Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

7791

Name

ZYX

Synonym

ESP-2|HED-2;zyxin;ZYX;zyxin

Definition

zyxin-2

Position

7q32

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

potential

"Within Ewing tumor cells, zyxin is expressed at very low levels and remains diffusely distributed throughout the cytoplasm, instead of concentrating in actin-rich dynamic structures. Zyxin has tumor suppressor activity in Ewing tumor cells."
More detail of all 1 literatures about ZYX

Pathways and Diseases

Pathway

erk and pi-3 kinase are necessary for collagen binding in corneal epithelia;PID BioCarta;100184

Pathway

Stabilization and expansion of the E-cadherin adherens junction;PID Curated;200155

Pathway

E-cadherin signaling in keratinocytes;PID Curated;200125

Pathway

integrin signaling pathway;PID BioCarta;100123

Pathway

Focal adhesion;KEGG PATHWAY;hsa04510

External Links

Links to Entrez Gene

7791

Links to all GeneRIF Items

7791

Links to iHOP

7791

Sequence Information

Nucleotide Sequence

>7791 : length: 1719
atggcggccccccgcccgtctcccgcgatctccgtttcggtctcggctccggctttttac
gccccgcagaagaagttcggccctgtggtggccccaaagcccaaagtgaatcccttccgg
cccggggacagcgagcctcccccggcacccggggcccagcgcgcacagatgggccgggtg
ggcgagattcccccgccgcccccggaagactttcccctgcctccacctccccttgctggg
gatggcgacgatgcagagggtgctctgggaggtgccttcccgccgccccctcccccgatc
gaggaatcatttccccctgcgcctctggaggaggagatcttcccttccccgccgcctcct
ccggaggaggagggagggcctgaggcccccataccgcccccaccacagcccagggagaag
gtgagcagtattgatttggagatcgactctctgtcctcactgctggatgacatgaccaag
aatgatcctttcaaagcccgggtgtcatctggatatgtgcccccaccagtggccactcca
ttcagttccaagtccagtaccaagcctgcagccgggggcacagcacccctgcctccttgg
aagtccccttccagctcccagcctctgccccaggttccggctccggctcagagccagaca
cagttccatgttcagccccagccccagcccaagcctcaggtccaactccatgtccagtcc
cagacccagcctgtgtctttggctaacacccagccccgagggcccccagcctcatctccg
gctccagcccctaagttttctccagtgactcctaagtttactcctgtggcttccaagttc
agtcctggagccccaggtggatctgggtcacaaccaaatcaaaaattggggcaccccgaa
gctctttctgctggcacaggctcccctcaacctcccagcttcacctatgcccagcagagg
gagaagccccgagtgcaggagaagcagcaccccgtgcccccaccggctcagaaccaaaac
caggtgcgctcccctggggccccagggcccctgactctgaaggaggtggaggagctggag
cagctgacccagcagctaatgcaggacatggagcatcctcagaggcagaatgtggctgtc
aacgaactctgcggccgatgccatcaacccctggcccgggcgcagccagccgtccgcgct
ctagggcagctgttccacatcgcctgcttcacctgccaccagtgtgcgcagcagctccag
ggccagcagttctacagtctggagggggcgccgtactgcgagggctgttacactgacacc
ctggagaagtgtaacacctgcggggagcccatcactgaccgcatgctgagggccacgggc
aaggcctatcacccgcactgcttcacctgtgtggtctgcgcccgccccctggagggcacc
tccttcatcgtggaccaggccaaccggccccactgtgtccccgactaccacaagcagtac
gccccgaggtgctccgtctgctctgagcccatcatgcctgagcctggccgagatgagact
gtgcgagtggtcgccctggacaagaacttccacatgaagtgttacaagtgtgaggactgc
gggaagcccctgtcgattgaggcagatgacaatggctgcttccccctggacggtcacgtg
ctctgtcggaagtgccacactgctagagcccagacctga

Protein Sequence

>7791 : length: 572
MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV
GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAPLEEEIFPSPPPP
PEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATP
FSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQS
QTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAPGGSGSQPNQKLGHPE
ALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEELE
QLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQ
GQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGT
SFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDC
GKPLSIEADDNGCFPLDGHVLCRKCHTARAQT



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