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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 57531 |
Name | HACE1 |
Synonym | -;HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1;HACE1;HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 |
Definition | E3 ubiquitin-protein ligase HACE1|HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1 |
Position | 6q16.3 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
reviewed | "Deregulation of the tumor suppressor HACE1 is associated with natural killer/T-cell lymphoma, nasal type." |
reviewed | The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers. |
| More detail of all 2 literatures about HACE1 | |
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External Links |
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Links to Entrez Gene | 57531 |
Links to all GeneRIF Items | 57531 |
Links to iHOP | 57531 |
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Sequence Information |
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Nucleotide Sequence |
>57531 : length: 2730 atggagagagcgatggagcaactcaaccgcctgacgcgctcgctgcgccgcgcgcgcacc gtggagttgcccgaggataatgaaactgctgtttatacattaatgccaatggttatggct gatcaacacaggtctgtttctgaactactatcaaattcaaaatttgatgtcaattatgca ttcggacgtgtgaaaagaagcttgcttcacattgcagcaaattgtggatcggtggaatgc ttggttttgctgttaaagaaaggagcaaatcctaactatcaagatatttcaggctgtaca ccccttcatttggcagcaagaaatgggcagaagaaatgtatgagtaaattattagaatat agcgctgatgtcaacatttgtaataatgaaggccttacagcaatacattggctggctgtg aatgggcggacagaactactccatgaccttgtgcagcatgtcagtgatgttgatgttgag gatgccatggggcagacagcactgcatgttgcctgccagaacggtcacaagacgacagtg cagtgcttgctagacagtggtgctgatattaacaggccaaatgtatcaggagcaactcca ttgtactttgcttgcagtcatggtcagagagatacagcacagatcctactattacgagga gccaaatatctgccagataaaaatggagtaactcctctggatttatgtgtacagggtgga tatggagagacttgtgaagtattaattcaatatcacccgaggctttttcagactattatt caaatgacacagaatgaagacctccgagaaaacatgttacggcaagttctggagcatttg tctcagcaaagtgaaagccagtacctaaagattctaacaagccttgctgaagttgctaca acaaatggtcataaactgcttagcctctctagcaattatgatgctcaaatgaagagcctt ttaaggattgtgagaatgttttgtcacgtctttcgaattggtccatcctcccccagtaat ggaattgatatgggctacaatgggaataaaactccaagaagccaggtgttcaagcctctg gaattgctttggcactcgttagatgaatggctagttttaatagccacagaattgatgaaa aacaaaagagactcaacagagatcacttctattttactgaaacaaaaaggccaagatcaa gatgctgcttccattcctccatttgaacctccaggacctgggagctatgaaaatctgtcc actggcacaagggaatctaaaccagatgctcttgcagggagacaggaagccagtgcagat tgtcaggatgttatttctatgacagctaaccggctaagtgctgtcattcaagctttttac atgtgctgttcttgtcagatgcctccgggaatgacttcacctcgtttcattgaatttgtc tgcaaacatgatgaagttttaaaatgctttgttaatagaaatcccaaaattatatttgac cactttcactttctccttgaatgtcctgagttgatgtcaagattcatgcatatcataaaa gcacagccttttaaagatcgctgtgaatggttctatgaacatttgcattcaggacagcca gattcagatatggtgcacaggccagtgaatgaaaatgatatcctgctggttcacagagat tctatttttaggagtagctgtgaagttgtgtcaaaagcaaattgtgcaaagctaaagcaa gggattgctgtacggttccatggagaagaaggcatgggtcaaggtgttgtgcgtgagtgg tttgatattctgtccaatgagatagtcaatcctgattatgcattgtttacccagtcagct gatggaacaacttttcagcctaatagcaactcttatgtaaatcctgatcacttgaactat tttcggtttgctgggcagatcttgggattagcgttgaaccacaggcagctggtcaatatt tacttcacacgatccttctacaagcacattcttggtattcctgtaaattaccaagatgtg gcatccattgatccagaatatgcgaaaaatttgcaatggattttagataatgatataagt gatctgggtctagaactaactttttctgttgagactgatgtgtttggagcaatggaagag gtgcctttgaaacctgggggtgggagtattcttgtgacacaaaataataaagcggagtac gtccagcttgttactgaacttcgaatgacaagagccattcagcctcagatcaatgctttt ttacagggctttcatatgttcattccaccctccctcatacagctttttgatgaatatgaa ttggagctactgctttctggcatgccagaaattgatgtgagtgattggataaaaaataca gaatacacaagtggctatgaaagagaagatccagttattcagtggttctgggaagttgta gaagacattactcaagaggagagagttcttctcttacagtttgttacgggcagttccagg gtcccacatggtgggtttgctaatatcatgggtggaagtggattgcaaaactttacaatc gctgctgtgccatatactccaaatcttttaccaacttcaagcacatgcatcaacatgctc aagttacctgaatacccaagtaaagaaatactcaaggacagacttcttgtggcactacat tgtggcagctatggttacacaatggcataa |
Protein Sequence |
>57531 : length: 909 MERAMEQLNRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYA FGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEY SADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTV QCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGG YGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVAT TNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPL ELLWHSLDEWLVLIATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLS TGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFV CKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQP DSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREW FDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNI YFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEE VPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYE LELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSR VPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALH CGSYGYTMA |