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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 54206 |
Name | ERRFI1 |
Synonym | GENE-33|MIG-6|MIG6|RALT;ERBB receptor feedback inhibitor 1;ERRFI1;ERBB receptor feedback inhibitor 1 |
Definition | mitogen-inducible gene 6 protein|receptor-associated late transducer |
Position | 1p36 |
Gene Type | protein-coding |
Source | Count: 3; Pubmed_search,Generif,UniProt |
Literature support | Count: 5 PubMed records as below. |
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Evidence Status |
Description |
potential | "multifaceted genomic evaluation of glioblastoma establishes ERRFI1 as a potential candidate tumor suppressor gene and TACC3 as a potential oncogene, and provides insight on targets for oncogenic pathway-based therapy". |
reviewed | Evidence that MIG-6 is a tumor-suppressor gene. |
reviewed | Results indicate that Mig6 is a specific negative regulator of Egfr signaling in skin morphogenesis and is a novel tumor suppressor of Egfr-dependent carcinogenesis. |
reviewed | Mitogen-inducible gene-6 is a multifunctional adaptor protein with tumor suppressor-like activity in papillary thyroid cancer. |
reviewed | "Review highlights important roles of Mig-6 in regulating stress response, maintaining homeostasis in tissues like joints or cardiac muscle, and functioning as a tumor suppressor." |
| More detail of all 5 literatures about ERRFI1 | |
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External Links |
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Links to Entrez Gene | 54206 |
Links to all GeneRIF Items | 54206 |
Links to iHOP | 54206 |
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Sequence Information |
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Nucleotide Sequence |
>54206 : length: 1389 atgtcaatagcaggagttgctgctcaggagatcagagtcccattaaaaactggatttcta cataatggccgagccatggggaatatgaggaagacctactggagcagtcgcagtgagttt aaaaacaactttttaaatattgacccgataaccatggcctacagtctgaactcttctgct caggagcgcctaataccacttgggcatgcttccaaatctgctccgatgaatggccactgc tttgcagaaaatggtccatctcaaaagtccagcttgccccctcttcttattcccccaagt gaaaacttgggaccacatgaagaggatcaagttgtatgtggttttaagaaactcacagtg aatggggtttgtgcttccacccctccactgacacccataaaaaactccccttcccttttc ccctgtgcccctctttgtgaacggggttctaggcctcttccaccgttgccaatctctgaa gccctctctctggatgacacagactgtgaggtggaattcctaactagctcagatacagac ttccttttagaagactctacactttctgatttcaaatatgatgttcctggcaggcgaagc ttccgtgggtgtggacaaatcaactatgcatattttgataccccagctgtttctgcagca gatctcagctatgtgtctgaccaaaatggaggtgtcccagatccaaatcctcctccacct cagacccaccgaagattaagaaggtctcattcgggaccagctggctcctttaacaagcca gccataaggatatccaactgttgtatacacagagcttctcctaactccgatgaagacaaa cctgaggttccccccagagttcccatacctcctagaccagtaaagccagattatagaaga tggtcagcagaagttacttcgagcacctatagtgatgaagacaggcctcccaaagtaccg ccaagagaacctttgtcaccgagtaactcgcgcacaccgagtcccaaaagccttccgtct tacctcaatggggtcatgcccccgacacagagctttgcccctgatcccaagtatgtcagc agcaaagcactgcaaagacagaacagcgaaggatctgccagtaaggttccttgcattctg cccattattgaaaatgggaagaaggttagttcaacacattattacctactacctgaacga ccaccatacctggacaaatatgaaaaattttttagggaagcagaagaaacaaatggaggc gcccaaatccagccattacctgctgactgcggtatatcttcagccacagaaaagccagac tcaaaaacaaaaatggatctgggtggccacgtgaagcgtaaacatttatcctatgtggtt tctccttag |
Protein Sequence |
>54206 : length: 462 MSIAGVAAQEIRVPLKTGFLHNGRAMGNMRKTYWSSRSEFKNNFLNIDPITMAYSLNSSA QERLIPLGHASKSAPMNGHCFAENGPSQKSSLPPLLIPPSENLGPHEEDQVVCGFKKLTV NGVCASTPPLTPIKNSPSLFPCAPLCERGSRPLPPLPISEALSLDDTDCEVEFLTSSDTD FLLEDSTLSDFKYDVPGRRSFRGCGQINYAYFDTPAVSAADLSYVSDQNGGVPDPNPPPP QTHRRLRRSHSGPAGSFNKPAIRISNCCIHRASPNSDEDKPEVPPRVPIPPRPVKPDYRR WSAEVTSSTYSDEDRPPKVPPREPLSPSNSRTPSPKSLPSYLNGVMPPTQSFAPDPKYVS SKALQRQNSEGSASKVPCILPIIENGKKVSSTHYYLLPERPPYLDKYEKFFREAEETNGG AQIQPLPADCGISSATEKPDSKTKMDLGGHVKRKHLSYVVSP |