|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 55193 |
Name | PBRM1 |
Synonym | BAF180|PB1;polybromo 1;PBRM1;polybromo 1 |
Definition | BRG1-associated factor 180|polybromo-1D|protein polybromo-1 |
Position | 3p21 |
Gene Type | protein-coding |
Source | Count: 3; Pubmed_search,Generif,UniProt |
Literature support | Count: 3 PubMed records as below. |
|
Evidence Status |
Description |
reviewed | BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer. |
potential | The 3p21 candidate tumor suppressor gene BAF180 is normally expressed in human lung cancer. |
reviewed | "cDNA cloning; the hPB1 gene is located on chromosome 3p21, where the tumor suppressor genes for breast, lung and kidney cancers have been mapped". |
| More detail of all 3 literatures about PBRM1 | |
|
External Links |
|
Links to Entrez Gene | 55193 |
Links to all GeneRIF Items | 55193 |
Links to iHOP | 55193 |
|
Sequence Information |
|
Nucleotide Sequence |
>55193 : length: 4809 atgggttccaagagaagaagagctacctccccttccagcagtgtcagcggggactttgat gatgggcaccattctgtgtcaacaccaggcccaagcaggaaaaggaggagactttccaat cttccaactgtagatcctattgccgtgtgccatgaactctataataccatccgagactat aaggatgaacagggcagacttctctgtgagctcttcattagggcaccaaagcgaagaaat caaccagactattatgaagtggtttctcagcccattgacttgatgaaaatccaacagaaa ctaaaaatggaagagtatgatgatgttaatttgctgactgctgacttccagcttcttttt aacaatgcaaagtcctattataagccagattctcctgaatataaagccgcttgcaaactc tgggatttgtaccttcgaacaagaaatgagtttgttcagaaaggagaagcagatgacgaa gatgatgatgaagatgggcaagacaatcagggcacagtgactgaaggatcttctccagct tacttgaaggagatcctggagcagcttcttgaagccatagttgtagctacaaatccatca ggacgtctcattagcgaactttttcagaaactgccttctaaagtgcaatatccagattat tatgcaataattaaggagcctatagatctcaagaccattgcccagaggatacagaatgga agctacaaaagtattcatgcaatggccaaagatatagatctcctcgcaaaaaatgccaaa acttataatgagcctggctctcaagtattcaaggatgcaaattcaattaaaaaaatattt tatatgaaaaaggctgaaattgaacatcatgaaatggctaagtcaagtcttcgaatgagt aataaaagagcagtacaaggaggtcgtttatcagcaattacaatggcacttcaatatggc tcagaaagtgaagaagatgctgctttagctgctgcacgctatgaagagggagagtcagaa gcagaaagcatcacttcctttatggatgtttcaaatcctttttatcagctttatgacaca gttaggagttgtcggaataaccaagggcagctaatagctgaacctttttaccatttgcct tcaaagaaaaaataccctgattattaccagcaaattaaaatgcccatatcactacaacag atccgaacaaaactgaagaatcaagaatatgaaactttagatcatttggagtgtgatctg aatttaatgtttgaaaatgccaaacgctataatgtgcccaattcagccatctacaagcga gttctaaaattgcagcaagttatgcaggcaaagaagaaagagcttgccaggagagacgat atcgaggacggagacagcatgatctcttcagccacctctgatactggtagtgccaaaaga aaaagtaaaaagaacataagaaagcagcgaatgaaaatcttattcaatgttgttcttgaa gctcgagagccaggttcaggcagaagactttgtgacctatttatggttaaaccatccaaa aaggactatcctgattattataaaatcatcttggagccaatggacttgaaaataattgag cataacatccgcaatgacaaatatgctggtgaagagggaatgatagaagacatgaagctg atgttccggaatgccaggcactataatgaggagggctcccaggtttataatgatgcacat atcctggagaagttactcaaggagaaaaggaaagagctgggcccactgcctgatgatgat gacatggcttctcccaaactcaagctgagtaggaagagtggcatttctcctaaaaaatca aaatacatgactccaatgcagcagaaactaaatgaggtctatgaagctgtaaagaactat actgataagaggggtcgccgcctcagtgccatatttctgaggcttccctctagatctgag ttgcctgactactatctgactattaaaaagcccatggacatggaaaaaattcgaagtcac atgatggccaacaagtaccaagatattgactctatggttgaggactttgtcatgatgttt aataatgcctgtacatacaatgagccggagtctttgatctacaaagatgctcttgttcta cacaaagtcctgcttgaaacacgcagagacctggagggagatgaggactctcatgtccca aatgtgactttgctgattcaagagcttatccacaatctttttgtgtcagtcatgagtcat caggatgatgagggaagatgctacagcgattctttagcagaaattcctgctgtggatccc aactttcctaacaaaccaccccttacatttgacataattaggaagaatgttgaaaataat cgctaccgtcggcttgatttatttcaagagcatatgtttgaagtattggaacgagcaaga aggatgaatcggacagattcagaaatatatgaagatgcagtagaacttcagcagtttttt attaaaattcgtgatgaactctgcaaaaatggagagattcttctttcaccggcactcagc