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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5157 |
Name | PDGFRL |
Synonym | PDGRL|PRLTS;platelet-derived growth factor receptor-like;PDGFRL;platelet-derived growth factor receptor-like |
Definition | PDGF receptor beta-like tumor suppressor|PDGFR-like protein|platelet-derived growth factor receptor-like protein|platelet-derived growth factor-beta-like tumor suppressor |
Position | 8p22-p21.3 |
Gene Type | protein-coding |
Source | Count: 3; Pubmed_search,TAG,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
potential | Isolation of a candidate tumor suppressor gene on chromosome 8p21.3-p22 that is homologous to an extracellular domain of the PDGF receptor beta gene. |
potential | "Results indicate that PDGFRL functions as a tumor suppressor, inhibiting the growth of colorectal cancer cells." |
| More detail of all 2 literatures about PDGFRL | |
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Pathways and Diseases |
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Pathway | PDGF signaling pathway;PANTHER;P00047 |
Disease | Colorectal cancer;OMIM |
Disease | Hepatocellular cancer;OMIM |
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External Links |
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Links to Entrez Gene | 5157 |
Links to all GeneRIF Items | 5157 |
Links to iHOP | 5157 |
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Sequence Information |
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Nucleotide Sequence |
>5157 : length: 1128 atgaaggtctggctgctgcttggtcttctgctggtgcacgaagcgctggaggatgttact ggccaacaccttcccaagaacaagcgtccaaaagaaccaggagagaatagaatcaaacct accaacaagaaggtgaagcccaaaattcctaaaatgaaggacagggactcagccaattca gcaccaaagacgcagtctatcatgatgcaagtgctggataaaggtcgcttccagaaaccc gccgctaccctgagtctgctggcggggcaaactgtagagcttcgatgtaaagggagtaga attgggtggagctaccctgcgtatctggacacctttaaggattctcgcctcagcgtcaag cagaatgagcgctacggccagttgactctggtcaactccacctcggcagacacaggtgaa ttcagctgctgggtgcagctctgcagcggctacatctgcaggaaggacgaggccaaaacg ggctccacctacatcttttttacagagaaaggagaactctttgtaccttctcccagctac ttcgatgttgtctacttgaacccggacagacaggctgtggttccttgtcgggtgaccgtg ctgtcggccaaagtcacgctccacagggaattcccagccaaggagatcccagccaatgga acggacattgtttatgacatgaagcggggctttgtgtatctgcaacctcattccgagcac cagggtgtggtttactgcagggcggaggccgggggcagatctcagatctccgtcaagtac cagctgctctacgtggcggttcccagtggccctccctcaacaaccatcttggcttcttca aacaaagtgaaaagtggggacgacatcagtgtgctctgcactgtcctgggggagcccgat gtggaggtggagttcacctggatcttcccagggcagaaggatgaaaggcctgtgacgatc caagacacttggaggttgatccacagaggactgggacacaccacgagaatctcccagagt gtcattacagtggaagactttgagacgattgatgcaggatattacatttgcactgctcag aatcttcaaggacagaccacagtagctaccactgttgagttttcctga |
Protein Sequence |
>5157 : length: 375 MKVWLLLGLLLVHEALEDVTGQHLPKNKRPKEPGENRIKPTNKKVKPKIPKMKDRDSANS APKTQSIMMQVLDKGRFQKPAATLSLLAGQTVELRCKGSRIGWSYPAYLDTFKDSRLSVK QNERYGQLTLVNSTSADTGEFSCWVQLCSGYICRKDEAKTGSTYIFFTEKGELFVPSPSY FDVVYLNPDRQAVVPCRVTVLSAKVTLHREFPAKEIPANGTDIVYDMKRGFVYLQPHSEH QGVVYCRAEAGGRSQISVKYQLLYVAVPSGPPSTTILASSNKVKSGDDISVLCTVLGEPD VEVEFTWIFPGQKDERPVTIQDTWRLIHRGLGHTTRISQSVITVEDFETIDAGYYICTAQ NLQGQTTVATTVEFS |