|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 688 |
Name | KLF5 |
Synonym | BTEB2|CKLF|IKLF;Kruppel-like factor 5 (intestinal);KLF5;Kruppel-like factor 5 (intestinal) |
Definition | BTE-binding protein 2|GC box binding protein 2|GC-box-binding protein 2|Krueppel-like factor 5|basic transcription element binding protein 2|basic transcription element-binding protein 2|colon krueppel-like factor|colon kruppel-like factor|intestinal-enri |
Position | 13q22.1 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 2 PubMed records as below. |
|
Evidence Status |
Description |
reviewed | Gene deletion and loss of expression and cell growth suppression indicate that KLF5 may be tumor suppressor gene at 13q21 in prostate cancer. Mutation and promoter methylation do not commonly inactivate KLF5 in prostate cancer. |
reviewed | A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer. |
| More detail of all 2 literatures about KLF5 | |
|
External Links |
|
Links to Entrez Gene | 688 |
Links to all GeneRIF Items | 688 |
Links to iHOP | 688 |
|
Sequence Information |
|
Nucleotide Sequence |
>688 : length: 1374 atggctacaagggtgctgagcatgagcgcccgcctgggacccgtgccccagccgccggcg ccgcaggacgagccggtgttcgcgcagctcaagccggtgctgggcgccgcgaatccggcc cgcgacgcggcgctcttccccggcgaggagctgaagcacgcgcaccaccgcccgcaggcg cagcccgcgcccgcgcaggccccgcagccggcccagccgcccgccaccggcccgcggctg cctccagaggacctggtccagacaagatgtgaaatggagaagtatctgacacctcagctt cctccagttcctataattccagagcataaaaagtatagacgagacagtgcctcagtcgta gaccagttcttcactgacactgaagggttaccttacagtatcaacatgaacgtcttcctc cctgacatcactcacctgagaactggcctctacaaatcccagagaccgtgcgtaacacac atcaagacagaacctgttgccattttcagccaccagagtgaaacgactgcccctcctccg gccccgacccaggccctccctgagttcaccagtatattcagctcacaccagaccgcagct ccagaggtgaacaatattttcatcaaacaagaacttcctacaccagatcttcatctttct gtccctacccagcagggccacctgtaccagctactgaatacaccggatctagatatgccc agttctacaaatcagacagcagcaatggacactcttaatgtttctatgtcagctgccatg gcaggccttaacacacacacctctgctgttccgcagactgcagtgaaacaattccagggc atgcccccttgcacatacacaatgccaagtcagtttcttccacaacaggccacttacttt cccccgtcaccaccaagctcagagcctggaagtccagatagacaagcagagatgctccag aatttaaccccacctccatcctatgctgctacaattgcttctaaactggcaattcacaat ccaaatttacccaccaccctgccagttaactcacaaaacatccaacctgtcagatacaat agaaggagtaaccccgatttggagaaacgacgcatccactactgcgattaccctggttgc acaaaagtttataccaagtcttctcatttaaaagctcacctgaggactcacactggtgaa aagccatacaagtgtacctgggaaggctgcgactggaggttcgcgcgatcggatgagctg acccgccactaccggaagcacacaggcgccaagcccttccagtgcggggtgtgcaaccgc agcttctcgcgctctgaccacctggccctgcatatgaagaggcaccagaactga |
Protein Sequence |
>688 : length: 457 MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQA QPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVV DQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPP APTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMP SSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYF PPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYN RRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDEL TRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN |