Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

554213

Name

MIR449A

Synonym

MIRN449|MIRN449A|hsa-mir-449;microRNA 449a;MIR449A;microRNA 449a

Definition

-

Position

5q11.2

Gene Type

miscRNA

Source

Count: 1; Generif

Literature support

Count: 2 PubMed records as below.

Evidence Status

Description

reviewed

"Data indicate that miR-449a is a miRNA component of the Rb pathway and its tumor suppressor-like effects, in part, depends on Rb status in prostate cancer cells."

reviewed

"reveals a tumor suppressor function of miR-449a/b through regulating Rb/E2F1 activity, and suggests that escape from this regulation through an aberrant epigenetic event contributes to E2F1 deregulation and unrestricted proliferation in human cancer".
More detail of all 2 literatures about MIR449A

External Links

Links to Entrez Gene

554213

Links to all GeneRIF Items

554213

Links to iHOP

554213

Sequence Information

Nucleotide Sequence

>554213 : length: 22
tggcagtgtattgttagctggt



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