|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 6596 |
Name | HLTF |
Synonym | HIP116|HIP116A|HLTF1|RNF80|SMARCA3|SNF2L3|ZBU1;helicase-like transcription factor;HLTF;helicase-like transcription factor |
Definition | DNA-binding protein/plasminogen activator inhibitor 1 regulator|DNA-binding protein/plasminogen activator inhibitor-1 regulator|RING finger protein 80|SNF2-like 3|SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, mem |
Position | 3q25.1-q26.1 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
|
Evidence Status |
Description |
potential | "HLTF can promote error-free replication of damaged DNA and support a role for HLTF in preventing mutagenesis and carcinogenesis, providing thereby for its potential tumor suppressor role." |
| More detail of all 1 literatures about HLTF | |
|
Pathways and Diseases |
|
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Disease | Nevus;FunDO |
Disease | Renal Cell cancer;FunDO |
Disease | Stomach cancer;FunDO |
Disease | Esophagus cancer;FunDO |
Disease | Colon cancer;FunDO |
|
External Links |
|
Links to Entrez Gene | 6596 |
Links to all GeneRIF Items | 6596 |
Links to iHOP | 6596 |
|
Sequence Information |
|
Nucleotide Sequence |
>6596 : length: 3030 atgtcctggatgttcaagagggatccagtttggaagtacttgcagactgtccagtatgga gttcatggaaattttccacgcctctcatatccaactttctttccacgttttgaattccaa gatgttatccctccagatgactttctaactagtgatgaagaagtagattccgttttattt ggaagtttgagaggtcatgtggttggactacgctattacacgggagtagttaataataat gaaatggttgcattacaacgagatcctaataacccttatgataagaatgcaattaaagta aacaatgtgaatggaaatcaagttggccatttaaagaaagagcttgcaggtgctttggcc tatatcatggacaacaaattggcacaaattgaaggggtagttccttttggtgcaaacaat gcttttaccatgcctctgcatatgactttttggggaaaagaagaaaatagaaaagcggtt tcagatcagttgaagaaacatggatttaaattgggtcctgcaccaaaaactttaggattc aatttggaaagtggttggggctctggaagagctggaccaagctatagtatgccagtgcat gctgcagtacagatgacaactgaacagcttaaaacagaatttgacaaattgtttgaagat ttaaaagaagatgataaaacccatgaaatggaaccagctgaggctattgaaacaccactg cttccacatcaaaaacaagctctagcttggatggtgtcacgggaaaatagcaaagaactt ccaccattctgggaacagcgaaatgacttatactataacacaataacaaatttttctgag aaggaccgaccagaaaatgtccatggaggaattttagctgatgatatgggtttgggtaaa actcttacggccattgcagtaatccttaccaacttccatgatggcagacctcttcctatt gaaagagttaaaaagaatctactgaagaaggaatataatgttaacgatgactctatgaaa cttggaggaaacaataccagtgaaaaggcagatggactaagcaaagacgcatctagatgt agtgaacaacccagtatttcagatatcaaggagaagagtaagtttcgcatgtcagaattg tctagctcccgccccaaaagaagaaaaactgctgtccagtacatagaaagcagtgattca gaggaaattgaaacaagtgaattgccgcagaaaatgaaaggcaaactgaaaaatgtacag tctgaaactaaaggcagggcgaaagcaggatcttctaaggttatagaagatgtggcattt gcatgtgcattaacttcatctgttcctacaacaaaaaagaaaatgttgaaaaagggagct tgtgcagtggaggggtcaaagaaaactgatgttgaggagagaccaagaacaacactgatc