Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

55384

Name

MEG3

Synonym

FP504|GTL2|LINC00023|NCRNA00023|PRO0518|PRO2160|prebp1;maternally expressed 3 (non-protein coding);MEG3;maternally expressed 3 (non-protein coding)

Definition

-

Position

14q32

Gene Type

miscRNA

Source

Count: 2; Pubmed_search,Generif

Literature support

Count: 3 PubMed records as below.

Evidence Status

Description

reviewed

MEG3 noncoding RNA: a tumor suppressor.

potential

MEG3 inhibits colony formation in meningioma cells. MEG3 stimulates p53-mediated transactivation in these cell lines. Data are consistent with the hypothesis that MEG3 may be a tumor suppressor gene at chromosome 14q32 involved in meningioma progression.

potential

"MEG3 non-coding RNA may function as a tumor suppressor, whose action is mediated by both p53-dependent and p53-independent pathways".

reviewed

MEG3 noncoding RNA: a tumor suppressor. These lines of evidence strongly suggest that MEG3 functions as a novel lncRNA tumor suppressor.

reviewed

"In this review, author summarized the gene as tumor suppressor in table 2."

reviewed

"Therefore, these data are consistent with the hypothesis that MEG3, which encodes a noncoding RNA, may be a tumor suppressor gene at chromosome 14q32 involved in meningioma progression via a novel mechanism."
More detail of all 3 literatures about MEG3

External Links

Links to Entrez Gene

55384

Links to all GeneRIF Items

55384

Links to iHOP

55384

Sequence Information

Nucleotide Sequence

>55384 : length: 1595
agcccctagcgcagacggcggagagcagagagggagcgcgccttggctcgctggccttgg
cggcggctcctcaggagagctggggcgcccacgagaggatccctcacccgggtctctcct
cagggatgacatcatccgtccacctccttgtcttcaaggaccacctcctctccatgctga
gctgctgccaaggggcctgctgcccatctacacctcacgagggcactaggagcacggttt
cctggatcccaccaacatacaaagcagccactcactgacccccaggaccaggatggcaaa
ggatgaagaggaccggaactgaccagccagctgtccctcttacctaaagacttaaaccaa
tgccctagtgagggggcattgggcattaagccctgacctttgctatgctcatactttgac
tctatgagtactttcctataagtctttgcttgtgttcacctgctagcaaactggagtgtt
tccctccccaagggggtgtcagtctttgtcgactgactctgtcatcacccttatgatgtc
ctgaatggaaggatccctttgggaaattctcaggagggggacctgggccaagggcttggc
cagcatcctgctggcaactccaaggccctgggtgggcttctggaatgagcatgctactga
atcaccaaaggcacgcccgacctctctgaagatcttcctatccttttctgggggaatggg
gtcgatgagagcaacctcctagggttgttgtgagaattaaatgagataaaagaggcctca
ggcaggatctggcatagaggaggtgatcagcaaatgtttgttgaaaaggtttgacaggtc
agtcccttcccacccctcttgcttgtcttacttgtcttatttattctccaacagcactcc
aggcagcccttgtccacgggctctccttgcatcagccaagcttcttgaaaggcctgtcta
cacttgctgtcttccttcctcacctccaatttcctcttcaacccactgcttcctgactcg
ctctactccgtggaagcacgctcacaaaggcacgtgggccgtggcccggctgggtcggct
gaagaactgcggatggaagctgcggaagaggccctgatggggcccaccatcccggaccca
agtcttcttcctggcgggcctctcgtctccttcctggtttgggcggaagccatcacctgg
atgcctacgtgggaagggacctcgaatgtgggaccccagcccctctccagctcgaaatcc
ctccacagccacggggacaccctgcacctattcccacgggacaggctggacccagagact
ctggacccggggcctccccttgagtagagacccgccctctgactgatggacgccgctgac
ctggggtcagacccgtgggctggacccctgcccaccccgcaggaaccctgaggcctaggg
gagctgttgagccttcagtgtctgcatgtgggaagtgggctccttcacctacctcacagg
gctgttgtgaggggcgctgtgatgcggttccaaagcacagggcttggcgcaccccactgt
gctctcaataaatgtgtttcctgtcttaacaaaaa



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