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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 6608 |
Name | SMO |
Synonym | FZD11|Gx|SMOH;smoothened, frizzled family receptor;SMO;smoothened, frizzled family receptor |
Definition | frizzled family member 11|protein Gx|seven transmembrane helix receptor|smoothened homolog|smoothened, seven transmembrane spanning receptor |
Position | 7q32.3 |
Gene Type | protein-coding |
Source | Count: 1; TAG |
Literature support | Count: 0 PubMed records as below. |
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Evidence Status |
Description |
| . |
| More detail of all 0 literatures about SMO | |
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Pathways and Diseases |
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Pathway | Hedgehog signaling events mediated by Gli proteins;PID Curated;200147 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Hedgehog signaling pathway;PANTHER;P00025 |
Pathway | Signaling events mediated by the Hedgehog family;PID Curated;200144 |
Pathway | Basal cell carcinoma;KEGG PATHWAY;hsa05217 |
Pathway | Hedgehog signaling pathway;KEGG PATHWAY;hsa04340 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Class B/2 (Secretin family receptors);PID Reactome;500428 |
Disease | Basal cell carcinoma, somatic;OMIM |
Disease | Hyperglycemia;FunDO |
Disease | Cancers;KEGG DISEASE |
Disease | Bone disease;FunDO |
Disease | Chondrosarcoma;FunDO |
Disease | Basal cell carcinoma;KEGG DISEASE;H00039 |
Disease | Skin cancer;FunDO |
Disease | Pancreas cancer;FunDO |
Disease | Skin cancers;KEGG DISEASE |
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External Links |
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Links to Entrez Gene | 6608 |
Links to all GeneRIF Items | 6608 |
Links to iHOP | 6608 |
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Sequence Information |
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Nucleotide Sequence |
>6608 : length: 2364 atggccgctgcccgcccagcgcgggggccggagctcccgctcctggggctgctgctgctg ctgctgctgggggacccgggccggggggcggcctcgagcgggaacgcgaccgggcctggg cctcggagcgcgggcgggagcgcgaggaggagcgcggcggtgactggccctccgccgccg ctgagccactgcggccgggctgccccctgcgagccgctgcgctacaacgtgtgcctgggc tcggtgctgccctacggggccacctccacactgctggccggagactcggactcccaggag gaagcgcacggcaagctcgtgctctggtcgggcctccggaatgccccccgctgctgggca gtgatccagcccctgctgtgtgccgtatacatgcccaagtgtgagaatgaccgggtggag ctgcccagccgtaccctctgccaggccacccgaggcccctgtgccatcgtggagagggag cggggctggcctgacttcctgcgctgcactcctgaccgcttccctgaaggctgcacgaat gaggtgcagaacatcaagttcaacagttcaggccagtgcgaagtgcccttggttcggaca gacaaccccaagagctggtacgaggacgtggagggctgcggcatccagtgccagaacccg ctcttcacagaggctgagcaccaggacatgcacagctacatcgcggccttcggggccgtc acgggcctctgcacgctcttcaccctggccacattcgtggctgactggcggaactcgaat cgctaccctgctgttattctcttctacgtcaatgcgtgcttctttgtgggcagcattggc tggctggcccagttcatggatggtgcccgccgagagatcgtctgccgtgcagatggcacc atgaggcttggggagcccacctccaatgagactctgtcctgcgtcatcatctttgtcatc gtgtactacgccctgatggctggtgtggtttggtttgtggtcctcacctatgcctggcac acttccttcaaagccctgggcaccacctaccagcctctctcgggcaagacctcctacttc cacctgctcacctggtcactcccctttgtcctcactgtggcaatccttgctgtggcgcag gtggatggggactctgtgagtgggatttgttttgtgggctacaagaactaccgataccgt gcgggcttcgtgctggccccaatcggcctggtgctcatcgtgggaggctacttcctcatc cgaggagtcatgactctgttctccatcaagagcaaccaccccgggctgctgagtgagaag gctgccagcaagatcaacgagaccatgctgcgcctgggcatttttggcttcctggccttt ggctttgtgctcattaccttcagctgccacttctacgacttcttcaaccaggctgagtgg gagcgcagcttccgggactatgtgctatgtcaggccaatgtgaccatcgggctgcccacc aagcagcccatccctgactgtgagatcaagaatcgcccgagccttctggtggagaagatc aacctgtttgccatgtttggaactggcatcgccatgagcacctgggtctggaccaaggcc acgctgctcatctggaggcgtacctggtgcaggttgactgggcagagtgacgatgagcca aagcggatcaagaagagcaagatgattgccaaggccttctctaagcggcacgagctcctg cagaacccaggccaggagctgtccttcagcatgcacactgtgtcccacgacgggcccgtg gcgggcttggcctttgacctcaatgagccctcagctgatgtctcctctgcctgggcccag catgtcaccaagatggtggctcggagaggagccatactgccccaggatatttctgtcacc cctgtggcaactccagtgcccccagaggaacaagccaacctgtggctggttgaggcagag atctccccagagctgcagaagcgcctgggccggaagaagaagaggaggaagaggaagaag gaggtgtgcccgctggcgccgccccctgagcttcacccccctgcccctgcccccagtacc attcctcgactgcctcagctgccccggcagaaatgcctggtggctgcaggtgcctgggga gctggggactcttgccgacagggagcgtggaccctggtctccaacccattctgcccagag cccagtccccctcaggatccatttctgcccagtgcaccggcccccgtggcatgggctcat ggccgccgacagggcctggggcctattcactcccgcaccaacctgatggacacagaactc atggatgcagactcggacttctga |
Protein Sequence |
>6608 : length: 787 MAAARPARGPELPLLGLLLLLLLGDPGRGAASSGNATGPGPRSAGGSARRSAAVTGPPPP LSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWA VIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTN EVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAV TGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGT MRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYF HLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLI RGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEW ERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKA TLLIWRRTWCRLTGQSDDEPKRIKKSKMIAKAFSKRHELLQNPGQELSFSMHTVSHDGPV AGLAFDLNEPSADVSSAWAQHVTKMVARRGAILPQDISVTPVATPVPPEEQANLWLVEAE ISPELQKRLGRKKKRRKRKKEVCPLAPPPELHPPAPAPSTIPRLPQLPRQKCLVAAGAWG AGDSCRQGAWTLVSNPFCPEPSPPQDPFLPSAPAPVAWAHGRRQGLGPIHSRTNLMDTEL MDADSDF |