Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

64857

Name

PLEKHG2

Synonym

ARHGEF42|CLG;pleckstrin homology domain containing, family G (with RhoGef domain) member 2;PLEKHG2;pleckstrin homology domain containing, family G (with RhoGef domain) member 2

Definition

PH domain-containing family G member 2|common-site lymphoma/leukemia guanine nucleotide exchange factor|pleckstrin homology domain-containing family G member 2

Position

19q13.2

Gene Type

protein-coding

Source

Count: 1; UniProt

Literature support

Count: 0 PubMed records as below.

Evidence Status

Description

.
More detail of all 0 literatures about PLEKHG2

Pathways and Diseases

Pathway

Signaling by Rho GTPases;Reactome;REACT:11044

Pathway

Signaling by GPCR;Reactome;REACT:14797

Pathway

Signalling by NGF;Reactome;REACT:11061

Disease

Leukemia;FunDO

External Links

Links to Entrez Gene

64857

Links to all GeneRIF Items

64857

Links to iHOP

64857

Sequence Information

Nucleotide Sequence

>64857 : length: 4161
atgcctgagggagcccaaggactgagcctctccaaacctagcccaagcctcgggtgtggc
cgaagaggtgaagtgtgtgactgtggcaccgtgtgtgagactcggacagctcctgcagcc
cccaccatggcctccccccgaggttctgggagctccacatccctgagcacagtgggctct
gagggggatccagcccctgggcccactccagcctgctcagcctccaggccagagcccctt
ccagggcctcccatccgcctacatctctctccggtggggatcccaggttcagccagaccc
tcaaggctggagcgtgtggcccgggagatcgtggagacagaacgggcctatgtcagggac
ctccgcagcatcgtggaggactacctgggccctctgctggacggcggggtcctggggctg
agcgtggagcaggtgggcacgctgtttgccaacattgaggacatctacgagttcagcagc
gagctcctggaggacttggagaacagcagcagcgccgggggtattgccgagtgcttcgtg
cagaggagcgaggattttgacatctacacattgtactgcatgaactacccgagctccctg
gccctgctccgggagctgtcgttgtctccgccagcagccctgtggctgcaggagcgccag
gcccagcttcgccactcgctgcccctgcagagcttcctgctgaaacctgtccagcgcatt
ctcaagtaccatctgctgctgcaggaactagggaagcactgggcggagggcccaggcact
gggggtcgcgagatggtggaggaagctattgtgtccatgacagcggttgcctggtacatc
aacgacatgaagcgcaagcaggagcatgcagcgcgcctccaggaagtgcagcggcggctg
ggtggctggaccggaccagagctcagtgcttttggggaactggtgttggagggcgcgttc
cgaggaggcggagggggtggcccccggctacgagggggtgagcggctgctcttcctgttc
tctcggatgctgctggtggccaagcgcagggggctggagtacacctacaaaggccacatc
ttctgctgcaacctgagcgtgagcgagagtccccgagaccctctagggttcaaggtgtct
gatctgaccattcccaagcacagacacctgctccaggccaagaaccaagaagagaagagg
ctgtggattcactgtctccagcgcctcttctttgagaaccaccctgcctccatccctgcc
aaggcaaagcaagttctccttgaaaacagcctgcattgtgcccccaaaagtaagcctgtc
ctagagcccctgacacccccacttgggtctcctcgacctcgagatgctagaagttttacc
cctgggcgaaggaacacagctccatctcctgggccctctgtgattcgccgaggccgcagg
cagtctgagccggtgaaggacccttatgtcatgttcccacagaacgctaagcctggattc
aagcacgctggcagcgaaggggaactctaccctccagaatctcagccaccagtttcaggc
tctgcaccccctgaggacctggaggatgctggacccccaacactggacccctctgggacc
tcaatcactgaagaaatcctggaactgctgaatcagcgaggccttcgagatccagggccg
tccacccatgacattcccaagttccccggagactcccaggtgcctggcgacagcgaaacc
ctcacattccaagccctgcccagccgggactcttcagaagaggaggaggaggaagaggaa
gggctggagatggatgaacgggggccttccccactccacgtcctggaagggctcgaaagt
tccattgcagctgaaatgcccagcattccctgccttaccaaaattcctgacgtgcccaac
cttcctgaaattcccagccgctgtgaaattcccgaaggttctcgccttcctagtctctct
gacatttccgatgtttttgagatgccctgccttccagccatacctagtgtccccaacacc
cccagtctgtctagcactcccaccctctcctgtgactcctggctccaagggcctctgcag
gaaccagctgaggctccagccaccaggagagaactgttttctgggagcaatcctgggaaa
ctgggagagccgccttcaggaggcaaggcagggccagaggaggatgaagaaggggtatca
ttcacagacttccagccccaggatgtcacccaacatcagggattcccagatgagctggca
ttccgctcttgctcagaaatccggagcgcctggcaggcattggaacagggacagctggcc
cggccaggcttcccagagccactgctgatcctggaggattcggatctgggtggagacagc
gggagcgggaaggcaggagccccgagttcagaaaggacggcgtcccgagtgcgagagctg
gcccggctttacagcgagcggatccagcagatgcagcgggcggagactcgggcatcagcc
aatgccccgcgccgccggcctcgggttctggcccaaccccagccatccccctgtctgccc
caggagcaggcagagccagggctcctgcctgcctttggacacgtgctggtatgtgagctg
gccttcccactgacatgtgcccaggagtctgtccccctgggtcctgctgtctgggttcaa
gctgccatacctttgtcaaagcagggaggcagcccggatggccagggtctacatgtttcc
aatttgcctaagcaagaccttccgggcatccacgtttcagctgctacccttttgcctgag
caaggaggttcccggcatgtccaggctccagccgccacacctttgcccaagcaagaaggc
cccctgcacctccaggtgccggctcttacaactttctctgatcaaggccacccagaaatc
caagttccagccaccactcctttgcctgagcatagaagtcacatggttataccagctcca
tccaccgccttttgtcctgagcagggacactgtgcggacatccacgttcccaccactcca
gctttgcccaaggagatttgttctgatttcacagtttcagtcaccacccctgtgcccaag
caagaaggtcacctagacagcgagagcccaaccaatatcccactgacaaagcaaggaggt
tccagggatgttcagggcccagaccctgtctgcagtcaacccatccagcctttgtcttgg
catggaagcagcctggatccccagggcccaggcgacaccctaccacccttgccatgtcac
ctcccagaccttcagattccaggtacctcacctttgcctgcacatggaagccacctggac
catcggatcccagccaacgccccactgtctttgtcccaggagctcccagacactcaggtt
ccagctaccacacctttgcccctgccacaagtcctcacagacatctgggtccaagccctc
ccaacttcacccaagcagggaagcctcccagacatccagggtccagcggctgcacctcca
cttccggagccaagccttacagatacacaggtccaaaaactcacaccttcgttggagcag
aagagcctcatagatgcccatgttccagctgccacacctttacctgagagaggaggctct
ctagacattcagggcctctcacccaccccagttcagaccaccatggttttgtccaaacca
ggaggctccttagcctctcacgttgccaggttggagtcttcagacttgacgccacctcat
agtcccccaccttccagccgtcagctcctgggccccaatgcagctgccctctccagatac
ctggcagcctcatatatcagccagagcctggctcggcggcaggggcctgggggaggggcc
cccgcagcctcccggggctcctggtcctctgctcccacgtcacgggcatcttcgccgccc
ccccagccccagccaccacctcccccagccaggcggctcagctatgccacgacggttaac
atccacgtgggcgggggtgggcggctgcggccagccaaggcccaggtccggttgaaccac
cctgctctcttggcctccacacaggaatctatgggccttcacagggcccagggggctcct
gatgcccccttccacatgtga

