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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 79648 |
Name | MCPH1 |
Synonym | BRIT1|MCT;microcephalin 1;MCPH1;microcephalin 1 |
Definition | BRCT-repeat inhibitor of TERT expression 1|microcephalin |
Position | 8p23.1 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | BRIT1 is a crucial DNA damage regulator in the ATM/ATR pathways and suggest that it functions as a tumor suppressor gene. |
| More detail of all 1 literatures about MCPH1 | |
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External Links |
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Links to Entrez Gene | 79648 |
Links to all GeneRIF Items | 79648 |
Links to iHOP | 79648 |
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Sequence Information |
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Nucleotide Sequence |
>79648 : length: 1833 atggcggcccccatcctgaaagatgtagtggcctatgttgaagtgtggtcatccaatgga acagaaaattattcaaagacatttacaacacagcttgtggatatgggggcaaaggtttca aaaacttttaacaaacaagtaactcacgttatcttcaaagatggctaccagagcacttgg gacaaagctcagaagagaggcgtaaagctcgtttcggtgctctgggtggaaaaatgcagg acagctggagcacacattgatgaatcattgttccctgcagctaatatgaatgaacactta tcaagcctaattaaaaaaaaacgtaaatgtatgcagcccaaagattttaattttaaaaca ccagaaaatgataagagatttcagaagaaatttgagaaaatggctaaagagctacaaagg caaaaaacaaatctagatgatgatgtacctattctcttatttgaatctaatggttcatta atatatactcccacaattgaaattaatagtagtcaccacagcgcaatggagaagagatta caagagatgaaggagaaaagggaaaatctttcccccacctcttcccaaatgattcagcag tctcatgataatccaagtaactctctgtgtgaagcacctttgaacatttcacgtgatact ttgtgttcagatgaatactttgctggtggcttacactcatcttttgatgatctttgtgga aactcaggatgtggaaatcaggaaaggaagttggaaggatccattaatgacattaaaagt gatgtgtgtatttcttcacttgtattgaaagcaaataatattcattcatcaccatctttc actcacctcgataaatcaagtcctcagaaatttctgagtaatctttcaaaggaagaaata aacttgcaaagaaatattgcaggtaaagtagtcacccctgaccaaaagcaggctgcaggt atgtctcaggagacgtttgaagagaagtatcgtttgtctcctaccttatcttcaacaaaa ggccaccttttgatacattcaagacccaggagttcctcagtaaagagaaaaagagtatca catggctcccattcacctccgaaggaaaaatgcaagagaaagaggagcaccaggagatct atcatgccgaggctgcagctgtgcaggtcggaagacaggctgcagcacgtggcgggacct gccctggaggctcttagctgtggggagtcttcatatgatgactatttttcacctgataat cttaaggaaaggtattcagagaatcttcctcctgaatctcagctgccatcaagccctgct cagttgagctgcagaagtctttctaagaaggagagaacaagcatatttgaaatgtctgat ttttcctgcgttggcaaaaaaaccagaacagttgacattaccaatttcacagcaaaaacc atctccagtcctcggaaaactggaaatggtgaaggccgtgcaacttcgagttgcgtgact tctgcccctgaagaagccctaaggtgttgtagacaggctgggaaagaagacgcatgccca gagggaaatggcttttcttacaccattgaggaccctgctcttccaaaaggacatgatgat gatttaactcctttggaaggaagccttgaagaaatgaaagaagcggttggtctgaaaagc acacagaacaaaggtaccacttccaaaatatcaaactcctctgaaggcgaagcccagagt gaacatgagccatgttttatagttgactgtaacatggagacgtctacagaagagaaggaa aacttacccggaggatacagtggaagtatgtga |
Protein Sequence |
>79648 : length: 610 MAAPILKDVVAYVEVWSSNGTENYSKTFTTQLVDMGAKVSKTFNKQVTHVIFKDGYQSTW DKAQKRGVKLVSVLWVEKCRTAGAHIDESLFPAANMNEHLSSLIKKKRKCMQPKDFNFKT PENDKRFQKKFEKMAKELQRQKTNLDDDVPILLFESNGSLIYTPTIEINSSHHSAMEKRL QEMKEKRENLSPTSSQMIQQSHDNPSNSLCEAPLNISRDTLCSDEYFAGGLHSSFDDLCG NSGCGNQERKLEGSINDIKSDVCISSLVLKANNIHSSPSFTHLDKSSPQKFLSNLSKEEI NLQRNIAGKVVTPDQKQAAGMSQETFEEKYRLSPTLSSTKGHLLIHSRPRSSSVKRKRVS HGSHSPPKEKCKRKRSTRRSIMPRLQLCRSEDRLQHVAGPALEALSCGESSYDDYFSPDN LKERYSENLPPESQLPSSPAQLSCRSLSKKERTSIFEMSDFSCVGKKTRTVDITNFTAKT ISSPRKTGNGEGRATSSCVTSAPEEALRCCRQAGKEDACPEGNGFSYTIEDPALPKGHDD DLTPLEGSLEEMKEAVGLKSTQNKGTTSKISNSSEGEAQSEHEPCFIVDCNMETSTEEKE NLPGGYSGSM |