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| General information | Expression | Regulation | Mutation | Interaction | 
| Basic Information | |
|---|---|
| Gene ID | 6648 | 
| Name | SOD2 | 
| Synonym | IPOB|MNSOD|MVCD6;superoxide dismutase 2, mitochondrial;SOD2;superoxide dismutase 2, mitochondrial | 
| Definition | Mn superoxide dismutase|indophenoloxidase B|manganese-containing superoxide dismutase|mangano-superoxide dismutase|superoxide dismutase [Mn], mitochondrial | 
| Position | 6q25.3 | 
| Gene Type | protein-coding | 
| Source | Count: 1; Generif | 
| Literature support | Count: 1 PubMed records as below. | 
| Evidence Status | Description | 
| potential | MnSOD may be a tumor suppressor gene in human pancreatic cancer. | 
| potential | MnSOD may be a tumor suppressor gene in pancreatic cancer. | 
| More detail of all 1 literatures about SOD2 | |
| Pathways and Diseases | |
| Pathway | erythropoietin mediated neuroprotection through nf-kb;PID BioCarta;100176 | 
| Pathway | Huntington's disease;KEGG PATHWAY;hsa05016 | 
| Pathway | superoxide radicals degradation;BioCyc;DETOX1-PWY | 
| Pathway | FoxO family signaling;PID Curated;200091 | 
| Pathway | Peroxisome;KEGG PATHWAY;hsa04146 | 
| Disease | Lupus erythematosus;FunDO | 
| Disease | cirrhosis, alcoholic;GAD | 
| Disease | IMMUNE;GAD | 
| Disease | Prostatic Neoplasms;GAD | 
| Disease | Albuminuria;GAD | 
| Disease | radiotherapy response;GAD | 
| Disease | Alzheimer's disease;GAD | 
| Disease | breast cancer;GAD | 
| Disease | carotid atherosclerosis;GAD | 
| Disease | Asthma;FunDO | 
| Disease | diabetes, type 2;GAD | 
| Disease | Cancer;FunDO | 
| Disease | Microvascular complications of diabetes, susceptibility to, 6;OMIM | 
| Disease | bladder cancer;GAD | 
| Disease | HIV infection;FunDO | 
| Disease | Glaucoma;FunDO | 
| Disease | Skin cancer;FunDO | 
| Disease | AGING;GAD | 
| Disease | hypertension;GAD | 
| Disease | prostate cancer;GAD | 
| Disease | lung cancer;GAD | 
| Disease | nephropathy in other diseases;GAD | 
| Disease | Parkinson's disease;GAD | 
| Disease | schizophrenia tardive dyskinesia;GAD | 
| Disease | diabetes, neurological manifestations;GAD | 
| Disease | PHARMACOGENOMIC;GAD | 
| Disease | cardiomyopathy;GAD | 
| Disease | Systemic infection;FunDO | 
| Disease | METABOLIC;GAD | 
| Disease | Schizophrenia;FunDO | 
| Disease | Cirrhosis;FunDO | 
| Disease | Alzheimer's disease;FunDO | 
| Disease | psoriatic arthritis;GAD | 
| Disease | colorectal cancer;GAD | 
| Disease | Pre-Eclampsia;FunDO | 
| Disease | diabetic polyneuropathy;GAD | 
| Disease | PSYCH;GAD | 
| Disease | diabetes, type 1;GAD | 
| Disease | Lung Neoplasms;GAD | 
| Disease | liver injury, drug-induced;GAD | 
| Disease | Psychotic disorder;FunDO | 
| Disease | CARDIOVASCULAR;GAD | 
| Disease | Kuhnt-Junius degeneration;FunDO | 
| Disease | Drug-Induced dyskinesia;FunDO | 
| Disease | Pancreas disease;FunDO | 
| Disease | steatohepatitis, non-alcoholic;GAD | 
| Disease | Chronic obstructive airway disease;FunDO | 
| Disease | NEUROLOGICAL;GAD | 
| Disease | tardive dyskinesia;GAD | 
| Disease | Behcet's Disease;GAD | 
| Disease | nephropathy, diabetic;GAD | 
| Disease | Behcet syndrome;FunDO | 
| Disease | cholesterol;GAD | 
| Disease | RENAL;GAD | 
| Disease | leukemia;GAD | 
| Disease | liver cancer;GAD | 
| Disease | CANCER;GAD | 
| Disease | schizophrenia;GAD | 
| Disease | Barrett's esophagus;FunDO | 
| Disease | Diabetes Mellitus;GAD | 
| Disease | aging and longevity;GAD | 
| Disease | diabetic nephropathy diabetic neuropathy;GAD | 
| Disease | Arthritis;FunDO | 
| Disease | stomach cancer;GAD | 
| Disease | Ankylosing spondylitis;FunDO | 
| External Links | |
| Links to Entrez Gene | 6648 | 
| Links to all GeneRIF Items | 6648 | 
| Links to iHOP | 6648 | 
| Sequence Information | |
| Nucleotide Sequence | >6648 : length: 669 atgttgagccgggcagtgtgcggcaccagcaggcagctggctccggttttggggtatctg ggctccaggcagaagcacagcctccccgacctgccctacgactacggcgccctggaacct cacatcaacgcgcagatcatgcagctgcaccacagcaagcaccacgcggcctacgtgaac aacctgaacgtcaccgaggagaagtaccaggaggcgttggccaagggagatgttacagcc cagatagctcttcagcctgcactgaagttcaatggtggtggtcatatcaatcatagcatt ttctggacaaacctcagccctaacggtggtggagaacccaaaggggagttgctggaagcc atcaaacgtgactttggttcctttgacaagtttaaggagaagctgacggctgcatctgtt ggtgtccaaggctcaggttggggttggcttggtttcaataaggaacggggacacttacaa attgctgcttgtccaaatcaggatccactgcaaggaacaacaggccttattccactgctg gggattgatgtgtgggagcacgcttactaccttcagtataaaaatgtcaggcctgattat ctaaaagctatttggaatgtaatcaactgggagaatgtaactgaaagatacatggcttgc aaaaagtaa | 
| Protein Sequence | >6648 : length: 222 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN NLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEA IKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLL GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK | 
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