Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

4601

Name

MXI1

Synonym

MAD2|MXD2|MXI|bHLHc11;MAX interactor 1;MXI1;MAX interactor 1

Definition

MAX dimerization protein 2|Max-related transcription factor|class C basic helix-loop-helix protein 11|max-interacting protein 1

Position

10q24-q25

Gene Type

protein-coding

Source

Count: 3; Pubmed_search,TAG,Generif

Literature support

Count: 4 PubMed records as below.

Evidence Status

Description

potential

"Genomic organization of human MXI1, a putative tumor suppressor gene."

reviewed

Identification and analysis of tumor suppressor loci at chromosome 10q23.3-10q25.3 in medulloblastoma.

potential

Data show that PTEN and MXI1 were two candidate tumor suppressor genes on 10q23 and 10q24-q25 and may be potentially involved in the initiation and progression of prostate carcinoma.

potential

These findings support MXI1 as a putative tumor suppressor gene involved in conventional melanoma progression.
More detail of all 4 literatures about MXI1

External Links

Links to Entrez Gene

4601

Links to all GeneRIF Items

4601

Links to iHOP

4601

Sequence Information

Nucleotide Sequence

>4601 : length: 549
atgccgagcccccgactgcagcattcaaagcccccacggaggttgagccgggcacagaaa
cacagcagcgggagcagcaacaccagcactgccaacagacgagctcatctgcgcctttgt
ttagaacgcttaaaagttctgattccactaggaccagactgcacccggcacacaacactt
ggtttgctcaacaaagccaaagcacacatcaagaaacttgaagaagctgaaagaaaaagc
cagcaccagctcgagaatttggaacgagaacagagatttttaaagtggcgactggaacag
ctgcagggtcctcaggagatggaacgaatacgaatggacagcattggatcaactatttct
tcagatcgttctgattcagagcgagaggagattgaagtggatgttgaaagcacagagttc
tcccatggagaagtggacaatataagtaccaccagcatcagtgacattgatgaccacagc
agcctgccgagtattgggagtgacgagggttactccagtgccagtgtcaaactttcattc
acttcatag

Protein Sequence

>4601 : length: 182
MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRRAHLRLCLERLKVLIPLGPDCTRHTTL
GLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTIS
SDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSF
TS



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