Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

5931

Name

RBBP7

Synonym

RbAp46;retinoblastoma binding protein 7;RBBP7;retinoblastoma binding protein 7

Definition

G1/S transition control protein-binding protein RbAp46|RBBP-7|histone acetyltransferase type B subunit 2|histone-binding protein RBBP7|nucleosome-remodeling factor subunit RBAP46|retinoblastoma-binding protein 7|retinoblastoma-binding protein RbAp46|retin

Position

Xp22.2

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

potential

"RT-PCR data show high expression of putative tumor suppressor genes Rsk4 and RbAp46 in 47% and 79% of breast carcinoma cases, respectively, whereas Cldn2 was down-regulated in 52% of breast cancer cases compared with normal adjacent tissues."
More detail of all 1 literatures about RBBP7

Pathways and Diseases

Pathway

Hedgehog signaling events mediated by Gli proteins;PID Curated;200147

Pathway

Regulation of Telomerase;PID Curated;200072

Pathway

Signaling events mediated by HDAC Class I;PID Curated;200070

Pathway

Regulation of nuclear SMAD2/3 signaling;PID Curated;200002

Pathway

mechanisms of transcriptional repression by dna methylation;PID BioCarta;100112

Pathway

Chromosome Maintenance;Reactome;REACT:22172

Pathway

the prc2 complex sets long-term gene silencing through modification of histone tails;PID BioCarta;100063

Disease

Breast cancer;FunDO

External Links

Links to Entrez Gene

5931

Links to all GeneRIF Items

5931

Links to iHOP

5931

Sequence Information

Nucleotide Sequence

>5931 : length: 1410
atggctgccgaggcgggcgtcgtgggagctggggcctcccctgatggggattggagagac
caggcctgtgggcttctgctacacgtgcatttgtcttcccgactgggtcgcgcagcccct
gtacgtacaggtcgtcatcttagaacagtgtttgaagatactgtggaggagcgtgtcatc
aatgaagaatataaaatctggaagaagaatacaccgtttctatatgacctggttatgacc
catgctcttcagtggcccagtcttaccgttcagtggcttcctgaagtgactaaacctgaa
ggaaaagattatgcccttcattggctagtgctggggactcatacgtctgatgagcagaat
catctggtggttgctcgagtacatattcccaatgatgatgcacagtttgatgcttcccat
tgtgacagtgacaagggtgaatttggtggctttggttctgtaacaggaaaaattgaatgt
gaaattaaaatcaatcacgaaggagaagtaaaccgtgctcgttacatgccgcagaatcct
cacatcattgctacaaaaacaccatcttctgatgtgttggtttttgactatacaaaacac
cctgctaaaccagacccaagtggagaatgtaatcctgatctcagattaagaggtcaccag
aaggaaggctatggtctctcctggaattcaaatttgagtggacatctcctaagtgcatct
gatgaccatactgtttgtctgtgggatataaacgcaggaccaaaagaaggcaaaattgtg
gatgctaaagccatctttactggccactcagctgttgtagaggatgtggcctggcacctg
ctgcacgagtcattgtttggatctgttgctgatgatcagaaacttatgatatgggacacc
aggtccaataccacctccaagccgagtcacttggtggatgcgcacactgccgaagtcaac
tgcctctcattcaatccctacagcgaatttattctagccaccggctctgcggataagacc
gtagctttatgggatctgcgtaacttaaaattaaaactccataccttcgaatctcataaa
gatgaaattttccaggtccactggtctccacataatgaaactattctggcttcaagtggt
actgaccgccgcctgaatgtgtgggatttaagtaaaattggggaagaacaatcagcagaa
gatgcagaagatgggcctccagaactcctgtttattcatggaggacacactgctaagatt
tcagattttagctggaaccccaatgagccttgggtcatttgctcagtgtctgaggataac
atcatgcagatatggcaaatggctgaaaatatttacaatgatgaagagtcagatgtcacg
acatccgaactggagggacaaggatcttaa

Protein Sequence

>5931 : length: 469
MAAEAGVVGAGASPDGDWRDQACGLLLHVHLSSRLGRAAPVRTGRHLRTVFEDTVEERVI
NEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQN
HLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNP
HIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSAS
DDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDT
RSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHK
DEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKI
SDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS



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