggtggatcggctggatcagcggcgttccaagctgcgcgtggttggg ggccatccgggcaactcaccctggacagtcagcttgcggaatcggcagggccagcatttc tgcggggggtctctagtgaaggagcagtggatactgactgcccggcagtgcttctcctcc tgccatatgcctctcacgggctatgaggtatggttgggcaccctgttccagaacccacag catggagagccaagcctacagcgggtcccagtagccaagatggtgtgtgggccctcaggc tcccagcttgtcctgctcaagctggagagatctgtgaccctgaaccagcgtgtggccctg atctgcctgccccctgaatggtatgtggtgcctccagggaccaagtgtgagattgcaggc tggggtgagaccaaaggtacgggtaatgacacagtcctaaatgtggccttgctgaatgtc atctccaaccaggagtgtaacatcaagcaccgaggacgtgtgcgggagagtgagatgtgc actgagggactgttggcccctgtgggggcctgtgagggtgactacgggggcccacttgcc tgctttacccacaactgctgggtcctggaaggaattataatccccaaccgagtatgcgca aggtcccgctggccagctgtcttcacgcgtgtctctgtgtttgtggactggattcacaag gtcatgagactgggttag |
Protein Sequence |
>4485 : length: 725 MGLWWVTVQPPARRMGWLPLLLLLTQCLGVPGQRSPLNDFQVLRGTELQHLLHAVVPGPW QEDVADAEECAGRCGPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLFQKKDY VRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLRNGLEENFCRNPDGDPGG PWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFE PGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVSCFRG KGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFTL RPGMRAAFCYQIRRCTDDVRPQDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTF TSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRCADDQPPSILDPPDQVQFE KCGKRVDRLDQRRSKLRVVGGHPGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSS CHMPLTGYEVWLGTLFQNPQHGEPSLQRVPVAKMVCGPSGSQLVLLKLERSVTLNQRVAL ICLPPEWYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKHRGRVRESEMC TEGLLAPVGACEGDYGGPLACFTHNCWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHK VMRLG |