atctgtccgctttctgtgttaagcaactggattgaccagtttggacaacatataaaatca gatgtacacttgaatttttatgtttattatggtcctgatcgtattagagaaccggcctta ctttcaaaacaggatattgttttgactacgtataatattttaactcatgactatggaact aaaggagatagtccattacatagcataaggtggctaagagtgatcctggatgaaggacat gccatacgaaatccaaatgctcagcagacaaaagctgtacttgacttagaatcagaaaga agatgggttttgacaggtactccaatccagaattctttaaaggacttgtggtctcttctt tcctttttaaaacttaaaccatttattgatagagaatggtggcatagaacaatacagcgt cctgtcacaatgggagatgaaggaggacttaggcgtttacagtccctaattaaaaatatt acacttagaagaacaaagacaagcaaaattaaaggaaaacctgttttggagttaccagaa cgtaaagtatttattcagcacattacactttcagatgaagagagaaagatttatcagtct gtgaaaaatgaaggcagagccactattggaaggtattttaatgaagggactgtcctggca cattatgcagatgtcctgggtcttttgcttagactgcggcaaatttgttgccatacttac cttcttacaaatgcagtgtcttccaatggcccctcaggaaatgatacacctgaagaactg agaaagaagttaataaggaagatgaagttaattctgagctcaggttcagatgaggaatgt gcaatttgcctggattctttaacagttcctgtgataacacattgtgcacatgtattttgt aaaccctgtatttgccaagtcattcagaatgagcagccacatgctaaatgccctttatgc agaaatgatatacatgaagataatttattagaatgtcctccagaagaattagcacgtgac agtgagaaaaagtctgatatggaatggacatccagttcaaagattaatgcgctaatgcac gcattgactgacttaagaaagaagaatcccaacataaaaagtttggttgtttctcagttt acaacattcctgtctttaatagaaataccacttaaagcctctggatttgtgtttactcgt ttggatggttccatggcccaaaagaaaagagttgaatcaattcagtgttttcaaaacact gaagcaggatctccaactataatgcttctgtccttaaaagcaggtggagttggtttgaat ctgtctgcagcttctcgagtgtttttaatggatccagcctggaatcctgctgctgaagat cagtgctttgacagatgccatagacttggtcagaagcaagaagttatcatcacaaaattc attgtaaaggactctgttgaagaaaatatgctgaaaatacaaaacaaaaagagagaactt gcagcaggagcctttggaactaaaaaaccaaatgctgacgaaatgaaacaagccaaaatt aatgaaatcagaacattaattgacttataa |
Protein Sequence |
>6596 : length: 1009 MSWMFKRDPVWKYLQTVQYGVHGNFPRLSYPTFFPRFEFQDVIPPDDFLTSDEEVDSVLF GSLRGHVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNNVNGNQVGHLKKELAGALA YIMDNKLAQIEGVVPFGANNAFTMPLHMTFWGKEENRKAVSDQLKKHGFKLGPAPKTLGF NLESGWGSGRAGPSYSMPVHAAVQMTTEQLKTEFDKLFEDLKEDDKTHEMEPAEAIETPL LPHQKQALAWMVSRENSKELPPFWEQRNDLYYNTITNFSEKDRPENVHGGILADDMGLGK TLTAIAVILTNFHDGRPLPIERVKKNLLKKEYNVNDDSMKLGGNNTSEKADGLSKDASRC SEQPSISDIKEKSKFRMSELSSSRPKRRKTAVQYIESSDSEEIETSELPQKMKGKLKNVQ SETKGRAKAGSSKVIEDVAFACALTSSVPTTKKKMLKKGACAVEGSKKTDVEERPRTTLI ICPLSVLSNWIDQFGQHIKSDVHLNFYVYYGPDRIREPALLSKQDIVLTTYNILTHDYGT KGDSPLHSIRWLRVILDEGHAIRNPNAQQTKAVLDLESERRWVLTGTPIQNSLKDLWSLL SFLKLKPFIDREWWHRTIQRPVTMGDEGGLRRLQSLIKNITLRRTKTSKIKGKPVLELPE RKVFIQHITLSDEERKIYQSVKNEGRATIGRYFNEGTVLAHYADVLGLLLRLRQICCHTY LLTNAVSSNGPSGNDTPEELRKKLIRKMKLILSSGSDEECAICLDSLTVPVITHCAHVFC KPCICQVIQNEQPHAKCPLCRNDIHEDNLLECPPEELARDSEKKSDMEWTSSSKINALMH ALTDLRKKNPNIKSLVVSQFTTFLSLIEIPLKASGFVFTRLDGSMAQKKRVESIQCFQNT EAGSPTIMLLSLKAGGVGLNLSAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKF IVKDSVEENMLKIQNKKRELAAGAFGTKKPNADEMKQAKINEIRTLIDL |