Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

54739

Name

XAF1

Synonym

BIRC4BP|HSXIAPAF1|XIAPAF1;XIAP associated factor 1;XAF1;XIAP associated factor 1

Definition

BIRC4 binding protein|BIRC4-binding protein|XIAP-associated factor 1

Position

17p13.1

Gene Type

protein-coding

Source

Count: 3; Pubmed_search,Generif,UniProt

Literature support

Count: 3 PubMed records as below.

Evidence Status

Description

reviewed

[5-azacytidine treatment induces tumor suppressor gene XAF1 expression and inhibits proliferation in myeloma cells].

reviewed

XAF1 may have a role as a tumor suppressor gene in advanced bladder cancer treated with neoadjuvant chemotherapy.

potential

"Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas."
More detail of all 3 literatures about XAF1

External Links

Links to Entrez Gene

54739

Links to all GeneRIF Items

54739

Links to iHOP

54739

Sequence Information

Nucleotide Sequence

>54739 : length: 906
atggaaggagacttctcggtgtgcaggaactgtaaaagacatgtagtctctgccaacttc
accctccatgaggcttactgcctgcggttcctggtcctgtgtccggagtgtgaggagcct
gtccccaaggaaaccatggaggagcactgcaagcttgagcaccagcaggttgggtgtacg
atgtgtcagcagagcatgcagaagtcctcgctggagtttcataaggccaatgagtgccag
gagcgccctgttgagtgtaagttctgcaaactggacatgcagctcagcaagctggagctc
cacgagtcctactgtggcagccggacagagctctgccaaggctgtggccagttcatcatg
caccgcatgctcgcccagcacagagatgtctgtcgcagtgaacaggcccagctcgggaaa
ggggaaagaatttcagctcctgaaagggaaatctactgtcattattgcaaccaaatgatt
ccagaaaataagtatttccaccatatgggtaaatgttgtccagactcagagtttaagaaa
cactttcctgttggaaatccagaaattcttccttcatctcttccaagtcaagctgctgaa
aatcaaacttccacgatggagaaagatgttcgtccaaagacaagaagtataaacagattt
cctcttcattctgaaagttcatcaaagaaagcaccaagaagcaaaaacaaaaccttggat
ccacttttgatgtcagagcccaagcccaggaccagctcccctagaggagataaagcagcc
tatgacattctgaggagatgttctcagtgtggcatcctgcttcccctgccgatcctaaat
caacatcaggagaaatgccggtggttagcttcatcaaaaggaaaacaagtgagaaatttc
agctag

Protein Sequence

>54739 : length: 301
MEGDFSVCRNCKRHVVSANFTLHEAYCLRFLVLCPECEEPVPKETMEEHCKLEHQQVGCT
MCQQSMQKSSLEFHKANECQERPVECKFCKLDMQLSKLELHESYCGSRTELCQGCGQFIM
HRMLAQHRDVCRSEQAQLGKGERISAPEREIYCHYCNQMIPENKYFHHMGKCCPDSEFKK
HFPVGNPEILPSSLPSQAAENQTSTMEKDVRPKTRSINRFPLHSESSSKKAPRSKNKTLD
PLLMSEPKPRTSSPRGDKAAYDILRRCSQCGILLPLPILNQHQEKCRWLASSKGKQVRNF
S



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