Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

5533

Name

PPP3CC

Synonym

CALNA3|CNA3|PP2Bgamma;protein phosphatase 3, catalytic subunit, gamma isozyme;PPP3CC;protein phosphatase 3, catalytic subunit, gamma isozyme

Definition

CAM-PRP catalytic subunit|calcineurin, testis-specific catalytic subunit|calmodulin-dependent calcineurin A subunit gamma isoform|protein phosphatase 2B, catalytic subunit, gamma isoform|protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isofor

Position

8p21.3

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

potential

These data strongly support a recent proposal that a segment at 8p21.3 contains crucial prostate cancer tumor suppressors.
More detail of all 1 literatures about PPP3CC

Pathways and Diseases

Pathway

Apoptosis;Reactome;REACT:578

Pathway

B cell receptor signaling pathway;KEGG PATHWAY;hsa04662

Pathway

signaling pathway from g-protein families;PID BioCarta;100153

Pathway

MAPK signaling pathway;KEGG PATHWAY;hsa04010

Pathway

effects of calcineurin in keratinocyte differentiation;PID BioCarta;100222

Pathway

Alzheimer's disease;KEGG PATHWAY;hsa05010

Pathway

role of mef2d in t-cell apoptosis;PID BioCarta;100109

Pathway

t cell receptor signaling pathway;PID BioCarta;100022

Pathway

regulation of pgc-1a;PID BioCarta;100075

Pathway

Wnt signaling pathway;KEGG PATHWAY;hsa04310

Pathway

Opioid Signalling;Reactome;REACT:15295

Pathway

Apoptosis;KEGG PATHWAY;hsa04210

Pathway

T cell receptor signaling pathway;KEGG PATHWAY;hsa04660

Pathway

T cell activation;PANTHER;P00053

Pathway

Axon guidance;KEGG PATHWAY;hsa04360

Pathway

Amyotrophic lateral sclerosis (ALS);KEGG PATHWAY;hsa05014

Pathway

nitric oxide signaling pathway;PID BioCarta;100092

Pathway

VEGF signaling pathway;KEGG PATHWAY;hsa04370

Pathway

Long-term potentiation;KEGG PATHWAY;hsa04720

Pathway

Wnt signaling pathway;PANTHER;P00057

Pathway

Calcium signaling pathway;KEGG PATHWAY;hsa04020

Pathway

bcr signaling pathway;PID BioCarta;100227

Pathway

fmlp induced chemokine gene expression in hmc-1 cells;PID BioCarta;100162

Pathway

nfat and hypertrophy of the heart ;PID BioCarta;100098

Pathway

Oocyte meiosis;KEGG PATHWAY;hsa04114

Pathway

endocytotic role of ndk phosphins and dynamin;PID BioCarta;100099

Pathway

Natural killer cell mediated cytotoxicity;KEGG PATHWAY;hsa04650

Disease

HIV-1 control;NHGRI

Disease

PSYCH;GAD

Disease

schizophrenia;GAD

External Links

Links to Entrez Gene

5533

Links to all GeneRIF Items

5533

Links to iHOP

5533

Sequence Information

Nucleotide Sequence

>5533 : length: 1539
atgtccgggaggcgcttccacctctccaccaccgaccgcgtcatcaaagctgtccccttt
cctccaacccaacggcttactttcaaggaagtatttgagaatgggaaacctaaagttgat
gttttaaaaaaccatttggtaaaggaaggacgactggaagaggaagtagccttaaagata
atcaatgatggggctgccatcctgaggcaagagaagactatgatagaagtagatgctcca
atcacagtatgtggtgatattcatggacaattctttgacctaatgaagttatttgaagtt
ggaggatcacctagtaacacacgctacctctttctgggtgactatgtggacagaggctat
ttcagtatagagtgtgtgctgtatttatggagtttaaagattaatcatcccaaaacattg
tttctgcttcggggaaatcatgaatgcaggcatcttacagactatttcaccttcaaacag
gaatgtcgaatcaaatattcggaacaggtgtatgatgcctgtatggagacatttgactgt
cttcctcttgctgccctcttaaaccagcagtttctctgtgtacatggaggaatgtcacct
gaaattacttctttagatgacattaggaaattagacaggtttacggaacctcccgccttt
ggacctgtgtgtgacctgctttggtctgatccctcagaggattatggcaatgagaagacc
ttggagcactatacccacaacactgtccgagggtgctcttatttctacagttaccctgca
gtttgtgaatttttgcagaacaataatttactatcaattatcagagcccatgaagcccaa
gatgctgggtatcgaatgtacaggaagagccaagccacaggctttccatcacttattaca
attttctctgcccccaattacctagatgtctataacaataaagctgctgtgttgaaatat
gaaaacaatgtcatgaatatcaggcagtttaactgttctccacacccctactggcttcca
aactttatggatgttttcacatggtctttgccttttgttggggaaaaagtcacagagatg
ctggtaaatgtgctcaacatatgctctgatgacgaactgatttctgatgatgaagcagaa
ggaagcactacagttcgtaaggagatcatcaggaataagatcagagccattgggaagatg
gcacgggtcttttcaattcttcggcaagaaagtgagagtgtgctgactctcaagggcctg
actcccacaggcacactccctctgggcgtcctctcaggaggcaagcagactatcgagaca
gccacagtagaagcggtagaggcccgggaagccatcagagggttctcgcttcagcacaag
atccggagttttgaagaagcgcgaggtctggaccgaattaatgagcgaatgccaccccga
aaggatagcatacacgctggtgggccaatgaaatctgtaacctcagcacactcacatgct
gcgcacaggagcgaccaagggaagaaagcccattcatga

Protein Sequence

>5533 : length: 512
MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKI
INDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY
FSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDC
LPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKT
LEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLIT
IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM
LVNVLNICSDDELISDDEAEGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGL
TPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPR
KDSIHAGGPMKSVTSAHSHAAHRSDQGKKAHS



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