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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 84260 |
Name | TCHP |
Synonym | TpMs;trichoplein, keratin filament binding;TCHP;trichoplein, keratin filament binding |
Definition | mitochondrial protein with oncostatic activity|mitostatin|trichoplein keratin filament-binding protein|tumor suppressor protein |
Position | 12q24.11 |
Gene Type | protein-coding |
Source | Count: 2; Generif,UniProt |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
reviewed | "MITOSTATIN was found within a 3.2-kb transcript for an approximately 62 kDa mitochondrial protein with tumor suppressor activity. It inhibits cell growth, is proapoptotic and downregulates Hsp27." |
reviewed | MITOSTATIN may acts as a tumor suppressor gene in prostate cancer. |
| More detail of all 2 literatures about TCHP | |
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External Links |
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Links to Entrez Gene | 84260 |
Links to all GeneRIF Items | 84260 |
Links to iHOP | 84260 |
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Sequence Information |
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Nucleotide Sequence |
>84260 : length: 1497 atggcgctcccgacgctgccgtcctactggtgcagccagcagcgcctgaatcagcagcta gcacgacagcgagagcaggaggcccggcttcggcagcagtgggagcagaacagccgttac ttcaggatgtctgacatctgcagctccaaacaggcagaatggagctctaaaacctcctac cagcggagcatgcatgcctatcagcgggagaagatgaaggaggagaagaggaggagtctg gaggcccgacgggaaaagctcaggcagctcatgcaggaggagcaggacctgctggccaga gaactggaggagctgaggctgagcatgaacttgcaggaaagaagaatccgggagcagcac gggaagctgaaatcagccaaagaagagcagaggaaactgattgctgaacaacttttgtac gaacactggaaaaagaacaacccgaaacttcgagagatggagctggaccttcaccagaag catgtcgtaaactcttgggaaatgcagaaagaagaaaaaaaacagcaagaagccaccgca gagcaagagaacaaacggtatgaaaatgaatatgaaagggcccgaagggaggcgctagaa aggatgaaagctgaagaggagaggaggcagctggaggacaagctccaggccgaggcactg ctgcaacagatggaggagctgaagctgaaggaggtggaggcgaccaaactaaagaaggag caggagaatctgttgaagcagcggtgggagctagagaggctggaggaagagcgaaagcag atggaagccttccggcagaaggcagagctggggcgtttcttgagacatcagtataacgct caactcagcagacgcacacagcagatccaagaggagctggaggcagacaggcggatcctg caggccctcctcgagaaggaggacgagagccagcgcctccacctggccaggcgggagcag gtcatggccgatgtggcctggatgaagcaggccattgaggagcagctgcagctggagcgg gcgcgggaggcagagctgcagatgctgctgagggaggaggccaaggagatgtgggaaaag agagaggcagagtgggcccgagagcgcagcgcacgggacagactgatgagcgaggttctg acagggagacaacagcaaatacaagagaagattgagcagaaccgacgggcacaagaggaa tccctgaaacacagggagcaacttattcgaaatcttgaggaggtgagagagttggctcgt cgcgagaaagaggagagtgaaaagctgaaatcggccaggaagcaggagctggaagcccag gttgcagagcgccggctgcaggcatgggaagcagaccagcaggaggaggaggaagaggag gaggcccggcgggtcgagcagctctcagatgccctgctgcagcaggaggcggagactatg gctgagcagggctaccggcctaagccttacggacatccaaaaattgcttggaactga |
Protein Sequence |
>84260 : length: 498 MALPTLPSYWCSQQRLNQQLARQREQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSY QRSMHAYQREKMKEEKRRSLEARREKLRQLMQEEQDLLARELEELRLSMNLQERRIREQH GKLKSAKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATA EQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKE QENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRIL QALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEMWEK REAEWARERSARDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELAR REKEESEKLKSARKQELEAQVAERRLQAWEADQQEEEEEEEARRVEQLSDALLQQEAETM AEQGYRPKPYGHPKIAWN |