Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

57509

Name

MTUS1

Synonym

ATBP|ATIP|MP44|MTSG1;microtubule associated tumor suppressor 1;MTUS1;microtubule associated tumor suppressor 1

Definition

AT2 receptor-binding protein|AT2 receptor-interacting protein|AT2R binding protein|angiotensin-II type 2 receptor-interacting protein|erythroid differentiation-related|microtubule-associated tumor suppressor 1|mitochondrial tumor suppressor gene 1|transcr

Position

8p22

Gene Type

protein-coding

Source

Count: 3; Pubmed_search,Generif,UniProt

Literature support

Count: 5 PubMed records as below.

Evidence Status

Description

reviewed

Genomic characterization of the human mitochondrial tumor suppressor gene 1 (MTUS1): 5' cloning and preliminary analysis of the multiple gene promoters.

potential

Copy number variant in the candidate tumor suppressor gene MTUS1 and familial breast cancer risk.

potential

"Structural organization and expression of human MTUS1, a candidate 8p22 tumor suppressor gene encoding a family of angiotensin II AT2 receptor-interacting proteins, ATIP."

potential

Mutation analysis of the 8p22 candidate tumor suppressor gene ATIP/MTUS1 in hepatocellular carcinoma.

reviewed

"identified a tumor suppressor gene named MTSG1 at chromosome 8p21.3-22, encoding a mitochondrial protein, controlling cellular proliferation".
More detail of all 5 literatures about MTUS1

External Links

Links to Entrez Gene

57509

Links to all GeneRIF Items

57509

Links to iHOP

57509

Sequence Information

Nucleotide Sequence

>57509 : length: 3813
atgactgatgataattcagatgataaaatagaagatgaattgcaaaccttctttaccagt
gataaagatggaaatacacatgcatacaacccgaaatcaccacctacacaaaactcttca
gccagcagtgtgaactggaattctgccaacccagatgacatggtggttgattatgaaact
gaccctgctgtagttactggtgaaaatatttctttaagccttcagggtgttgaagtattt
ggtcatgaaaagtcttctagtgatttcattagtaagcaggtgttagatatgcataaagat
tctatttgtcagtgtcctgcacttgtaggtactgagaagcccaaatatctgcaacacagt
tgtcattccctagaagcagttgagggccagagtgttgagccatctttgccttttgtgtgg
aagcctaatgacaatttgaactgtgcaggctactgtgatgccttggagctaaaccaaaca
tttgacatgacagtggataaagttaactgcacctttatatcacatcatgccatcggaaag
agtcagtccttccatactgctggaagcctgccaccaactggtaggagaagtggaagtaca
tcttctttatcctattccacttggacatcttcccattctgataagacgcatgcaagagaa
actacttatgatagagaaagctttgaaaaccctcaagtcacaccatcagaagcccaagac
atgacttacacagcattttctgatgtggtgatgcaaagtgaggtttttgtttcagatatt
ggaaatcagtgtgcatgttcttcaggaaaggtcaccagtgagtacacagatggatcacaa
caaagactagttggagaaaaggagacacaagcactaacaccagtttctgatggcatggaa
gtccccaatgattctgcattacaagagttcttttgtttatcccatgatgaatccaatagc
gaaccacattcacagagctcatacaggcacaaggaaatgggccaaaatctgagagagaca
gtgtcctattgtcttattgatgatgaatgccctttaatggtgccagcttttgataagagc
gaagctcaagtgctgaacccagagcataaagtcactgagactgaagacacacaaatggtc
tccaaaggaaaggatttgggaacccaaaatcatacctcagaattgattctaagtagcccg
ccaggacaaaaggtgggctcgtcatttggactgacttgggatgcaaatgatatggtcatt
agcacagacaaaacgatgtgcatgtcaacaccagtcctagaacccacaaaagtaaccttt
tctgtttcaccgattgaagcgacggagaaatgtaagaaagtggagaagggtaatcgaggg
cttaaaaacataccagactcgaaggaggcacctgtgaacctgtgtaaacccagtttagga
aaatcaacaatcaaaacgaataccccaataggctgcaaagttagaaaaactgaaattata
agttacccaagaccaaacttcaagaatgtcaaagcaaaagttatgtctagagcagtgttg
cagcccaaagatgctgctttatcaaaggtcacgcccagacctcagcagaccagtgcctca
tcaccctcatcagtgaattcaagacaacaaacagtcttgagcagaacaccgagatctgac
ttgaatgcagacaaaaaagcagaaattctaattaacaagacacataagcagcagtttaat
aaactcattactagccaggctgtgcatgttacaactcattctaaaaatgcttcacacagg
gttccaagaacaacatctgccgtgaaatcgaatcaggaagatgttgacaaagccagttct
tctaactcagcatgcgagaccgggtccgtttctgcgttgtttcagaagatcaaaggcata
ctccctgttaaaatggaaagtgcagaatgtttggaaatgacctatgttcccaacattgat
aggattagccctgaaaagaagggtgaaaaagaaaatgggacatctatggaaaaacaagag
ctgaaacaagagattatgaatgagacttttgaatatggttctctgtttttgggctctgct
tcaaaaacaacgaccacctcaggtaggaatatatccaagcctgactcctgcggtttgagg
caaatagctgctccaaaagccaaagtggggccccctgtttcctgtttgaggcggaacagt
gacaatagaaatcccagtgctgatcgagccgtatctcctcagaggatcaggcgtgtgtcc
agttctggaaagcctacatccttgaaaactgcacagtcgtcatgggtgaatttgcctaga
ccacttcctaaatccaaagcatctttgaaaagtcctgcgctgcggaggacaggaagcacc
ccctcaatagccagcacccacagtgagctgagcacttacagcaacaattctggtaatgcc
gctgtcatcaaatatgaggagaaacctccaaaaccagcatttcagaatggttcctcagga
tccttttatttgaagcctttggtatccagggctcatgttcacttgatgaaaactcctcca
aaaggtccttcgagaaaaaatttatttacagctcttaatgcagttgaaaagagcaggcaa
aagaatcctcgaagcttatgtatccagccacagacagctcccgatgcgctgccccctgag
aaaacacttgaattgacgcaatataaaacaaaatgtgaaaaccaaagtggatttatcctg
cagctcaagcagcttcttgcctgtggtaataccaagtttgaggcattgacagttgtgatt
cagcacctgctgtctgagcgggaggaagcactgaaacaacacaaaaccctatctcaagaa
cttgttaacctccggggagagctagtcactgcttcaaccacctgtgagaaattagaaaaa
gccaggaatgagttacaaacagtgtatgaagcattcgtccagcagcaccaggctgaaaaa
acagaacgagagaatcggcttaaagagttttacaccagggagtatgaaaagcttcgggac
acttacattgaagaagcagagaagtacaaaatgcaattgcaagagcagtttgacaactta
aatgctgcgcatgaaacctctaagttggaaattgaagctagccactcagagaaacttgaa
ttgctaaagaaggcctatgaagcctccctttcagaaattaagaaaggccatgaaatagaa
aagaaatcgcttgaagatttactttctgagaagcaggaatcgctagagaagcaaatcaat
gatctgaagagtgaaaatgatgctttaaatgaaaaattgaaatcagaagaacaaaaaaga
agagcaagagaaaaagcaaatttgaaaaatcctcagatcatgtatctagaacaggagtta
gaaagcctgaaagctgtgttagagatcaagaatgagaaactgcatcaacaggacatcaag
ttaatgaaaatggagaaactggtggacaacaacacagcattggttgacaaattgaagcgt
ttccagcaggagaatgaagaattgaaagctcggatggacaagcacatggcaatctcaagg
cagctttccacggagcaggctgttctgcaagagtcgctggagaaggagtcgaaagtcaac
aagcgactctctatggaaaacgaggagcttctgtggaaactgcacaatggggacctgtgt
agccccaagagatcccccacatcctccgccatccctttgcagtcaccaaggaattcgggc
tccttccctagccccagcatttcacccagatga

