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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 7251 |
Name | TSG101 |
Synonym | TSG10|VPS23;tumor susceptibility gene 101;TSG101;tumor susceptibility gene 101 |
Definition | ESCRT-I complex subunit TSG101|tumor susceptibility gene 101 protein|tumor susceptibility protein |
Position | 11p15 |
Gene Type | protein-coding |
Source | Count: 2; TAG,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
reviewed | Aberrant splicing of the TSG101 tumor suppressor gene in human breast and ovarian cancers. |
reviewed | Overexpression of tumor susceptibility gene TSG101 in human papillary thyroid carcinomas. |
| More detail of all 2 literatures about TSG101 | |
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Pathways and Diseases |
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Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Internalization of ErbB1;PID Curated;200146 |
Pathway | Glucocorticoid receptor regulatory network;PID Curated;200077 |
Disease | HIV infection;FunDO |
Disease | Breast cancer;OMIM |
Disease | Ovarian cancer;FunDO |
Disease | Prostate cancer;FunDO |
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External Links |
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Links to Entrez Gene | 7251 |
Links to all GeneRIF Items | 7251 |
Links to iHOP | 7251 |
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Sequence Information |
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Nucleotide Sequence |
>7251 : length: 1173 atggcggtgtcggagagccagctcaagaaaatggtgtccaagtacaaatacagagaccta actgtacgtgaaactgtcaatgttattactctatacaaagatctcaaacctgttttggat tcatatgtttttaacgatggcagttccagggaactaatgaacctcactggaacaatccct gtgccttatagaggtaatacatacaatattccaatatgcctatggctactggacacatac ccatataatccccctatctgttttgttaagcctactagttcaatgactattaaaacagga aagcatgttgatgcaaatgggaagatatatcttccttatctacatgaatggaaacaccca cagtcagacttgttggggcttattcaggtcatgattgtggtatttggagatgaacctcca gtcttctctcgtcctatttcggcatcctatccgccataccaggcaacggggccaccaaat acttcctacatgccaggcatgccaggtggaatctctccatacccatccggataccctccc aatcccagtggttacccaggctgtccttacccacctggtggtccatatcctgccacaaca agttctcagtacccttctcagcctcctgtgaccactgttggtcccagtagggatggcaca atcagcgaggacaccatccgagcctctctcatctctgcggtcagtgacaaactgagatgg cggatgaaggaggaaatggatcgtgcccaggcagagctcaatgccttgaaacgaacagaa gaagacctgaaaaagggtcaccagaaactggaagagatggttacccgtttagatcaagaa gtagccgaggttgataaaaacatagaacttttgaaaaagaaggatgaagaactcagttct gctctggaaaaaatggaaaatcagtctgaaaacaatgatatcgatgaagttatcattccc acagctcccttatacaaacagatcctgaatctgtatgcagaagaaaacgctattgaagac actatcttttacttgggagaagccttgagaaggggcgtgatagacctggatgtcttcctg aagcatgtacgtcttctgtcccgtaaacagttccagctgagggcactaatgcaaaaagca agaaagactgccggtctcagtgacctctactga |
Protein Sequence |
>7251 : length: 390 MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIP VPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHP QSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPP NPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRW RMKEEMDRAQAELNALKRTEEDLKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSS ALEKMENQSENNDIDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFL KHVRLLSRKQFQLRALMQKARKTAGLSDLY |