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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 64857 |
Name | PLEKHG2 |
Synonym | ARHGEF42|CLG;pleckstrin homology domain containing, family G (with RhoGef domain) member 2;PLEKHG2;pleckstrin homology domain containing, family G (with RhoGef domain) member 2 |
Definition | PH domain-containing family G member 2|common-site lymphoma/leukemia guanine nucleotide exchange factor|pleckstrin homology domain-containing family G member 2 |
Position | 19q13.2 |
Gene Type | protein-coding |
Source | Count: 1; UniProt |
Literature support | Count: 0 PubMed records as below. |
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Evidence Status |
Description |
| . |
| More detail of all 0 literatures about PLEKHG2 | |
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Pathways and Diseases |
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Pathway | Signaling by Rho GTPases;Reactome;REACT:11044 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Disease | Leukemia;FunDO |
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External Links |
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Links to Entrez Gene | 64857 |
Links to all GeneRIF Items | 64857 |
Links to iHOP | 64857 |
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Sequence Information |
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Nucleotide Sequence |
>64857 : length: 4161 atgcctgagggagcccaaggactgagcctctccaaacctagcccaagcctcgggtgtggc cgaagaggtgaagtgtgtgactgtggcaccgtgtgtgagactcggacagctcctgcagcc cccaccatggcctccccccgaggttctgggagctccacatccctgagcacagtgggctct gagggggatccagcccctgggcccactccagcctgctcagcctccaggccagagcccctt ccagggcctcccatccgcctacatctctctccggtggggatcccaggttcagccagaccc tcaaggctggagcgtgtggcccgggagatcgtggagacagaacgggcctatgtcagggac ctccgcagcatcgtggaggactacctgggccctctgctggacggcggggtcctggggctg agcgtggagcaggtgggcacgctgtttgccaacattgaggacatctacgagttcagcagc gagctcctggaggacttggagaacagcagcagcgccgggggtattgccgagtgcttcgtg cagaggagcgaggattttgacatctacacattgtactgcatgaactacccgagctccctg gccctgctccgggagctgtcgttgtctccgccagcagccctgtggctgcaggagcgccag gcccagcttcgccactcgctgcccctgcagagcttcctgctgaaacctgtccagcgcatt ctcaagtaccatctgctgctgcaggaactagggaagcactgggcggagggcccaggcact gggggtcgcgagatggtggaggaagctattgtgtccatgacagcggttgcctggtacatc aacgacatgaagcgcaagcaggagcatgcagcgcgcctccaggaagtgcagcggcggctg ggtggctggaccggaccagagctcagtgcttttggggaactggtgttggagggcgcgttc cgaggaggcggagggggtggcccccggctacgagggggtgagcggctgctcttcctgttc tctcggatgctgctggtggccaagcgcagggggctggagtacacctacaaaggccacatc ttctgctgcaacctgagcgtgagcgagagtccccgagaccctctagggttcaaggtgtct gatctgaccattcccaagcacagacacctgctccaggccaagaaccaagaagagaagagg ctgtggattcactgtctccagcgcctcttctttgagaaccaccctgcctccatccctgcc aaggcaaagcaagttctccttgaaaacagcctgcattgtgcccccaaaagtaagcctgtc ctagagcccctgacacccccacttgggtctcctcgacctcgagatgctagaagttttacc cctgggcgaaggaacacagctccatctcctgggccctctgtgattcgccgaggccgcagg cagtctgagccggtgaaggacccttatgtcatgttcccacagaacgctaagcctggattc aagcacgctggcagcgaaggggaactctaccctccagaatctcagccaccagtttcaggc tctgcaccccctgaggacctggaggatgctggacccccaacactggacccctctgggacc tcaatcactgaagaaatcctggaactgctgaatcagcgaggccttcgagatccagggccg tccacccatgacattcccaagttccccggagactcccaggtgcctggcgacagcgaaacc ctcacattccaagccctgcccagccgggactcttcagaagaggaggaggaggaagaggaa gggctggagatggatgaacgggggccttccccactccacgtcctggaagggctcgaaagt tccattgcagctgaaatgcccagcattccctgccttaccaaaattcctgacgtgcccaac cttcctgaaattcccagccgctgtgaaattcccgaaggttctcgccttcctagtctctct gacatttccgatgtttttgagatgccctgccttccagccatacctagtgtccccaacacc cccagtctgtctagcactcccaccctctcctgtgactcctggctccaagggcctctgcag