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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 57575 |
Name | PCDH10 |
Synonym | OL-PCDH|PCDH19;protocadherin 10;PCDH10;protocadherin 10 |
Definition | ortholog of OL-pcdh|protocadherin-10 |
Position | 4q28.3 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
reviewed | PCDH10 is a gastric tumor suppressor; its methylation at early stages of gastric carcinogenesis is an independent prognostic factor. |
potential | "Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation." |
| More detail of all 2 literatures about PCDH10 | |
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Pathways and Diseases |
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Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Cadherin signaling pathway;PANTHER;P00012 |
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External Links |
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Links to Entrez Gene | 57575 |
Links to all GeneRIF Items | 57575 |
Links to iHOP | 57575 |
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Sequence Information |
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Nucleotide Sequence |
>57575 : length: 2691 atgattgtgctattattgtttgccttgctctggatggtggaaggagtcttttcccagctt cactacacggtacaggaggagcaggaacatggcactttcgtggggaatatcgctgaagat ctgggtctggacattacaaaactttcggctcgcgggtttcagacggtgcccaactcaagg accccttacttagacctcaacctggagacaggggtgctgtacgtgaacgagaaaatagac cgcgaacaaatctgcaaacagagcccctcctgtgtcctgcacctggaggtctttctggag aaccccctggagctgttccaggtggagatcgaggtgctggacattaatgacaaccccccc tctttcccggagccagacctgacggtggaaatctctgagagcgccacgccaggcactcgc ttccccttggagagcgcattcgacccagacgtgggcaccaactccttgcgcgactacgag atcacccccaacagctacttctccctggacgtgcagacccagggggatggcaaccgattc gctgagctggtgctggagaagccactggaccgagagcagcaagcggtgcaccgctacgtg ctgaccgcggtggacggaggaggtgggggaggagtaggagaaggagggggaggtggcggg ggagcaggcctgcccccccagcagcagcgcaccggcacggccctactcaccatccgagtg ctggactccaatgacaatgtgcccgctttcgaccaacccgtctacactgtgtccctacca gagaactctcccccaggcactctcgtgatccagctcaacgccaccgacccggacgagggc cagaacggtgaggtcgtgtactccttcagcagccacatttcgccccgggcgcgggagctt ttcggactctcgccgcgcactggcagactggaggtaagcggcgagttggactatgaagag agcccagtgtaccaagtgtacgtgcaagccaaggacctgggccccaacgccgtgcctgcg cactgcaaggtgctagtgcgagtactggatgctaatgacaacgcgccagagatcagcttc agcaccgtgaaggaagcggtgagtgagggcgcggcgcccggcactgtggtggcccttttc agcgtgactgaccgcgactcagaggagaatgggcaggtgcagtgcgagctactgggagac gtgcctttccgcctcaagtcttcctttaagaattactacaccatcgttaccgaagccccc ctggaccgagaggcgggggactcctacaccctgactgtagtggctcgggaccggggcgag cctgcgctctccaccagtaagtcgatccaggtacaagtgtcggatgtgaacgacaacgcg ccgcgtttcagccagccggtctacgacgtgtatgtgactgaaaacaacgtgcctggcgcc tacatctacgcggtgagcgccaccgaccgggatgagggcgccaacgcccagcttgcctac tctatcctcgagtgccagatccagggcatgagcgtcttcacctacgtttctatcaactct gagaacggctacttgtacgccctgcgctccttcgactatgagcagctgaaggacttcagt tttcaggtggaagcccgggacgctggcagcccccaggcgctggctggtaacgccactgtc aacatcctcatagtggatcaaaatgacaacgcccctgccatcgtggcgcctctaccaggg cgcaacgggactccagcgcgtgaggtgctgccccgctcggcggagccgggttacctgctc acccgcgtggccgccgtggacgcggacgacggcgagaacgcccggctcacttacagcatc gtgcgtggcaacgaaatgaacctctttcgcatggactggcgcaccggggagctgcgcaca gcacgccgagtcccggccaagcgcgacccccagcggccttatgagctggtgatcgaggtg cgcgaccatgggcagccgcccctttcctccaccgccaccctggtggttcagctggtggat ggcgccgtggagccccagggcgggggcgggagcggaggcggagggtcaggagagcaccag cgccccagtcgctctggcggcggggaaacctcgctagacctcaccctcatcctcatcatc gcgttgggctcggtgtccttcatcttcctgctggccatgatcgtgctggccgtgcgttgc caaaaagagaagaagctcaacatctatacttgtctggccagcgattgctgcctctgctgc tgctgctgcggtggcggaggttcgacctgctgtggccgccaagcccgggcgcgcaagaag aaactcagcaagtcagacatcatgctggtgcagagctccaatgtacccagtaacccggcc caggtgccgatagaggagtccgggggctttggctcccaccaccacaaccagaattactgc tatcaggtatgcctgacccctgagtccgccaagaccgacctgatgtttcttaagccctgc agcccttcgcggagtacggacactgagcacaacccctgcggggccatcgtcaccggttac accgaccagcagcctgatatcatctccaacggaagcattttgtccaacgaggtaaggctg aagcgaaaggaccaccatctctcatctcctccatcagaaagcctcctctag |
Protein Sequence |
>57575 : length: 896 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNEVRLKRKDHHLSSPPSESLL |