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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 5654 |
Name | HTRA1 |
Synonym | ARMD7|HtrA|L56|ORF480|PRSS11;HtrA serine peptidase 1;HTRA1;HtrA serine peptidase 1 |
Definition | IGFBP5-protease|high-temperature requirement A serine peptidase 1|protease, serine, 11 (IGF binding)|serine protease HTRA1 |
Position | 10q26.3 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 3 PubMed records as below. |
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Evidence Status |
Description |
reviewed | Intracellular localization of the tumor suppressor HtrA1/Prss11 and its association with HPV16 E6 and E7 proteins. |
potential | There is a significant decrease in HtrA1 mRNA in malignant ovarian tumors compared to benign; HtrA1 may function as a tumor suppressor. |
potential | HTRA1 is a candidate tumor suppressor in ovarian cancer. |
| More detail of all 3 literatures about HTRA1 | |
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External Links |
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Links to Entrez Gene | 5654 |
Links to all GeneRIF Items | 5654 |
Links to iHOP | 5654 |
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Sequence Information |
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Nucleotide Sequence |
>5654 : length: 1443 atgcagatcccgcgcgccgctcttctcccgctgctgctgctgctgctggcggcgcccgcc tcggcgcagctgtcccgggccggccgctcggcgcctttggccgccgggtgcccagaccgc tgcgagccggcgcgctgcccgccgcagccggagcactgcgagggcggccgggcccgggac gcgtgcggctgctgcgaggtgtgcggcgcgcccgagggcgccgcgtgcggcctgcaggag ggcccgtgcggcgaggggctgcagtgcgtggtgcccttcggggtgccagcctcggccacg gtgcggcggcgcgcgcaggccggcctctgtgtgtgcgccagcagcgagccggtgtgcggc agcgacgccaacacctacgccaacctgtgccagctgcgcgccgccagccgccgctccgag aggctgcaccggccgccggtcatcgtcctgcagcgcggagcctgcggccaagggcaggaa gatcccaacagtttgcgccataaatataactttatcgcggacgtggtggagaagatcgcc cctgccgtggttcatatcgaattgtttcgcaagcttccgttttctaaacgagaggtgccg gtggctagtgggtctgggtttattgtgtcggaagatggactgatcgtgacaaatgcccac gtggtgaccaacaagcaccgggtcaaagttgagctgaagaacggtgccacttacgaagcc aaaatcaaggatgtggatgagaaagcagacatcgcactcatcaaaattgaccaccagggc aagctgcctgtcctgctgcttggccgctcctcagagctgcggccgggagagttcgtggtc gccatcggaagcccgttttcccttcaaaacacagtcaccaccgggatcgtgagcaccacc cagcgaggcggcaaagagctggggctccgcaactcagacatggactacatccagaccgac gccatcatcaactatggaaactcgggaggcccgttagtaaacctggacggtgaagtgatt ggaattaacactttgaaagtgacagctggaatctcctttgcaatcccatctgataagatt aaaaagttcctcacggagtcccatgaccgacaggccaaaggaaaagccatcaccaagaag aagtatattggtatccgaatgatgtcactcacgtccagcaaagccaaagagctgaaggac cggcaccgggacttcccagacgtgatctcaggagcgtatataattgaagtaattcctgat accccagcagaagctggtggtctcaaggaaaacgacgtcataatcagcatcaatggacag tccgtggtctccgccaatgatgtcagcgacgtcattaaaagggaaagcaccctgaacatg gtggtccgcaggggtaatgaagatatcatgatcacagtgattcccgaagaaattgaccca tag |
Protein Sequence |
>5654 : length: 480 MQIPRAALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPARCPPQPEHCEGGRARD ACGCCEVCGAPEGAACGLQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVCG SDANTYANLCQLRAASRRSERLHRPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIA PAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEA KIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTT QRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKI KKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKAKELKDRHRDFPDVISGAYIIEVIPD TPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTLNMVVRRGNEDIMITVIPEEIDP |