|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 8406 |
Name | SRPX |
Synonym | DRS|ETX1|SRPX1;sushi-repeat containing protein, X-linked;SRPX;sushi-repeat containing protein, X-linked |
Definition | sushi repeat-containing protein SRPX|sushi-repeat-containing protein, X chromosome|sushi-repeat-containing protein, X-linked |
Position | Xp21.1 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 5 PubMed records as below. |
|
Evidence Status |
Description |
reviewed | Downregulation of drs tumor suppressor gene in highly malignant human pulmonary neuroendocrine tumors. |
potential | "down-regulation of drs mRNA is closely correlated with carcinomas which arise from adenomatous polyps in the course of the adenoma-carcinoma sequence, but most carcinomas arising de novo are independent of the tumor suppressor function of the drs gene". |
reviewed | Suppression of viral replication by drs tumor suppressor via mTOR dependent pathway. |
reviewed | The drs tumor suppressor is involved in the maturation process of autophagy induced by low serum. |
potential | Isolation of a novel variant of the tumor suppressor gene (mDRS-2). |
| More detail of all 5 literatures about SRPX | |
|
External Links |
|
Links to Entrez Gene | 8406 |
Links to all GeneRIF Items | 8406 |
Links to iHOP | 8406 |
|
Sequence Information |
|
Nucleotide Sequence |
>8406 : length: 1335 atggggagccccgcacatcggcccgcgctgctgctgctgctgccgcctctgctgctgctg ctgctgctgcgcgtcccgcccagccgcagcttcccagataccccgtggtgctcccccatc aaggtgaagtatggggatgtgtactgcagggcccctcaaggaggatactacaaaacagcc ctgggaaccaggtgcgacattcgctgccagaagggctacgagctgcatggctcttcccta ctgatctgccagtcaaacaaacgatggtctgacaaggtcatctgcaaacaaaagcgatgt cctacccttgccatgccagcaaatggagggtttaagtgtgtagatggtgcctactttaac tcccggtgtgagtattattgttcaccaggatacacgttgaaaggggagcggaccgtcaca tgtatggacaacaaggcctggagcggccggccagcctcctgtgtggatatggaacctcct agaatcaagtgcccaagtgtgaaggaacgcattgcagaacccaacaaactgacagtccgg gtgtcctgggagacacccgaaggaagagacacagcagatggaattcttactgatgtcatt ctaaaaggcctccccccaggctccaactttccagaaggagaccacaagatccagtacaca gtctatgacagagctgagaataagggcacttgcaaatttcgagttaaagtaagagtcaaa cgctgtggcaaactcaatgccccagagaatggttacatgaagtgctccagcgacggtgat aattatggagccacctgtgagttctcctgcatcggcggctatgagctccagggtagccct gcccgagtatgtcaatccaacctggcttggtctggcacggagcccacctgtgcagccatg aacgtcaatgtgggtgtcagaacggcagctgcacttctggatcagttttatgagaaaagg agactcctcattgtgtccacacccacagcccgaaacctcctttaccggctccagctagga atgctgcagcaagcacagtgtggccttgatcttcgacacatcaccgtggtggagctggtg ggtgtgttcccgactctcattggcaggataggagcaaagattatgcctccagccctagcg ctgcagctcaggctgttgctgcgaatcccactctactccttcagtatggtgctagtggat aagcatggcatggacaaagagcgctatgtctccctggtgatgcctgtggccctgttcaac ctgattgacacttttcccttgagaaaagaagagatggtcctacaagccgaaatgagccag acctgtaacacctga |
Protein Sequence |
>8406 : length: 444 MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPDTPWCSPIKVKYGDVYCRAPQGGYYKTA LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRCPTLAMPANGGFKCVDGAYFN SRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKERIAEPNKLTVR VSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVRVK RCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAM NVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELV GVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVDKHGMDKERYVSLVMPVALFN LIDTFPLRKEEMVLQAEMSQTCNT |