Protein Sequence

>64857 : length: 1386
MPEGAQGLSLSKPSPSLGCGRRGEVCDCGTVCETRTAPAAPTMASPRGSGSSTSLSTVGS
EGDPAPGPTPACSASRPEPLPGPPIRLHLSPVGIPGSARPSRLERVAREIVETERAYVRD
LRSIVEDYLGPLLDGGVLGLSVEQVGTLFANIEDIYEFSSELLEDLENSSSAGGIAECFV
QRSEDFDIYTLYCMNYPSSLALLRELSLSPPAALWLQERQAQLRHSLPLQSFLLKPVQRI
LKYHLLLQELGKHWAEGPGTGGREMVEEAIVSMTAVAWYINDMKRKQEHAARLQEVQRRL
GGWTGPELSAFGELVLEGAFRGGGGGGPRLRGGERLLFLFSRMLLVAKRRGLEYTYKGHI
FCCNLSVSESPRDPLGFKVSDLTIPKHRHLLQAKNQEEKRLWIHCLQRLFFENHPASIPA
KAKQVLLENSLHCAPKSKPVLEPLTPPLGSPRPRDARSFTPGRRNTAPSPGPSVIRRGRR
QSEPVKDPYVMFPQNAKPGFKHAGSEGELYPPESQPPVSGSAPPEDLEDAGPPTLDPSGT
SITEEILELLNQRGLRDPGPSTHDIPKFPGDSQVPGDSETLTFQALPSRDSSEEEEEEEE
GLEMDERGPSPLHVLEGLESSIAAEMPSIPCLTKIPDVPNLPEIPSRCEIPEGSRLPSLS
DISDVFEMPCLPAIPSVPNTPSLSSTPTLSCDSWLQGPLQEPAEAPATRRELFSGSNPGK
LGEPPSGGKAGPEEDEEGVSFTDFQPQDVTQHQGFPDELAFRSCSEIRSAWQALEQGQLA
RPGFPEPLLILEDSDLGGDSGSGKAGAPSSERTASRVRELARLYSERIQQMQRAETRASA
NAPRRRPRVLAQPQPSPCLPQEQAEPGLLPAFGHVLVCELAFPLTCAQESVPLGPAVWVQ
AAIPLSKQGGSPDGQGLHVSNLPKQDLPGIHVSAATLLPEQGGSRHVQAPAATPLPKQEG
PLHLQVPALTTFSDQGHPEIQVPATTPLPEHRSHMVIPAPSTAFCPEQGHCADIHVPTTP
ALPKEICSDFTVSVTTPVPKQEGHLDSESPTNIPLTKQGGSRDVQGPDPVCSQPIQPLSW
HGSSLDPQGPGDTLPPLPCHLPDLQIPGTSPLPAHGSHLDHRIPANAPLSLSQELPDTQV
PATTPLPLPQVLTDIWVQALPTSPKQGSLPDIQGPAAAPPLPEPSLTDTQVQKLTPSLEQ
KSLIDAHVPAATPLPERGGSLDIQGLSPTPVQTTMVLSKPGGSLASHVARLESSDLTPPH
SPPPSSRQLLGPNAAALSRYLAASYISQSLARRQGPGGGAPAASRGSWSSAPTSRASSPP
PQPQPPPPPARRLSYATTVNIHVGGGGRLRPAKAQVRLNHPALLASTQESMGLHRAQGAP
DAPFHM



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