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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5178 |
Name | PEG3 |
Synonym | PW1|ZNF904|ZSCAN24;paternally expressed 3;PEG3;paternally expressed 3 |
Definition | Kruppel-type zinc finger protein|paternally-expressed gene 3 protein|zinc finger and SCAN domain-containing protein 24 |
Position | 19q13.4 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
reviewed | Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation. |
reviewed | "Loss of PEG3 expression may be a frequent event in gynecologic cancers. Given the known role of PEG3 in p53-mediated apoptosis, it is possible that PEG3 functions as a tumor suppressor." |
| More detail of all 2 literatures about PEG3 | |
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External Links |
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Links to Entrez Gene | 5178 |
Links to all GeneRIF Items | 5178 |
Links to iHOP | 5178 |
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Sequence Information |
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Nucleotide Sequence |
>5178 : length: 4767 atgctgcctccaaagcacttgtctgccaccaaacctaagaagtcctgggccccaaatctg tatgagctagacagtgacttgactaaggagccggatgtcatcataggagaaggtccaact gactctgagttttttcatcagaggtttcggaacctaatctatgtggaatttgttgggcct cggaagaccctgatcaaactccgaaacctctgcctcgattggttgcagccggagacccgc accaaggaggagatcatcgagctcttggtccttgagcagtacctgaccatcatccctgaa aagctcaagccttgggtgcgagcaaaaaagccggagaactgtgagaagctcgtcactctg ctggagaattacaaggagatgtaccaaccagaagacgacaacaacagtgacgtgaccagc gacgacgacatgacccggaacagaagagagtcctcaccacctcactcagtccattctttc agtgaccgggactgggaccggaggggcagaagcagagacatggagccacgagaccgctgg tcccacaccaggaacccaagaagcaggatgcctccgcgggatctttcccttcctgtggtg gcgaaaacaagctttgaaatggacagagaggacgacagggactccagggcttatgagtcc cgatctcaggatgctgaatcataccaaaatgtggtggacctcgctgaggacaggaaacct cacaacacaatccaggacaacatggaaaactacaggaagctgctctccctcgtgcagctt gctgaagacgatggccactcccacatgacgcagggccactcatcaagatccaagagaagt gcctacccaagcaccagtcgaggtctaaaaactatgcctgaagccaaaaaatcaacccac cggcgggggatttgtgaagatgaatcttcccacggagtgataatggaaaaattcatcaag gatgtgtcacgcagttccaaatcgggaagagcaagggagtcaagcgaccggtcacagaga ttccccagaatgtcagatgataactggaaggacatttcattgaacaagagggagtcagtg atccagcagcgggtttatgaagggaatgcatttaggggaggctttaggtttaattcaacc cttgtttccagaaagagagttcttgaaagaaagaggcgctatcattttgacacagatggg aagggctcgattcacgatcaaaaaggctgtcccaggaagaagccctttgaatgtggtagt gagatgagaaaagccatgagcgtgagcagcctgagcagcctcagctccccctcctttacc gagtcacagccaattgattttggggcaatgccatatgtatgtgatgagtgtgggaggtcg