gaaccagctgaggctccagccaccaggagagaactgttttctgggagcaatcctgggaaa ctgggagagccgccttcaggaggcaaggcagggccagaggaggatgaagaaggggtatca ttcacagacttccagccccaggatgtcacccaacatcagggattcccagatgagctggca ttccgctcttgctcagaaatccggagcgcctggcaggcattggaacagggacagctggcc cggccaggcttcccagagccactgctgatcctggaggattcggatctgggtggagacagc gggagcgggaaggcaggagccccgagttcagaaaggacggcgtcccgagtgcgagagctg gcccggctttacagcgagcggatccagcagatgcagcgggcggagactcgggcatcagcc aatgccccgcgccgccggcctcgggttctggcccaaccccagccatccccctgtctgccc caggagcaggcagagccagggctcctgcctgcctttggacacgtgctggtatgtgagctg gccttcccactgacatgtgcccaggagtctgtccccctgggtcctgctgtctgggttcaa gctgccatacctttgtcaaagcagggaggcagcccggatggccagggtctacatgtttcc aatttgcctaagcaagaccttccgggcatccacgtttcagctgctacccttttgcctgag caaggaggttcccggcatgtccaggctccagccgccacacctttgcccaagcaagaaggc cccctgcacctccaggtgccggctcttacaactttctctgatcaaggccacccagaaatc caagttccagccaccactcctttgcctgagcatagaagtcacatggttataccagctcca tccaccgccttttgtcctgagcagggacactgtgcggacatccacgttcccaccactcca gctttgcccaaggagatttgttctgatttcacagtttcagtcaccacccctgtgcccaag caagaaggtcacctagacagcgagagcccaaccaatatcccactgacaaagcaaggaggt tccagggatgttcagggcccagaccctgtctgcagtcaacccatccagcctttgtcttgg catggaagcagcctggatccccagggcccaggcgacaccctaccacccttgccatgtcac ctcccagaccttcagattccaggtacctcacctttgcctgcacatggaagccacctggac catcggatcccagccaacgccccactgtctttgtcccaggagctcccagacactcaggtt ccagctaccacacctttgcccctgccacaagtcctcacagacatctgggtccaagccctc ccaacttcacccaagcagggaagcctcccagacatccagggtccagcggctgcacctcca cttccggagccaagccttacagatacacaggtccaaaaactcacaccttcgttggagcag aagagcctcatagatgcccatgttccagctgccacacctttacctgagagaggaggctct ctagacattcagggcctctcacccaccccagttcagaccaccatggttttgtccaaacca ggaggctccttagcctctcacgttgccaggttggagtcttcagacttgacgccacctcat agtcccccaccttccagccgtcagctcctgggccccaatgcagctgccctctccagatac ctggcagcctcatatatcagccagagcctggctcggcggcaggggcctgggggaggggcc cccgcagcctcccggggctcctggtcctctgctcccacgtcacgggcatcttcgccgccc ccccagccccagccaccacctcccccagccaggcggctcagctatgccacgacggttaac atccacgtgggcgggggtgggcggctgcggccagccaaggcccaggtccggttgaaccac cctgctctcttggcctccacacaggaatctatgggccttcacagggcccagggggctcct gatgcccccttccacatgtga |
Protein Sequence |
>64857 : length: 1386 MPEGAQGLSLSKPSPSLGCGRRGEVCDCGTVCETRTAPAAPTMASPRGSGSSTSLSTVGS EGDPAPGPTPACSASRPEPLPGPPIRLHLSPVGIPGSARPSRLERVAREIVETERAYVRD LRSIVEDYLGPLLDGGVLGLSVEQVGTLFANIEDIYEFSSELLEDLENSSSAGGIAECFV QRSEDFDIYTLYCMNYPSSLALLRELSLSPPAALWLQERQAQLRHSLPLQSFLLKPVQRI LKYHLLLQELGKHWAEGPGTGGREMVEEAIVSMTAVAWYINDMKRKQEHAARLQEVQRRL GGWTGPELSAFGELVLEGAFRGGGGGGPRLRGGERLLFLFSRMLLVAKRRGLEYTYKGHI FCCNLSVSESPRDPLGFKVSDLTIPKHRHLLQAKNQEEKRLWIHCLQRLFFENHPASIPA KAKQVLLENSLHCAPKSKPVLEPLTPPLGSPRPRDARSFTPGRRNTAPSPGPSVIRRGRR QSEPVKDPYVMFPQNAKPGFKHAGSEGELYPPESQPPVSGSAPPEDLEDAGPPTLDPSGT SITEEILELLNQRGLRDPGPSTHDIPKFPGDSQVPGDSETLTFQALPSRDSSEEEEEEEE GLEMDERGPSPLHVLEGLESSIAAEMPSIPCLTKIPDVPNLPEIPSRCEIPEGSRLPSLS DISDVFEMPCLPAIPSVPNTPSLSSTPTLSCDSWLQGPLQEPAEAPATRRELFSGSNPGK LGEPPSGGKAGPEEDEEGVSFTDFQPQDVTQHQGFPDELAFRSCSEIRSAWQALEQGQLA RPGFPEPLLILEDSDLGGDSGSGKAGAPSSERTASRVRELARLYSERIQQMQRAETRASA NAPRRRPRVLAQPQPSPCLPQEQAEPGLLPAFGHVLVCELAFPLTCAQESVPLGPAVWVQ AAIPLSKQGGSPDGQGLHVSNLPKQDLPGIHVSAATLLPEQGGSRHVQAPAATPLPKQEG PLHLQVPALTTFSDQGHPEIQVPATTPLPEHRSHMVIPAPSTAFCPEQGHCADIHVPTTP ALPKEICSDFTVSVTTPVPKQEGHLDSESPTNIPLTKQGGSRDVQGPDPVCSQPIQPLSW HGSSLDPQGPGDTLPPLPCHLPDLQIPGTSPLPAHGSHLDHRIPANAPLSLSQELPDTQV PATTPLPLPQVLTDIWVQALPTSPKQGSLPDIQGPAAAPPLPEPSLTDTQVQKLTPSLEQ KSLIDAHVPAATPLPERGGSLDIQGLSPTPVQTTMVLSKPGGSLASHVARLESSDLTPPH SPPPSSRQLLGPNAAALSRYLAASYISQSLARRQGPGGGAPAASRGSWSSAPTSRASSPP PQPQPPPPPARRLSYATTVNIHVGGGGRLRPAKAQVRLNHPALLASTQESMGLHRAQGAP DAPFHM |