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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 79192 |
Name | IRX1 |
Synonym | IRX-5|IRXA1;iroquois homeobox 1;IRX1;iroquois homeobox 1 |
Definition | homeodomain protein IRXA1|iroquois homeobox protein 1|iroquois-class homeodomain protein IRX-1 |
Position | 5p15.3 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
reviewed | Homeobox gene IRX1 is a tumor suppressor gene in gastric carcinoma. |
potential | "Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma. Overexpression of the three most frequently down-regulated candidates, SLC5A8, IRX1, and EBF3, validated their tumor suppressor potential by growth curve analysis and colony formation assay." |
| More detail of all 2 literatures about IRX1 | |
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External Links |
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Links to Entrez Gene | 79192 |
Links to all GeneRIF Items | 79192 |
Links to iHOP | 79192 |
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Sequence Information |
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Nucleotide Sequence |
>79192 : length: 1443 atgtccttcccgcagctgggctacccgcagtacctgagcgccgcggggccgggcgcctac ggcggcgagcgcccgggggtgctggccgcggccgctgcggcggctgccgccgcctcgtcg ggccgaccgggggccgcggagctgggcggcggggcaggcgcggctgcagtcacctcggtg ctgggcatgtacgcggcggcggggccgtacgcgggcgcgcccaactacagcgccttcctg ccctacgccgcggatctcagcctcttctcgcagatgggctcgcagtatgaactgaaggac aaccctggggtgcaccccgccaccttcgcagcccacacggcgccggcttattacccctac ggccagttccaatacggggaccccgggcggcccaagaacgccacccgcgagagcaccagc acgctcaaggcctggctcaacgagcaccgcaagaatccctaccccaccaagggcgagaag atcatgctggccatcatcaccaagatgaccctcacgcaggtctccacctggttcgccaac gcgcgccggcgcctcaagaaggagaacaaggtgacatggggagcgcgcagcaaggaccag gaagatggagcgctcttcggcagcgacaccgagggcgacccggagaaggccgaggacgac gaggagatcgacctggaaagcatcgacattgacaagatcgacgagcacgatggcgaccag agcaacgaggatgacgaggacaaggccgaggctccgcacgcgcccgcagccccttctgct cttgcccgggaccaaggctcgccgctggcagcagccgacgttctcaagccccaggactcg cccttgggcctggcaaaggaggccccagagccgggcagcacgcgcctgctgagccccggc gctgcagcgggcggcctgcagggtgcgccgcacggcaagcccaagatctggtcgctggcg gagacagccacgagccccgacggtgcgcccaaggcttcgccaccaccacccgcgggccac cccggcgcgcacgggccctccgccggggcgccgctgcaacaccccgccttcctgcctagc cacggactgtacacctgccacatcggcaagttctccaactggaccaacagcgcattcctc gcacagggctccctgctcaacatgcgctccttcctgggcgttggcgctccccacgccgcg ccccatggccctcaccttcctgcacctccaccaccgcagccgccggtcgctattgccccg ggggcactcaatggagacaaggcctcggtccgcagcagccccacgctcccagagagagac ctcgtccccaggccagattcgccggcacagcagttaaagtcgcccttccagccggtacgc gacaactctctggccccgcaggagggaacgccgcggatcctagcagccctcccgtccgcc tga |
Protein Sequence |
>79192 : length: 480 MSFPQLGYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGAAELGGGAGAAAVTSV LGMYAAAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKDNPGVHPATFAAHTAPAYYPY GQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFAN ARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEEIDLESIDIDKIDEHDGDQ SNEDDEDKAEAPHAPAAPSALARDQGSPLAAADVLKPQDSPLGLAKEAPEPGSTRLLSPG AAAGGLQGAPHGKPKIWSLAETATSPDGAPKASPPPPAGHPGAHGPSAGAPLQHPAFLPS HGLYTCHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAP GALNGDKASVRSSPTLPERDLVPRPDSPAQQLKSPFQPVRDNSLAPQEGTPRILAALPSA |