ttcagtgtcatctcagaatttgttgagcaccagatcatgcatactagagagaacctctat gagtatggtgagtcctttatccacagtgtggctgtcagtgaagttcagaaaagtcaggtt ggagggaaacgttttgaatgtaaggactgtggagagaccttcaataagagtgccgccttg gctgaacatcggaagattcatgctagaggttatcttgtggaatgtaagaatcaggaatgt gaggaagccttcatgcctagccccacctttagtgagcttcagaaaatatatggcaaagac aaattctacgagtgcagggtgtgtaaggaaaccttccttcatagttctgccctgattgag caccagaaaatccactttggggatgacaaagataatgagcgtgaacatgaacgtgaacgt gaacgtgagcgcggggaaacctttaggcccagcccagcccttaatgagtttcagaaaatg tatggtaaagagaaaatgtacgaatgtaaggtgtgtggggagactttccttcatagctca tccctgaaagaacatcagaaaatccatactagagggaacccatttgaaaacaagggtaaa gtgtgtgaggaaacctttattcctggtcagtcccttaaaaggcgtcagaaaacttacaat aaggagaagctctgtgactttacagatggccgggatgccttcatgcaaagctcagagctc agtgagcatcagaaaattcattctcgaaagaacctctttgaaggcagagggtatgagaaa tctgtcattcatagtgggccattcactgaatctcagaagagtcatactataacaagacct cttgaaagtgatgaggacgaaaaggcgttcaccattagctctaacccctatgaaaaccag aagattcccactaaggaaaatgtctatgaggcaaaatcatatgagaggtctgttattcat agcttagcctctgtggaagctcagaaaagtcacagtgtagcagggcccagtaaaccaaaa gtaatggcagagtctaccattcagagcttcgatgctatcaaccatcagagagttcgtgct ggagggaacacctctgaaggaagggaatacagtaggtctgttatccatagcttagtggct tccaaacctccaagaagtcacaatggaaatgaattggtggaatctaatgagaagggagaa tcctccatttatatctcagaccttaatgataagcgacagaagattcctgccagagagaac ccttgtgaagggggcagtaagaatcgcaactatgaagactctgtcatacagagtgtattc cgtgccaaacctcagaaaagtgttcctggagagggatctggtgagtttaagaaggatggc gaattctctgttcccagctcaaatgtccgtgaataccagaaggctcgtgctaaaaagaaa tacattgagcataggagcaatgagacctctgtaattcactctctgccttttggtgaacaa acatttcgccctcgagggatgctctatgaatgtcaggagtgtggggagtgctttgctcat agctctgacctcactgagcaccagaagattcatgatagggagaagccctctggaagcaga aactatgaatggtctgtcattcgcagcttggcccctactgaccctcaaacaagttacgcc caagagcagtatgctaaagagcaagcgcggaacaaatgtaaggacttcagacaatttttt gctaccagcgaagacctcaacacaaaccagaaaatctatgaccaagagaagtctcatggc gaggagtctcaaggcgagaatactgatggggaggagacccacagcgaggagacccatggt caggagacaattgaagaccctgtcattcaaggctcagacatggaagaccctcagaaggat gaccctgatgacaaaatctatgaatgtgaggactgtggcctgggctttgtggatctcaca gacctcacagaccatcagaaagtccacagcaggaagtgcctggttgacagtcgggagtac acacattctgtaattcacacccattccatcagcgagtatcagagagattacactggagag cagctgtatgaatgtccaaagtgtggggaatcttttattcatagctcattccttttcgag catcagagaatccatgaacaagaccagttgtattccatgaaggggtgtgatgatggtttt attgccctcttgcccatgaagccacggaggaatcgtgctgcagagaggaatcctgctctt gctgggtcggccattcgatgccttttgtgtggacaaggcttcattcatagctctgccctt aatgagcatatgagacttcatagggaagatgatttactggagcagagccagatggctgag gaagctatcattccaggcttagccctcactgagtttcagagaagtcagaccgaagagaga ctctttgaatgtgcagtctgtggagaatctttcgtcaacccagcagaacttgcagatcac