Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

8406

Name

SRPX

Synonym

DRS|ETX1|SRPX1;sushi-repeat containing protein, X-linked;SRPX;sushi-repeat containing protein, X-linked

Definition

sushi repeat-containing protein SRPX|sushi-repeat-containing protein, X chromosome|sushi-repeat-containing protein, X-linked

Position

Xp21.1

Gene Type

protein-coding

Source

Count: 2; Pubmed_search,Generif

Literature support

Count: 5 PubMed records as below.

Evidence Status

Description

reviewed

Downregulation of drs tumor suppressor gene in highly malignant human pulmonary neuroendocrine tumors.

potential

"down-regulation of drs mRNA is closely correlated with carcinomas which arise from adenomatous polyps in the course of the adenoma-carcinoma sequence, but most carcinomas arising de novo are independent of the tumor suppressor function of the drs gene".

reviewed

Suppression of viral replication by drs tumor suppressor via mTOR dependent pathway.

reviewed

The drs tumor suppressor is involved in the maturation process of autophagy induced by low serum.

potential

Isolation of a novel variant of the tumor suppressor gene (mDRS-2).
More detail of all 5 literatures about SRPX

External Links

Links to Entrez Gene

8406

Links to all GeneRIF Items

8406

Links to iHOP

8406

Sequence Information

Nucleotide Sequence

>8406 : length: 1335
atggggagccccgcacatcggcccgcgctgctgctgctgctgccgcctctgctgctgctg
ctgctgctgcgcgtcccgcccagccgcagcttcccagataccccgtggtgctcccccatc
aaggtgaagtatggggatgtgtactgcagggcccctcaaggaggatactacaaaacagcc
ctgggaaccaggtgcgacattcgctgccagaagggctacgagctgcatggctcttcccta
ctgatctgccagtcaaacaaacgatggtctgacaaggtcatctgcaaacaaaagcgatgt
cctacccttgccatgccagcaaatggagggtttaagtgtgtagatggtgcctactttaac
tcccggtgtgagtattattgttcaccaggatacacgttgaaaggggagcggaccgtcaca
tgtatggacaacaaggcctggagcggccggccagcctcctgtgtggatatggaacctcct
agaatcaagtgcccaagtgtgaaggaacgcattgcagaacccaacaaactgacagtccgg
gtgtcctgggagacacccgaaggaagagacacagcagatggaattcttactgatgtcatt
ctaaaaggcctccccccaggctccaactttccagaaggagaccacaagatccagtacaca
gtctatgacagagctgagaataagggcacttgcaaatttcgagttaaagtaagagtcaaa
cgctgtggcaaactcaatgccccagagaatggttacatgaagtgctccagcgacggtgat
aattatggagccacctgtgagttctcctgcatcggcggctatgagctccagggtagccct
gcccgagtatgtcaatccaacctggcttggtctggcacggagcccacctgtgcagccatg
aacgtcaatgtgggtgtcagaacggcagctgcacttctggatcagttttatgagaaaagg
agactcctcattgtgtccacacccacagcccgaaacctcctttaccggctccagctagga
atgctgcagcaagcacagtgtggccttgatcttcgacacatcaccgtggtggagctggtg
ggtgtgttcccgactctcattggcaggataggagcaaagattatgcctccagccctagcg
ctgcagctcaggctgttgctgcgaatcccactctactccttcagtatggtgctagtggat
aagcatggcatggacaaagagcgctatgtctccctggtgatgcctgtggccctgttcaac
ctgattgacacttttcccttgagaaaagaagagatggtcctacaagccgaaatgagccag
acctgtaacacctga

Protein Sequence

>8406 : length: 444
MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPDTPWCSPIKVKYGDVYCRAPQGGYYKTA
LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRCPTLAMPANGGFKCVDGAYFN
SRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKERIAEPNKLTVR
VSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVRVK
RCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAM
NVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELV
GVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVDKHGMDKERYVSLVMPVALFN
LIDTFPLRKEEMVLQAEMSQTCNT



Copyright © 2016-Present - The Univsersity of Texas Health Science Center at Houston Rights Reserved
Site Policies | State of Texas