Protein Sequence

>57509 : length: 1270
MTDDNSDDKIEDELQTFFTSDKDGNTHAYNPKSPPTQNSSASSVNWNSANPDDMVVDYET
DPAVVTGENISLSLQGVEVFGHEKSSSDFISKQVLDMHKDSICQCPALVGTEKPKYLQHS
CHSLEAVEGQSVEPSLPFVWKPNDNLNCAGYCDALELNQTFDMTVDKVNCTFISHHAIGK
SQSFHTAGSLPPTGRRSGSTSSLSYSTWTSSHSDKTHARETTYDRESFENPQVTPSEAQD
MTYTAFSDVVMQSEVFVSDIGNQCACSSGKVTSEYTDGSQQRLVGEKETQALTPVSDGME
VPNDSALQEFFCLSHDESNSEPHSQSSYRHKEMGQNLRETVSYCLIDDECPLMVPAFDKS
EAQVLNPEHKVTETEDTQMVSKGKDLGTQNHTSELILSSPPGQKVGSSFGLTWDANDMVI
STDKTMCMSTPVLEPTKVTFSVSPIEATEKCKKVEKGNRGLKNIPDSKEAPVNLCKPSLG
KSTIKTNTPIGCKVRKTEIISYPRPNFKNVKAKVMSRAVLQPKDAALSKVTPRPQQTSAS
SPSSVNSRQQTVLSRTPRSDLNADKKAEILINKTHKQQFNKLITSQAVHVTTHSKNASHR
VPRTTSAVKSNQEDVDKASSSNSACETGSVSALFQKIKGILPVKMESAECLEMTYVPNID
RISPEKKGEKENGTSMEKQELKQEIMNETFEYGSLFLGSASKTTTTSGRNISKPDSCGLR
QIAAPKAKVGPPVSCLRRNSDNRNPSADRAVSPQRIRRVSSSGKPTSLKTAQSSWVNLPR
PLPKSKASLKSPALRRTGSTPSIASTHSELSTYSNNSGNAAVIKYEEKPPKPAFQNGSSG
SFYLKPLVSRAHVHLMKTPPKGPSRKNLFTALNAVEKSRQKNPRSLCIQPQTAPDALPPE
KTLELTQYKTKCENQSGFILQLKQLLACGNTKFEALTVVIQHLLSEREEALKQHKTLSQE
LVNLRGELVTASTTCEKLEKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYEKLRD
TYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLKKAYEASLSEIKKGHEIE
KKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQEL
ESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQENEELKARMDKHMAISR
QLSTEQAVLQESLEKESKVNKRLSMENEELLWKLHNGDLCSPKRSPTSSAIPLQSPRNSG
SFPSPSISPR



Copyright © 2016-Present - The Univsersity of Texas Health Science Center at Houston Rights Reserved
Site Policies | State of Texas