gtaactgttcataagaatgagccctatgagtacgggtcctcctatactcacacctcattt cttactgagcccctcaaaggagctataccattctatgaatgcaaggattgtggtaagtcc tttattcatagcacagtcctcactaaacataaggagcttcatctggaagaagaagaagaa gatgaagcagcagcagctgcagcagcagcagcccaggaagttgaagccaatgtccatgtt ccacaagtagttctgaggattcagggcttaaacgtagaggctgctgagccagaagtggag gctgccgagccagaagtggaggctgctgagccagaagtggaggctgctgagccaaacgga gaggctgaagggccagatggagaggctgcagagcccattggagaggctggacagccaaat ggagaggccgagcagccaaatggggatgctgatgagccagatggtgcaggtattgaagac ccagaagaaagagctgaagagccagagggaaaagctgaagagccagagggagatgccgac gagcctgacggtgtgggaattgaagacccagaagaaggtgaagatcaagagattcaggta gaagaaccatactatgactgccatgaatgcacagaaaccttcacttccagcacagcattc agtgaacacctgaaaactcatgccagcatgatcatatttgagcctgcaaatgcctttggg gagtgctcaggctacatcgaacgtgccagcaccagcacaggtggtgccaatcaagctgat gagaagtacttcaaatgtgacgtctgtgggcagctcttcaatgaccgcctgtccctcgcc agacaccagaatacccacactggctga |
Protein Sequence |
>5178 : length: 1588 MLPPKHLSATKPKKSWAPNLYELDSDLTKEPDVIIGEGPTDSEFFHQRFRNLIYVEFVGP RKTLIKLRNLCLDWLQPETRTKEEIIELLVLEQYLTIIPEKLKPWVRAKKPENCEKLVTL LENYKEMYQPEDDNNSDVTSDDDMTRNRRESSPPHSVHSFSDRDWDRRGRSRDMEPRDRW SHTRNPRSRMPPRDLSLPVVAKTSFEMDREDDRDSRAYESRSQDAESYQNVVDLAEDRKP HNTIQDNMENYRKLLSLVQLAEDDGHSHMTQGHSSRSKRSAYPSTSRGLKTMPEAKKSTH RRGICEDESSHGVIMEKFIKDVSRSSKSGRARESSDRSQRFPRMSDDNWKDISLNKRESV IQQRVYEGNAFRGGFRFNSTLVSRKRVLERKRRYHFDTDGKGSIHDQKGCPRKKPFECGS EMRKAMSVSSLSSLSSPSFTESQPIDFGAMPYVCDECGRSFSVISEFVEHQIMHTRENLY EYGESFIHSVAVSEVQKSQVGGKRFECKDCGETFNKSAALAEHRKIHARGYLVECKNQEC EEAFMPSPTFSELQKIYGKDKFYECRVCKETFLHSSALIEHQKIHFGDDKDNEREHERER ERERGETFRPSPALNEFQKMYGKEKMYECKVCGETFLHSSSLKEHQKIHTRGNPFENKGK VCEETFIPGQSLKRRQKTYNKEKLCDFTDGRDAFMQSSELSEHQKIHSRKNLFEGRGYEK SVIHSGPFTESQKSHTITRPLESDEDEKAFTISSNPYENQKIPTKENVYEAKSYERSVIH SLASVEAQKSHSVAGPSKPKVMAESTIQSFDAINHQRVRAGGNTSEGREYSRSVIHSLVA SKPPRSHNGNELVESNEKGESSIYISDLNDKRQKIPARENPCEGGSKNRNYEDSVIQSVF RAKPQKSVPGEGSGEFKKDGEFSVPSSNVREYQKARAKKKYIEHRSNETSVIHSLPFGEQ TFRPRGMLYECQECGECFAHSSDLTEHQKIHDREKPSGSRNYEWSVIRSLAPTDPQTSYA QEQYAKEQARNKCKDFRQFFATSEDLNTNQKIYDQEKSHGEESQGENTDGEETHSEETHG QETIEDPVIQGSDMEDPQKDDPDDKIYECEDCGLGFVDLTDLTDHQKVHSRKCLVDSREY THSVIHTHSISEYQRDYTGEQLYECPKCGESFIHSSFLFEHQRIHEQDQLYSMKGCDDGF IALLPMKPRRNRAAERNPALAGSAIRCLLCGQGFIHSSALNEHMRLHREDDLLEQSQMAE EAIIPGLALTEFQRSQTEERLFECAVCGESFVNPAELADHVTVHKNEPYEYGSSYTHTSF LTEPLKGAIPFYECKDCGKSFIHSTVLTKHKELHLEEEEEDEAAAAAAAAAQEVEANVHV PQVVLRIQGLNVEAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEAAEPIGEAGQPN GEAEQPNGDADEPDGAGIEDPEERAEEPEGKAEEPEGDADEPDGVGIEDPEEGEDQEIQV EEPYYDCHECTETFTSSTAFSEHLKTHASMIIFEPANAFGECSGYIERASTSTGGANQAD EKYFKCDVCGQLFNDRLSLARHQNTHTG |