tataccacaaaacatttgcataatgatgtggagaaagagagaaaggaaaaattgccaaaa gaaatagaggaagataaactaaaacgagaagaagaaaaaagagaagctgaaaagagtgaa gattcctctggtgctgcaggcctctcaggcttacatcgcacatacagccaggactgtagc tttaaaaacagcatgtaccatgttggagattacgtctatgtggaacctgcagaggccaac ctacaaccacatatcgtctgtattgaaagactgtgggaggattcagctggtgaaaaatgg ttgtatggctgttggttttaccgaccaaatgaaacattccacctggctacacgaaaattt ctagaaaaagaagtttttaagagtgactattacaacaaagttccagttagtaaaattcta ggcaagtgtgtggtcatgtttgtcaaggaatactttaagttatgcccagaaaacttccga gatgaggatgtttttgtctgtgaatcacggtattctgccaaaaccaaatcttttaagaaa attaaactgtggaccatgcccatcagctcagtcaggtttgtccctcgggatgtgcctctg cctgtggttcgcgtggcctctgtatttgcaaatgcagataaaggtgatgatgagaagaat acagacaactcagaggacagtcgagctgaagacaattttaacttggaaaaggaaaaagaa gatgtccctgtggaaatgtccaatggtgaaccaggttgccactactttgagcagctccat tacaatgacatgtggctgaaggttggcgactgtgtcttcatcaagtcccatggcctggtg cgtcctcgtgtgggcagaattgaaaaagtatgggttcgagatggagctgcatatttttat ggccccatcttcattcacccagaagaaacagagcatgagcccacaaaaatgttctacaaa aaagaagtatttctgagtaatctggaagaaacctgccccatgacatgtattctcggaaag tgtgctgtgttgtcattcaaggacttcctctcctgcaggccaactgaaataccagaaaat gacattctgctttgtgagagccgctacaatgagagcgacaagcagatgaagaaattcaaa ggattgaagaggttttcactctctgctaaagtggtagatgatgaaatttactacttcaga aaaccaattgttcctcagaaggagccatcacctttgctggaaaagaagatccagttgcta gaagctaaatttgccgagttagaaggtggagatgatgatattgaagagatgggagaagaa gatagtgaggtcattgaacctccttctctacctcagcttcagacccccctggccagtgag ctggacctcatgccctacacacccccacagtctaccccaaagtctgccaaaggcagtgca aagaaggaaggctccaaacggaaaatcaacatgagtggctacatcctgttcagcagtgag atgagggctgtgattaaggcccaacacccagactactctttcggggagctcagccgcctg gtggggacagaatggagaaatcttgagacagccaagaaagcagaatatgaaggcatgatg ggtggctatccgccaggccttccacctttgcagggcccagttgatggccttgttagcatg ggcagcatgcagccacttcaccctggggggcctccaccccaccatcttccgccaggtgtg cctggcctcccgggcatcccaccaccgggtgtgatgaaccaaggagtggcccctatggta gggactccagcaccaggtggaagtccatatggacaacaggtgggagttttggggcctcca gggcagcaggcaccacctccatatcccggcccacatccagctggaccccctgtcatacag cagccaacaacacccatgtttgtagctcccccaccaaagacccagcggcttcttcactca gaggcctacctgaaatacattgaaggactcagtgcggagtccaacagcattagcaagtgg gatcagacactggcagctcgaagacgcgacgtccatttgtcgaaagaacaggagagccgc ctaccctctcactggctgaaaagcaaaggggcccacaccaccatggcagatgccctctgg cgccttcgagatttgatgctccgggacaccctcaacattcgccaagcatacaacctagaa aatgtttaa |
Protein Sequence |
>55193 : length: 1602 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMS NKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDT VRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDL NLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKR KSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIE HNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDD DMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSE LPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL HKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDP NFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFF IKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSE DSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKW LYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFR DEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKN TDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLV RPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGK CAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFR KPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASE LDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRL VGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGV PGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQ QPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESR LPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV |