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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 55384 |
Name | MEG3 |
Synonym | FP504|GTL2|LINC00023|NCRNA00023|PRO0518|PRO2160|prebp1;maternally expressed 3 (non-protein coding);MEG3;maternally expressed 3 (non-protein coding) |
Definition | - |
Position | 14q32 |
Gene Type | miscRNA |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 3 PubMed records as below. |
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Evidence Status |
Description |
reviewed | MEG3 noncoding RNA: a tumor suppressor. |
potential | MEG3 inhibits colony formation in meningioma cells. MEG3 stimulates p53-mediated transactivation in these cell lines. Data are consistent with the hypothesis that MEG3 may be a tumor suppressor gene at chromosome 14q32 involved in meningioma progression. |
potential | "MEG3 non-coding RNA may function as a tumor suppressor, whose action is mediated by both p53-dependent and p53-independent pathways". |
reviewed | MEG3 noncoding RNA: a tumor suppressor. These lines of evidence strongly suggest that MEG3 functions as a novel lncRNA tumor suppressor. |
reviewed | "In this review, author summarized the gene as tumor suppressor in table 2." |
reviewed | "Therefore, these data are consistent with the hypothesis that MEG3, which encodes a noncoding RNA, may be a tumor suppressor gene at chromosome 14q32 involved in meningioma progression via a novel mechanism." |
| More detail of all 3 literatures about MEG3 | |
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External Links |
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Links to Entrez Gene | 55384 |
Links to all GeneRIF Items | 55384 |
Links to iHOP | 55384 |
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Sequence Information |
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Nucleotide Sequence |
>55384 : length: 1595 agcccctagcgcagacggcggagagcagagagggagcgcgccttggctcgctggccttgg cggcggctcctcaggagagctggggcgcccacgagaggatccctcacccgggtctctcct cagggatgacatcatccgtccacctccttgtcttcaaggaccacctcctctccatgctga gctgctgccaaggggcctgctgcccatctacacctcacgagggcactaggagcacggttt cctggatcccaccaacatacaaagcagccactcactgacccccaggaccaggatggcaaa ggatgaagaggaccggaactgaccagccagctgtccctcttacctaaagacttaaaccaa tgccctagtgagggggcattgggcattaagccctgacctttgctatgctcatactttgac tctatgagtactttcctataagtctttgcttgtgttcacctgctagcaaactggagtgtt tccctccccaagggggtgtcagtctttgtcgactgactctgtcatcacccttatgatgtc ctgaatggaaggatccctttgggaaattctcaggagggggacctgggccaagggcttggc cagcatcctgctggcaactccaaggccctgggtgggcttctggaatgagcatgctactga atcaccaaaggcacgcccgacctctctgaagatcttcctatccttttctgggggaatggg gtcgatgagagcaacctcctagggttgttgtgagaattaaatgagataaaagaggcctca ggcaggatctggcatagaggaggtgatcagcaaatgtttgttgaaaaggtttgacaggtc agtcccttcccacccctcttgcttgtcttacttgtcttatttattctccaacagcactcc aggcagcccttgtccacgggctctccttgcatcagccaagcttcttgaaaggcctgtcta cacttgctgtcttccttcctcacctccaatttcctcttcaacccactgcttcctgactcg ctctactccgtggaagcacgctcacaaaggcacgtgggccgtggcccggctgggtcggct gaagaactgcggatggaagctgcggaagaggccctgatggggcccaccatcccggaccca agtcttcttcctggcgggcctctcgtctccttcctggtttgggcggaagccatcacctgg atgcctacgtgggaagggacctcgaatgtgggaccccagcccctctccagctcgaaatcc ctccacagccacggggacaccctgcacctattcccacgggacaggctggacccagagact ctggacccggggcctccccttgagtagagacccgccctctgactgatggacgccgctgac ctggggtcagacccgtgggctggacccctgcccaccccgcaggaaccctgaggcctaggg gagctgttgagccttcagtgtctgcatgtgggaagtgggctccttcacctacctcacagg gctgttgtgaggggcgctgtgatgcggttccaaagcacagggcttggcgcaccccactgt gctctcaataaatgtgtttcctgtcttaacaaaaa |