|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 7982 |
Name | ST7 |
Synonym | ETS7q|FAM4A|FAM4A1|HELG|RAY1|SEN4|TSG7;suppression of tumorigenicity 7;ST7;suppression of tumorigenicity 7 |
Definition | family with sequence similarity 4, subfamily A, member 1|suppression of tumorigenicity 7 (breast)|suppressor of tumorigenicity 7 protein |
Position | 7q31.2 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 6 PubMed records as below. |
|
Evidence Status |
Description |
reviewed | Novel susceptibility locus for mouse hepatomas: evidence for a conserved tumor suppressor gene. |
reviewed | Loss of heterozygosity in human primary prostate carcinomas: a possible tumor suppressor gene at 7q31.1. |
reviewed | Allelic loss at 7q31.1 in human primary ovarian carcinomas suggests the existence of a tumor suppressor gene. |
potential | The RAY1/ST7 tumor-suppressor locus on chromosome 7q31 represents a complex multi-transcript system. |
reviewed | Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31. |
reviewed | Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes. |
| More detail of all 6 literatures about ST7 | |
|
External Links |
|
Links to Entrez Gene | 7982 |
Links to all GeneRIF Items | 7982 |
Links to iHOP | 7982 |
|
Sequence Information |
|
Nucleotide Sequence |
>7982 : length: 1665 atggctgaagcggccacgggctttctggagcagctcaagtcctgcatagtttggtcttgg acgtatctgtggaccgtgtggttcttcatcgtgctattcctggtctacatcctgcgggtg cctttgaaaatcaacgacaacttgagcacagtgagcatgtttttgaacacattaacaccg aagttctacgtggccctaacaggcacttcctcactaatatcagggcttattttgatattt gaatggtggtattttcgcaaatacggaacttcattcattgaacaagtctcagtaagccac ttgcgcccccttctgggaggggttgacaacaactcttccaacaattctaattccagtaac ggggactcagattccaataggcaaagtgtctcagaatgcaaagtatggcgaaatccacta aatttatttaggggtgctgaatacaatcggtatacttgggtgacaggacgagagcctctt acttactatgacatgaatctctctgcccaagaccaccagacattctttacttgtgactcg gaccatctgcgtcccgcagatgcaataatgcagaaagcctggagagagagaaacccccaa gctaggatttctgcagctcatgaagccttggagataaatgagtgtgcaactgcttatatt ctcttggctgaagaggaagcaacaaccattgctgaagcagaaaaattatttaagcaggcc ctgaaggctggagatggctgttaccgacgctctcagcagctacaacatcatggatcccag tatgaagcccaacatagacgagacaccaatgtcttggtgtacatcaaaagaaggctagca atgtgtgccagaagactcgggaggaccagggaagcagtgaaaatgatgagagatttaatg aaggagttcccccttctgagtatgttcaatatccatgaaaaccttttagaagcccttctg gaactacaagcatatgctgatgttcaggcagtcttagcaaagtatgatgatataagctta ccaaagtcagcaacaatatgctacacagctgctttgctcaaagcaagagctgtctctgac aaattctctcctgaggctgcatctcggcgggggctgagcacagcagagatgaatgcagta gaggccattcatagagctgtggaattcaatcctcatgtgccaaaatacctactagaaatg aaaagcttaatcctacccccagaacatatcctgaagagaggagacagtgaagcaatagca tatgcattctttcatcttgcacactggaagagagtggaaggggctttgaatcttttgcat tgtacgtgggaaggcacttttcggatgatcccttatcccttggaaaaggggcacctattt tatccttacccaatctgtacagaaacagcagaccgagagctgcttccatctttccatgaa gtctcagtttacccaaagaaggagcttcccttctttattctctttactgctggattatgt tccttcacagccatgctggccctcctgacacatcagttcccggaacttatgggggtcttc gcaaaagctttcctcagcactttgtttgcccccttaaactttgtcatggagaaagtggag agcatcctcccatccagtctgtggcaccagctaacacggatctga |
Protein Sequence |
>7982 : length: 554 MAEAATGFLEQLKSCIVWSWTYLWTVWFFIVLFLVYILRVPLKINDNLSTVSMFLNTLTP KFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNNSSNNSNSSN GDSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDS DHLRPADAIMQKAWRERNPQARISAAHEALEINECATAYILLAEEEATTIAEAEKLFKQA LKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCARRLGRTREAVKMMRDLM KEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSD KFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIA YAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHE VSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAFLSTLFAPLNFVMEKVE SILPSSLWHQLTRI |