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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5909 |
Name | RAP1GAP |
Synonym | RAP1GA1|RAP1GAP1|RAP1GAPII|RAPGAP;RAP1 GTPase activating protein;RAP1GAP;RAP1 GTPase activating protein |
Definition | rap1 GTPase-activating protein 1 |
Position | 1p36.1-p35 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 3 PubMed records as below. |
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Evidence Status |
Description |
reviewed | The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma. |
potential | data identify rap1GAP as a putative tumor suppressor gene in pancreatic cancer. |
potential | Rap1GAP protein levels are tightly regulated and it may have a role as a tumor suppressor. |
| More detail of all 3 literatures about RAP1GAP | |
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Pathways and Diseases |
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Pathway | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway;PANTHER;P00027 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Disease | Pancreas cancer;FunDO |
Disease | plasma levels of liver enzymes;GAD |
Disease | Embryoma;FunDO |
Disease | Immunologic deficiency syndrome;FunDO |
Disease | METABOLIC;GAD |
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External Links |
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Links to Entrez Gene | 5909 |
Links to all GeneRIF Items | 5909 |
Links to iHOP | 5909 |
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Sequence Information |
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Nucleotide Sequence |
>5909 : length: 2046 atgattgagaagatgcagggaagcaggatggatgaacaacgctgctccttcccgccgccc ctcaaaacagaggaggactacattccatacccgagcgtgcacgaggtcttggggcgagaa ggacccttccccctcatcctgctgccccagtttgggggctactggattgagggcaccaac cacgaaatcaccagcatccccgagacagagccactgcagtcgcccacaaccaaggtgaag ctcgagtgcaaccccacagcccgcatctaccggaagcactttctcggcaaggagcatttc aattactactcactggacgctgccctcggccaccttgtcttctcactcaagtacgatgtc atcggggaccaagagcacctgcggctgctgctcaggaccaagtgccggacataccatgat gtcatccccatctcctgcctcaccgagttccctaatgttgtccagatggcaaagttggtg tgtgaagacgtcaatgtggatcggttctatcctgtgctctaccccaaggcttcccggctc atcgtcacctttgacgagcatgtcatcagcaataacttcaagtttggcgtcatttatcag aagcttgggcagacctccgaggaagaactcttcagcaccaatgaggaaagtcccgctttc gtggagttccttgaatttcttggccagaaggtcaaactgcaggactttaaggggttccga ggaggcctggacgtgacccacgggcagacggggaccgaatctgtgtactgcaacttccgc aacaaggagatcatgtttcacgtgtccaccaagctgccatacacggaaggggacgcccag cagttgcagcggaagcggcacatcgggaacgacatcgtggctgtggtcttccaggatgag aacactcctttcgtgcccgacatgatcgcgtccaacttcctgcatgcctacgtcgtggtg caggctgagggcgggggccctgatggccccctctacaaggtctctgtcactgcaagagat gatgtgcccttctttggaccccccctcccggaccccgctgtgttcaggaaggggcctgag ttccaggaatttttgctgacaaagctgatcaatgctgaatatgcctgctacaaggcagag aagtttgccaaactggaggagcggacgcgggccgccctcctggagacgctctatgaggaa ctacacatccacagccagtccatgatgggcttgggcggcgacgaggacaagatggagaat ggcagtgggggcggcggcttctttgagtctttcaagcgggtcatccggagccgcagccag tccatggatgccatggggctgagcaacaagaagcccaacaccgtgtccaccagccacagc gggagcttcgcgcccaacaaccccgacctggccaaggcggctggaatatcattgcttatt cctgggaaaagtgcgagtagattcggacgccggggcagtgccataggcataggaaccgtg gaagagtcactgattgtccctgggaagagccccacgaggaagaagtcgggcccgttcggc tcccgccgcagcagcgccattggcatcgagaacatacaggaggtgcaggagaagagggag agccctccggctggtcagaagaccccagacagcgggcacgtctcacaggagcccaagtcg gagaactcatccactcagagctccccagagatgcccacgaccaagaacagagcggagacc gcagcgcagagagcagaggcgctcaaggacttctcccgctcctcgtccagtgccagcagc ttcgccagcgtggtggaggagacggagggtgtggacggagaggacacaggcctggagagc gtgtcatcctcaggaacaccccacaagcgggactccttcatctatagcacgtggctggag gacagtgtcagcaccactagtgggggcagctccccagacgccggcaagttgggggaccct gcgtgtcccgagatcaagatccagctggaagcatctgagcagcacatgccccagctgggc tgttag |
Protein Sequence |
>5909 : length: 681 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPDAGKLGDP ACPEIKIQLEASEQHMPQLGC |