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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 5245 |
Name | PHB |
Synonym | PHB1;prohibitin;PHB;prohibitin |
Definition | - |
Position | 17q21 |
Gene Type | protein-coding |
Source | Count: 3; Pubmed_search,TAG,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
potential | "PHB is reported to have tumour suppressor, anti-proliferative and cell cycle regulation activities, largely accomplished through its repression of E2F activity." |
potential | "Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function." |
| More detail of all 2 literatures about PHB | |
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External Links |
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Links to Entrez Gene | 5245 |
Links to all GeneRIF Items | 5245 |
Links to iHOP | 5245 |
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Sequence Information |
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Nucleotide Sequence |
>5245 : length: 819 atggctgccaaagtgtttgagtccattggcaagtttggcctggccttagctgttgcagga ggcgtggtgaactctgccttatataatgtggatgctgggcacagagctgtcatctttgac cgattccgtggagtgcaggacattgtggtaggggaagggactcattttctcatcccgtgg gtacagaaaccaattatctttgactgccgttctcgaccacgtaatgtgccagtcatcact ggtagcaaagatttacagaatgtcaacatcacactgcgcatcctcttccggcctgtcgcc agccagcttcctcgcatcttcaccagcatcggagaggactatgatgagcgtgtgctgccg tccatcacaactgagatcctcaagtcagtggtggctcgctttgatgctggagaactaatc acccagagagagctggtctccaggcaggtgagcgacgaccttacagagcgagccgccacc tttgggctcatcctggatgacgtgtccttgacacatctgaccttcgggaaggagttcaca gaagcggtggaagccaaacaggtggctcagcaggaagcagagagggccagatttgtggtg gaaaaggctgagcaacagaaaaaggcggccatcatctctgctgagggcgactccaaggca gctgagctgattgccaactcactggccactgcaggggatggcctgatcgagctgcgcaag ctggaagctgcagaggacatcgcgtaccagctctcacgctctcggaacatcacctacctg ccagcggggcagtccgtgctcctccagctgccccagtga |
Protein Sequence |
>5245 : length: 272 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ |