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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 7159 |
Name | TP53BP2 |
Synonym | 53BP2|ASPP2|BBP|P53BP2|PPP1R13A;tumor protein p53 binding protein, 2;TP53BP2;tumor protein p53 binding protein, 2 |
Definition | BCL2-binding protein|apoptosis-stimulating of p53 protein 2|apoptosis-stimulating protein of p53, 2|renal carcinoma antigen NY-REN-51|tumor suppressor p53-binding protein 2 |
Position | 1q41 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 3 PubMed records as below. |
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Evidence Status |
Description |
reviewed | Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host. |
reviewed | New insights into the expanding complexity of the tumor suppressor ASPP2. |
reviewed | ASPP2 is a haploinsufficient tumor suppressor that shares overlapping function(s) with p53 in mouse development and tumor suppression. |
| More detail of all 3 literatures about TP53BP2 | |
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External Links |
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Links to Entrez Gene | 7159 |
Links to all GeneRIF Items | 7159 |
Links to iHOP | 7159 |
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Sequence Information |
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Nucleotide Sequence |
>7159 : length: 3405 atgcggttcgggtccaagatgatgccgatgtttcttaccgtgtatctcagtaacaatgag cagcacttcacagaagttccagttactccagaaacaatatgcagagacgtggtggatctg tgcaaagaacccggcgagagtgattgccatttggctgaagtgtggtgtggctctgaacgt ccagttgcggataatgagcgaatgtttgatgttcttcaacgatttggaagtcagaggaac gaagttcgcttcttccttcgtcatgaacgcccccctggcagggacattgtgagtggacca agatctcaggatccaagtttaaaaagaaatggtgtaaaagttcctggtgaatatcgaaga aaggagaacggtgttaatagtcctaggatggatctgactcttgctgaacttcaggaaatg gcatctcgccagcagcaacagattgaagcccagcaacaattgctggcaactaaggaacag cgcttaaagtttttgaaacaacaagatcagcgacaacagcaacaagttgctgagcaggag aaacttaaaaggctaaaagaaatagctgagaatcaggaagctaagctaaaaaaagtgaga gcacttaaaggccacgtggaacagaagagactaagcaatgggaaacttgtggaggaaatt gaacagatgaataatttgttccagcaaaaacagagggagctcgtcctggctgtgtcaaaa gtagaagaactgaccaggcagctagagatgctcaagaacggcaggatcgacagccaccat gacaatcagtctgcagtggctgagcttgatcgcctctataaggagctgcagctaagaaac aaattgaatcaagagcagaatgccaagctacaacaacagagggagtgtttgaataagcgt aattcagaagtggcagtcatggataagcgtgttaatgagctgagggaccggctgtggaag aagaaggcagctctacagcaaaaagaaaatctaccagtttcatctgatggaaatcttccc cagcaagccgcgtcagccccaagccgtgtggctgcagtaggtccctatatccagtcgtct actatgcctcggatgccctcaaggcctgaattgctggtgaagccagccctgccggatggt tccttggtcattcaggcttcagaggggccgatgaaaatacagacactgcccaacatgaga tctggggctgcttcacaaactaaaggctctaaaatccatccagttggccctgattggagt ccttcaaatgcagatcttttcccaagccaaggctctgcttctgtacctcaaagcactggg aatgctctggatcaagttgatgatggagaggttccgctgagggagaaagagaagaaagtg cgtccgttctcaatgtttgatgcagtagaccagtccaatgccccaccttcctttggtact ctgaggaagaaccagagcagtgaagatatcttgcgggatgctcaggttgcaaataaaaat gtggctaaagtaccacctcctgttcctacaaaaccaaaacagattaatttgccttatttt ggacaaactaatcagccaccttcagacattaagccagacggaagttctcagcagttgtca acagttgttccgtccatgggaactaaaccaaaaccagcagggcagcagccgagagtgctg ctatctcccagcataccttcggttggccaagaccagaccctttctccaggttctaagcaa gaaagtccacctgctgctgccgtccggccctttactccccagccttccaaagacacctta cttccacccttcagaaaaccccagaccgtggcagcaagttcaatatattccatgtatacg caacagcaggcgccaggaaaaaacttccagcaggctgtgcagagcgcgttgaccaagact cataccagagggccacacttttcaagtgtatatggtaagcctgtaattgctgctgcccag aatcaacagcagcacccagagaacatttattccaatagccagggcaagcctggcagtcca gaacctgaaacagagcctgtttcttcagttcaggagaaccatgaaaacgaaagaattcct cggccactcagcccaactaaattactgcctttcttatctaatccttaccgaaaccagagt gatgctgacctagaagccttacgaaagaaactgtctaacgcaccaaggcctctaaagaaa cgtagttctattacagagccagagggtcctaatgggccaaatattcagaagcttttatat cagaggaccaccatagcggccatggagaccatctctgtcccatcatacccatccaagtca gcttctgtgactgccagctcagaaagcccagtagaaatccagaatccatatttacatgtg gagcccgaaaaggaggtggtctctctggttcctgaatcattgtccccagaggatgtgggg aatgccagtacagagaacagtgacatgccagctccttctccaggccttgattatgagcct gagggagtcccagacaacagcccaaatctccagaataacccagaagaaccaaatccagag gctccacatgtgcttgatgtgtacctggaggagtaccctccatacccacccccaccatac ccatctggggagcctgaagggcccggagaagactcggtgagcatgcgcccgcctgaaatc accgggcaggtctctctgcctcctggtaaaaggacaaacttgcgtaaaactggctcagag cgtatcgctcatggaatgagggtgaaattcaacccccttgctttactgctagattcgtct ttggagggagaatttgaccttgtacagagaattatttatgaggttgatgacccaagcctc cccaatgatgaaggcatcacggctcttcacaatgctgtgtgtgcaggccacacagaaatc gttaagttcctggtacagtttggtgtaaatgtaaatgctgctgatagtgatggatggact ccattacattgtgctgcctcatgtaacaacgtccaagtgtgtaagtttttggtggagtca ggagccgctgtgtttgccatgacctacagtgacatgcagactgctgcagataagtgcgag gaaatggaggaaggctacactcagtgctcccaatttctttatggagttcaggagaagatg ggcataatgaataaaggagtcatttatgcgctttgggattatgaacctcagaatgatgat gagctgcccatgaaagaaggagactgcatgacaatcatccacagggaagacgaagatgaa atcgaatggtggtgggcgcgccttaatgataaggagggatatgttccacgtaacttgctg ggactgtacccaagaattaaaccaagacaaaggagcttggcctga |
Protein Sequence |
>7159 : length: 1134 MRFGSKMMPMFLTVYLSNNEQHFTEVPVTPETICRDVVDLCKEPGESDCHLAEVWCGSER PVADNERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRR KENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQE KLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSK VEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKR NSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSS TMPRMPSRPELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWS PSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGT LRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLS TVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTL LPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQ NQQQHPENIYSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQS DADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKS ASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEP EGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEI TGQVSLPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSL PNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVES GAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDD ELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA |