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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 54904 |
Name | WHSC1L1 |
Synonym | NSD3|pp14328;Wolf-Hirschhorn syndrome candidate 1-like 1;WHSC1L1;Wolf-Hirschhorn syndrome candidate 1-like 1 |
Definition | WHSC1-like 1 isoform 9 with methyltransferase activity to lysine|WHSC1-like protein 1|histone-lysine N-methyltransferase NSD3|nuclear SET domain-containing protein 3|protein whistle |
Position | 8p11.2 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | NSD3L depletion increased the invasiveness of MDA-MB-231 breast cancer cells indicating that NSD3L normally restrain cellular metastatic potential. Together the presented data indicates that NSD3L is a candidate tumor suppressor. |
| More detail of all 1 literatures about WHSC1L1 | |
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Pathways and Diseases |
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Pathway | Lysine degradation;KEGG PATHWAY;hsa00310 |
Disease | Leukemia, acute myeloid;OMIM |
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External Links |
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Links to Entrez Gene | 54904 |
Links to all GeneRIF Items | 54904 |
Links to iHOP | 54904 |
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Sequence Information |
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Nucleotide Sequence |
>54904 : length: 1938 atggatttctctttctctttcatgcaagggatcatgggaaacacaattcagcaaccacct caactcattgactccgccaacatccgtcaggaggatgcctttgataacaacagtgacatt gctgaagatggtggccagacaccatatgaagctactttgcagcaaggctttcagtaccca gctacaacagaagatcttcctccactcacaaatgggtatccatcatcaatcagtgtgtat gaaactcaaaccaaataccagtcatataatcagtatcctaatgggtcagccaatggcttt ggtgcagttagaaactttagccccactgactattatcattcagaaattccaaacacaaga ccacatgaaattctggaaaaaccttcccctccacagccaccacctcctccttcggtacca caaactgtgattccaaagaagactggctcacctgaaattaaactaaaaataaccaaaact atccagaatggcagggaattgtttgagtcttccctttgtggagaccttttaaatgaagta caggcaagtgagcacacgaaatcaaagcatgaaagcagaaaagaaaagaggaaaaaaagc aacaagcatgactcatcaagatctgaagagcgcaagtcacacaaaatccccaaattagaa ccagaggaacaaaatagaccaaatgagagggttgacactgtatcagaaaaaccaagggaa gaaccagtactaaaagaggaagccccagttcagccaatactatcttctgttccaacaacg gaagtgtccactggtgttaagtttcaggttggcgatcttgtgtggtccaaggtgggaacc tatccttggtggccttgtatggtttcaagtgatccccagcttgaggttcatactaaaatt aacacaagaggtgcccgagaatatcatgtccagttttttagcaaccagccagagagggcg tgggttcatgaaaaacgggtacgagagtataaaggtcataaacagtatgaagaattactg gctgaggcaaccaaacaagccagcaatcactctgagaaacaaaagattcggaaaccccga cctcagagagaacgtgctcagtgggatattggcattgcccatgcagagaaagcattgaaa atgactcgagaagaaagaatagaacagtatacttttatttacattgataaacagcctgaa gaggctttatcccaagcaaaaaagagtgttgcctccaaaaccgaagttaaaaaaacccga cgaccaagatctgtgctgaatactcagccagaacagaccaatgcaggggaggtggcctcc tcactctcaagtactgaaattcggagacatagccagaggcggcacacaagtgcggaagag gaagagccaccgcctgttaaaatagcctggaaaactgcggcagcaaggaaatccttacca gcttccattacgatgcacaaagggagcctggatttgcagaagtgtaacatgtctccagtt gtgaaaattgaacaagtgtttgctcttcagaatgctacaggggatgggaaatttatcgat caatttgtttattcaacaaagggaattggtaacaaaacagaaataagtgtcagggggcaa gacaggcttataatttctacaccaaaccagagaaatgaaaagccaacgcagagtgtatca tctcctgaagcaacatctggttctacaggctcagtagaaaagaagcaacagagaagatca attagaactcgttctgaatcagagaaatccactgaggttgtgccaaagaagaagatcaaa aaggagcaggttgaaacagttcctcaggctacagtgaagactggattacagaaagggtcg gcggaccggggagtgcagggctctgtcagattcagtgacagctccgtctccgcagcgatt gaggaaactgtggactga |
Protein Sequence |
>54904 : length: 645 MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYP ATTEDLPPLTNGYPSSISVYETQTKYQSYNQYPNGSANGFGAVRNFSPTDYYHSEIPNTR PHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPRE EPVLKEEAPVQPILSSVPTTEVSTGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKI NTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTR RPRSVLNTQPEQTNAGEVASSLSSTEIRRHSQRRHTSAEEEEPPPVKIAWKTAAARKSLP ASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIK KEQVETVPQATVKTGLQKGSADRGVQGSVRFSDSSVSAAIEETVD |