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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 6776 |
Name | STAT5A |
Synonym | MGF|STAT5;signal transducer and activator of transcription 5A;STAT5A;signal transducer and activator of transcription 5A |
Definition | - |
Position | 17q11.2 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | Acts as a key tumor suppressor by reciprocally inhibiting expression of oncogenic nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) in T-cell anaplastic large cell lymphomas. |
| More detail of all 1 literatures about STAT5A | |
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Pathways and Diseases |
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Pathway | Signaling events mediated by TCPTP;PID Curated;200065 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | IL23-mediated signaling events;PID Curated;200131 |
Pathway | CXCR4-mediated signaling events;PID Curated;200083 |
Pathway | IL12-mediated signaling events;PID Curated;200034 |
Pathway | PDGFR-beta signaling pathway;PID Curated;200127 |
Pathway | Signaling by PDGF;Reactome;REACT:16888 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Pathway | Trk receptor signaling mediated by PI3K and PLC-gamma;PID Curated;200183 |
Pathway | Chronic myeloid leukemia;KEGG PATHWAY;hsa05220 |
Pathway | EPO signaling pathway;PID Curated;200157 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | EGF receptor signaling pathway;PANTHER;P00018 |
Pathway | IL2-mediated signaling events;PID Curated;200082 |
Pathway | CD40/CD40L signaling;PID Curated;200031 |
Pathway | bioactive peptide induced signaling pathway;PID BioCarta;100226 |
Pathway | RAC1 signaling pathway;PID Curated;200190 |
Pathway | Signaling events mediated by PTP1B;PID Curated;200033 |
Pathway | ErbB signaling pathway;KEGG PATHWAY;hsa04012 |
Pathway | JAK/STAT signaling pathway;PANTHER;P00038 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | Angiopoietin receptor Tie2-mediated signaling;PID Curated;200066 |
Pathway | il22 soluble receptor signaling pathway;PID BioCarta;100131 |
Pathway | ErbB4 signaling events;PID Curated;200009 |
Pathway | IL27-mediated signaling events;PID Curated;200023 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | Signaling events mediated by Stem cell factor receptor (c-Kit);PID Curated;200156 |
Pathway | GMCSF-mediated signaling events;PID Curated;200015 |
Pathway | Acute myeloid leukemia;KEGG PATHWAY;hsa05221 |
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External Links |
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Links to Entrez Gene | 6776 |
Links to all GeneRIF Items | 6776 |
Links to iHOP | 6776 |
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Sequence Information |
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Nucleotide Sequence |
>6776 : length: 2385 atggcgggctggatccaggcccagcagctgcagggagacgcgctgcgccagatgcaggtg ctgtacggccagcacttccccatcgaggtccggcactacttggcccagtggattgagagc cagccatgggatgccattgacttggacaatccccaggacagagcccaagccacccagctc ctggagggcctggtgcaggagctgcagaagaaggcggagcaccaggtgggggaagatggg tttttactgaagatcaagctggggcactacgccacgcagctccagaaaacatatgaccgc tgccccctggagctggtccgctgcatccggcacattctgtacaatgaacagaggctggtc cgagaagccaacaattgcagctctccggctgggatcctggttgacgccatgtcccagaag caccttcagatcaaccagacatttgaggagctgcgactggtcacgcaggacacagagaat gagctgaagaaactgcagcagactcaggagtacttcatcatccagtaccaggagagcctg aggatccaagctcagtttgcccagctggcccagctgagcccccaggagcgtctgagccgg gagacggccctccagcagaagcaggtgtctctggaggcctggttgcagcgtgaggcacag acactgcagcagtaccgcgtggagctggccgagaagcaccagaagaccctgcagctgctg cggaagcagcagaccatcatcctggatgacgagctgatccagtggaagcggcggcagcag ctggccgggaacggcgggccccccgagggcagcctggacgtgctacagtcctggtgtgag aagttggccgagatcatctggcagaaccggcagcagatccgcagggctgagcacctctgc cagcagctgcccatccccggcccagtggaggagatgctggccgaggtcaacgccaccatc acggacattatctcagccctggtgaccagcacattcatcattgagaagcagcctcctcag gtcctgaagacccagaccaagtttgcagccaccgtacgcctgctggtgggcgggaagctg aacgtgcacatgaatcccccccaggtgaaggccaccatcatcagtgagcagcaggccaag tctctgcttaaaaatgagaacacccgcaacgagtgcagtggtgagatcctgaacaactgc tgcgtgatggagtaccaccaagccacgggcaccctcagtgcccacttcaggaacatgtca ctgaagaggatcaagcgtgctgaccggcggggtgcagagtccgtgacagaggagaagttc acagtcctgtttgagtctcagttcagtgttggcagcaatgagcttgtgttccaggtgaag actctgtccctacctgtggttgtcatcgtccacggcagccaggaccacaatgccacggct actgtgctgtgggacaatgcctttgctgagccgggcagggtgccatttgccgtgcctgac aaagtgctgtggccgcagctgtgtgaggcgctcaacatgaaattcaaggccgaagtgcag agcaaccggggcctgaccaaggagaacctcgtgttcctggcgcagaaactgttcaacaac agcagcagccacctggaggactacagtggcctgtccgtgtcctggtcccagttcaacagg gagaacttgccgggctggaactacaccttctggcagtggtttgacggggtgatggaggtg ttgaagaagcaccacaagccccactggaatgatggggccatcctaggttttgtgaataag caacaggcccacgacctgctcatcaacaagcccgacgggaccttcttgttgcgctttagt gactcagaaatcgggggcatcaccatcgcctggaagtttgactccccggaacgcaacctg tggaacctgaaaccattcaccacgcgggatttctccatcaggtccctggctgaccggctg ggggacctgagctatctcatctatgtgtttcctgaccgccccaaggatgaggtcttctcc aagtactacactcctgtgctggctaaagctgttgatggatatgtgaaaccacagatcaag caagtggtccctgagtttgtgaatgcatctgcagatgctgggggcagcagcgccacgtac atggaccaggccccctccccagctgtgtgcccccaggctccctataacatgtacccacag aaccctgaccatgtactcgatcaggatggagaattcgacctggatgagaccatggatgtg gccaggcacgtggaggaactcttacgccgaccaatggacagtcttgactcccgcctctcg ccccctgccggtcttttcacctctgccagaggctccctctcatga |
Protein Sequence |
>6776 : length: 794 MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQL LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQKTYDRCPLELVRCIRHILYNEQRLV REANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL RIQAQFAQLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL NVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMS LKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATA TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN SSSHLEDYSGLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNK QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPERNLWNLKPFTTRDFSIRSLADRL GDLSYLIYVFPDRPKDEVFSKYYTPVLAKAVDGYVKPQIKQVVPEFVNASADAGGSSATY MDQAPSPAVCPQAPYNMYPQNPDHVLDQDGEFDLDETMDVARHVEELLRRPMDSLDSRLS PPAGLFTSARGSLS |