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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5320 |
Name | PLA2G2A |
Synonym | MOM1|PLA2|PLA2B|PLA2L|PLA2S|PLAS1|sPLA2;phospholipase A2, group IIA (platelets, synovial fluid);PLA2G2A;phospholipase A2, group IIA (platelets, synovial fluid) |
Definition | GIIC sPLA2|NPS-PLA2|group IIA phospholipase A2|non-pancreatic secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 2A|phospholipase A2, membrane associated |
Position | 1p35 |
Gene Type | protein-coding |
Source | Count: 2; TAG,Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | "Here, we report that a cosmid transgene overexpressing Pla2g2a caused a reduction in tumour multiplicity and size, comparable to that conferred by a single copy of the resistance allele of Mom1. These results offer strong evidence that this secretory phospholipase can provide active tumour resistance. ". |
| More detail of all 1 literatures about PLA2G2A | |
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Pathways and Diseases |
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Pathway | Vascular smooth muscle contraction;KEGG PATHWAY;hsa04270 |
Pathway | VEGF signaling pathway;KEGG PATHWAY;hsa04370 |
Pathway | Fc epsilon RI signaling pathway;KEGG PATHWAY;hsa04664 |
Pathway | Pancreatic secretion;KEGG PATHWAY;hsa04972 |
Pathway | Toxoplasmosis;KEGG PATHWAY;hsa05145 |
Pathway | Glypican 1 network;PID Curated;200021 |
Pathway | phospholipases;BioCyc;LIPASYN-PWY |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Glycerophospholipid metabolism;KEGG PATHWAY;hsa00564 |
Pathway | alpha-Linolenic acid metabolism;KEGG PATHWAY;hsa00592 |
Pathway | Long-term depression;KEGG PATHWAY;hsa04730 |
Pathway | Ether lipid metabolism;KEGG PATHWAY;hsa00565 |
Pathway | Linoleic acid metabolism;KEGG PATHWAY;hsa00591 |
Pathway | GnRH signaling pathway;KEGG PATHWAY;hsa04912 |
Pathway | Arachidonic acid metabolism;KEGG PATHWAY;hsa00590 |
Disease | Drug abuse;FunDO |
Disease | Embryoma;FunDO |
Disease | PSYCH;GAD |
Disease | Diabetes mellitus;FunDO |
Disease | Cystic fibrosis;FunDO |
Disease | Vascular dementia;FunDO |
Disease | Colorectal cancer;OMIM |
Disease | Schizophrenia;FunDO |
Disease | Dental plaque;FunDO |
Disease | Cholelithiasis;FunDO |
Disease | Stroke;FunDO |
Disease | Stomach cancer;FunDO |
Disease | Alzheimer's disease;FunDO |
Disease | affective disorder;GAD |
Disease | Neoplasm metastasis;FunDO |
Disease | Atherosclerosis;FunDO |
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External Links |
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Links to Entrez Gene | 5320 |
Links to all GeneRIF Items | 5320 |
Links to iHOP | 5320 |
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Sequence Information |
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Nucleotide Sequence |
>5320 : length: 435 atgaagaccctcctactgttggcagtgatcatgatctttggcctactgcaggcccatggg aatttggtgaatttccacagaatgatcaagttgacgacaggaaaggaagccgcactcagt tatggcttctacggctgccactgtggcgtgggtggcagaggatcccccaaggatgcaacg gatcgctgctgtgtcactcatgactgttgctacaaacgtctggagaaacgtggatgtggc accaaatttctgagctacaagtttagcaactcggggagcagaatcacctgtgcaaaacag gactcctgcagaagtcaactgtgtgagtgtgataaggctgctgccacctgttttgctaga aacaagacgacctacaataaaaagtaccagtactattccaataaacactgcagagggagc acccctcgttgctga |
Protein Sequence |
>5320 : length: 144 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR NKTTYNKKYQYYSNKHCRGSTPRC |