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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5079 |
Name | PAX5 |
Synonym | BSAP;paired box 5;PAX5;paired box 5 |
Definition | B cell specific activator protein|B-cell lineage specific activator|B-cell-specific transcription factor|paired box homeotic gene 5|paired box protein Pax-5|transcription factor PAX 5 |
Position | 9p13 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
reviewed | tumor suppressor gene PAX5 is inactivated by promoter methylation in liver cancer. PAX5 contributes to suppression of hepatocarcinogenesis by inhibiting cell proliferation and inducing cell apoptosis through direct regulating p53 signaling pathway. |
| More detail of all 1 literatures about PAX5 | |
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Pathways and Diseases |
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Pathway | C-MYB transcription factor network;PID Curated;200130 |
Disease | Cancers;KEGG DISEASE |
Disease | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma;GAD |
Disease | Cancers of haematopoietic and lymphoid tissues;KEGG DISEASE |
Disease | Lymphoplasmacytic lymphoma;KEGG DISEASE;H00011 |
Disease | CANCER;GAD |
Disease | Cancer;FunDO |
Disease | Lymphoplasmacytoid lymphoma;OMIM |
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External Links |
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Links to Entrez Gene | 5079 |
Links to all GeneRIF Items | 5079 |
Links to iHOP | 5079 |
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Sequence Information |
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Nucleotide Sequence |
>5079 : length: 1176 atggatttagagaaaaattatccgactcctcggaccagcaggacaggacatggaggagtg aatcagcttgggggggtttttgtgaatggacggccactcccggatgtagtccgccagagg atagtggaacttgctcatcaaggtgtcaggccctgcgacatctccaggcagcttcgggtc agccatggttgtgtcagcaaaattcttggcaggtattatgagacaggaagcatcaagcct ggggtaattggaggatccaaaccaaaggtcgccacacccaaagtggtggaaaaaatcgct gaatataaacgccaaaatcccaccatgtttgcctgggagatcagggaccggctgctggca gagcgggtgtgtgacaatgacaccgtgcctagcgtcagttccatcaacaggatcatccgg acaaaagtacagcagccacccaaccaaccagtcccagcttccagtcacagcatagtgtcc actggctccgtgacgcaggtgtcctcggtgagcacggattcggccggctcgtcgtactcc atcagcggcatcctgggcatcacgtcccccagcgccgacaccaacaagcgcaagagagac gaaggtattcaggagtctccggtgccgaacggccactcgcttccgggcagagacttcctc cggaagcagatgcggggagacttgttcacacagcagcagctggaggtgctggaccgcgtg tttgagaggcagcactactcagacatcttcaccaccacagagcccatcaagcccgagcag accacagagtattcagccatggcctcgctggctggtgggctggacgacatgaaggccaat ctggccagccccacccctgctgacatcgggagcagtgtgccaggcccgcagtcctacccc attgtgacaggccgtgacttggcgagcacgaccctccccgggtaccctccacacgtcccc cccgctggacagggcagctactcagcaccgacgctgacagggatggtgcctgggagtgag ttttccgggagtccctacagccaccctcagtattcctcgtacaacgactcctggaggttc cccaacccggggctgcttggctccccctactattatagcgctgccgcccgaggagccgcc ccacctgcagccgccactgcctatgaccgtcactga |
Protein Sequence |
>5079 : length: 391 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYP IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF PNPGLLGSPYYYSAAARGAAPPAAATAYDRH |