Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

574411

Name

MIR451A

Synonym

MIR451|MIRN451|hsa-mir-451;microRNA 451a;MIR451A;microRNA 451a

Definition

-

Position

17q11.2

Gene Type

miscRNA

Source

Count: 2; Pubmed_search,Generif

Literature support

Count: 4 PubMed records as below.

Evidence Status

Description

reviewed

Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL.

reviewed

MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14).

potential

"This study, we performed a comprehensive analysis of putative human miRNA oncogenes and tumor suppressors. We found that miRNA oncogenes and tumor suppressors clearly show different patterns in function, evolutionary rate, expression, chromosome distribution, molecule size, free energy, transcription factors, and targets."

reviewed

MiRNA-451 plays a role as tumor suppressor in human glioma cells.
More detail of all 4 literatures about MIR451A

External Links

Links to Entrez Gene

574411

Links to all GeneRIF Items

574411

Links to iHOP

574411

Sequence Information

Nucleotide Sequence

>574411 : length: 22
aaaccgttaccattactgagtt



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